Rabeprazole test for the diagnosis of gastro-oesophageal reflux disease: Results of a study in a primary care setting

Figure 1 Diagrammatic illustration of the different phases of the study. Two visits were carried out by the investigator physician (V1: inclusion; and V3: final assessment). The second visit (V2) was carried out by the referent physician to check the inclusion criteria, to perform endoscopy (unless the patients had already undergone one endoscopy during the previous 6 months) and 24-h esophageal pH monitoring.

Figure 2 Receiver operating characteristics (ROC) curve. This was determined according to various satisfaction criteria (from “very slight improvement” to “resolution” of the symptoms) for patients with symptoms compatible with gastro-esophageal reflux. The symptoms were assessed after one week of treatment with a double dose of rabeprazole (20 mg bid) or a placebo.