Role of cyclooxygenase-2 in the carcinogenesis of gastrointestinal tract cancers: A review and report of personal experience

Figure 1 COX-2 mRNA expression and PGE2 production of esophageal mucosa. ^aP < 0.005 vs sham; ^bP < 0.01 between the two groups , Mann-Whitney U test

Figure 2 Cell kinetics of esophageal mucosa in a duodenoesophageal reflux model. ^aP < 0.05 vs sham; ^cP < 0.05 between the two groups , Mann-Whitney U test

Figure 3 Percentage change from the baseline in the number of colorectal polyps in FAP patients

Figure 4 Percentage of responders who showed a 25% or more decrease in the mean number of colorectal polyps