Effect of NS-398 on colon cancer cells

Figure 1 Expression of COX-2 detected by flow cytometry in negative control (A) and HT-29 cells (B).

Figure 2 F-actin structure disrupted by NS-398 in colon cancer HT-29 cells. F-actin was mainly distributed around nuclei to take on annular structure (↑) in control cells (A). Annular structure around nuclei was disorganized after treatment with NS-398 at 10 μmol/L (B).

Figure 3 Expression of CD44v6 in negative control (A) and HT-29 cells without treatment as control (B), following 72-h treatment of NS-398 at 0. 1 μmol/L (C), 1.0 μmol/L (D) and 10 μmol/L (E).