Inhibition of p38 mitogen-activated protein kinase may decrease intestinal epithelial cell apoptosis and improve intestinal epithelial barrier function after ischemia- reperfusion injury

Figure 1 Changes of p38 mitogen-activated protein kinase activities in intestinal tissue after I/R (A) and of different groups after I/R (B). ^aP<0.05 vs I/R vehicle group.

Figure 2 Apoptotic cell rate in intestinal tissue after I/R in I/R vehicle group (A) and apoptotic cells rate in intestinal tissue after I/R in I/R vehicle and SB 203580 treated groups (B). ^aP<0.05 vs I/R vehicle group.

Figure 3 Plasma D-lactate level in intestinal tissue after I/R in I/R vehicle group (A) and plasma D-lactate level in intestinal tissue after I/R in I/R vehicle and SB 203580 treated groups (B). ^aP<0.05 vs I/R vehicle group.

Figure 4 Villus structure. A: Before I/R in sham-operation group; B: Structural changes of the villus after I/R in I/R vehicle group; C: Structural changes of the villus after I/R in SB 203580 treated group.