A case of interstitial pneumonitis in a patient with ulcerative colitis treated with azathioprine

Figure 1 Chest X-ray (2003-09-09) showing moderate reticular enhancement with ring-like consolidation in both lungs (but predominantly the right), without cardiac or aortic abnormalities.

Figure 2 Chest X-ray (2003-09-14) showing significant progression and volume loss in both lungs. A palm-sized homogeneous consolidation developed in the central part of the lung, a marked interstitial enhancement was seen in other parts of the lung. The radiological image suggested ARDS. The heart was enlarged.

Figure 3 Histology of lung needle biopsy (HE, 112 ×).

Figure 4 Histology showing the pathognomic Masson bodies for BOOP and polypous proliferation of new connective tissue in the alveolus (trichrome, 224 ×).

Figure 5 Immunohistochemistry for the expression of CK 7. Interstitial fibrosis and proliferation of type II pneumocytes are apparent (224 ×).

Figure 6 Chest X-ray (2003-10-15) showing improvement of lung volumes. Reticular enhancement of the middle part of the lungs is still present.