Development of ulcerative colitis during the course of rheumatoid arthritis: Association with selective IgA deficiency

Figure 1 Barium enema shows loss of mucosal pattern with speculation, absent haustration, narrowing and shortening of the bowel, extending from the rectum to the distal transverse colon.

Figure 2 (A) Sigmoidoscopy revealed friable, edematous mucosa with granularity, mucous exudates and bleeding throughout the rectum and sigmoid colon. Multiple erosions and punctate ulcers were observed without normal-appearing intervening mucosa. (B) Repeated colonoscopy before discharge revealed almost normal mucosa from the distal transverse colon to the rectum.

Figure 3 Histopathological examination of biopsied rectal mucosa showed severe neutrophil infiltration, goblet cell depletion and mild crypt abscess (hematoxylin and eosin staining).