Effects of intra-gastric beta-casomorphin-7 on somatostatin and gastrin gene expression in rat gastric mucosa

Figure 1 Effect of beta-casomorphin-7 on gastrin and somatostatin mRNA expression by RT-PCR. (A) and (B): graphs of RT-PCR analysis. (C) and (D): densitometric analysis of somatostatin and gastrin signals over beta-actin signals. The vertical lines indicate the mean ± SE of three different experiments. ^aP < 0.05 vs control group, ^bP < 0.01 vs control group.

Figure 2 In situ hybridization for gastrin and somatostatin mRNA in rat gastric mu-cosa. The oligonucleotide probes were labeled with digoxigenin. A: gastrin, corpus; B: gastrin, antrum; C: somatostatin, corpus; D: somatostatin, antrum. All of the sections magnify at 100 (10 × 10) and stained with DAB. The positive cells show brown precipitate at the site of digoxigenin-probe hybridization (black arrows).