Twenty-four hour intra-arterial infusion of 5-fluorouracil, cisplatin, and leucovorin is more effective than 6-hour infusion for advanced hepatocellular carcinoma

Figure 1 Survival curves plotted by the Kaplan-Meier method. The survival of group L was significantly better than that of group S. The median survival time was 496 d in group L versus 226 d in group S (^aP < 0.05, Kaplan-Meier method and log-rank test).

Figure 2 Changes of serum AFP following treatment in the both groups. In group L, the serum AFP level decreased significantly after treatment compared with before treatment (^aP < 0.05, Mann-Whitney test).

Figure 3 Changes of the white blood cell count following treatment in the both groups. There were no significant differences in either group.

Figure 4 Changes of neutrophil and monocyte counts following treatment in the both groups. In group L, the neutrophil and monocyte counts were significantly decreased after treatment as compared with before treatment (^aP < 0.05, Mann-Whitney test).