Induction of hepatitis C virus-specific cytotoxic T and B cell responses by dendritic cells expressing a modified antigen targeting receptor

Figure 1 pcDNA 3HCV-Fc vectors identified by restriction enzyme analysis. Lane 1: Marker (Ecoli); lane 2: pcDNA3; lane 3: pcDNA 3HCV-Fc was cut by restriction enzyme Xho I/Xba I; lane 4: Fc cDNA fragment was cloned into the vector; lane 5: Marker (DL-2000).

Figure 2 Expression of HCV C-Fc fusion proteins.

Figure 3 BM-derived DCs. A: BM-derived DC (SEM×500); B: BM-derived DC (SEM×700).

Figure 4 Serum anti-HCV C level in Balb/c mice. ^bP<0.01 vs pcDNA3