Effect of hydroxyapatite nanoparticles on the growth and p53/c-Myc protein expression of implanted hepatic VX2 tumor in rabbits by intravenous injection

Figure 1 A: The mutated p53 positive expression in tumor tissue (× 200); B: c-myc positive expression in tumor tissue (× 200).

Figure 2 A: The outward appearance of VX₂ liver tumor the metastatic carcinoma on lung in control group; B: The metastatic carcinoma on lung in control group.

Figure 3 A: There are apparent morphological differences between VX₂ liver tumor tissue and the normal liver tissue (× 200); B: There are lots of calcified points in tumor tissue in group treated by nano-HAP (× 100).