Classification of submucosal tumors in the gastrointestinal tract

Figure 1 Exophytic leiomyosarcoma of the ileum, measuring 6 cm x 5 cm x 3 cm. A fibrin coated mucosa with stigmata of hemorrhage and discolorations of the adjacent mucosa can be seen (Courtesy by S Duun).

Figure 2 Cut surface of the leiomyosarcoma presented in Figure 1, showing a possible necrosis and a white, fish-flesh-like color, as typical for sarcomas. The surface did not bulge on incision (Courtesy by S Duun).

Figure 3 The leiomyosarcoma presented in Figures 1 and 2. It is of low malignancy, but shows nuclear atypia, pleomorphism and mitoses. (HE, x 100) (Courtesy by S Duun).

Figure 4 Histological findings of a GIST showing a positive CD117 immunohisto-chemical reaction. (× 200) (Courtesy by B Vainer).