Isolated splenic vein thrombosis secondary to splenic metastasis: A case report

Figure 1 Contrast-enhanced computed tomography of the abdomen. A: Enlarged spleen with hypodense lesion in the superior spleen which was considered to be splenic metastasis; B: Hypoattenuating thrombus in the splenic vein and the portal vein.

Figure 2 Digital substraction angiography. A: The venous phase of the celiac artery angiogram reveals occlusion of the splenic vein and development of collaterals; B: The venous phase of the superior mesenteric artery angiogram reveals a defect shadow in the portal vein at its junction with the splenic vein.

Figure 3 Histological findings of the tumor of the ascending colon. A: Moderately differentiated adenocarcinoma (HE, x 20); B: Immunostaining for cytokeratin 7 showing a negative reaction (x 20); C: Immunostaining for cytokeratin 20 showing a positive reaction (x 20).

Figure 4 Histological findings of the tumor of the spleen. A: Moderately differentiated adenocarcinoma (HE x 20); B: Immunostaining for cytokeratin 7 showing a negative reaction (x 20); C: Immunostaining for cytokeratin 20 showing a positive reaction (x 20).

Figure 5 Histological findings of the splenic vein filled with not tumor thrombus, but organizing thrombus. The elastic tissue ring is intact (HE, x 4).