Pancreatic cancer with a high serum IgG4 concentration

Figure 1 Immunostaining of IgG4 in the resected specimens. Abundant IgG4-positive plasma cells were detected in the cancerous lesion of the pancreas (A) but only a few IgG4-positive plasma cells were seen in the noncancerous areas of the pancreas (B). Infiltration of abundant IgG4-positive plasma cells was detected in regional lymph node (C) and the duodenal mucosa (D).

Figure 2 Course of serum IgG4 levels in this patient. Elevated serum IgG4 levels continued after operation.