Effect of Astragalus complanatus flavonoid on anti-liver fibrosis in rats

Figure 1 Effects of ACF on SOD activity and MDA content in rat liver tissue (A) and on PINP and PIIINP contents in rats serum (B). ^aP < 0.05, ^bP < 0.01 vs model group.

Figure 2 Analysis of MMP-1 mRNA expression in rat hepatic tissue. M: molecular weight markers (bp); lane 1: normal group; lane 2: model group; lane 3: colchicine group; lane 4: ACF-1 group; lane 5: ACF-2 group; lane 6: ACF-3 group; n = 4.^aP < 0.05, ^bP < 0.01 vs model group.

Figure 3 Immunohistochemical expression of TIMP-1 protein in rat hepatic tissue. (1) The positive ratio detected by Jieda 501 image-analysis system was used as the total protein expression. (2) TIMP-1 is shown as yellow grains in hepatic tissue (immunohistochemistry, ×200). A: normal group; B: model group; C: colchicine group; D: ACF-1 group; E: ACF-2 group; F: ACF-1 group; n = 5. ^aP < 0.05, ^bP < 0.01 vs model group.