Isoflurane preserves energy balance in isolated hepatocytes during in vitro anoxia/reoxygenation

Figure 1 Dependence of ATP, ADP, AMP and total adenine nucleotide and energy charge in isolated hepatocytes on isoflurane during 30 min exposure to anoxia (A), anesthetic and oxygenation status during 30-35 min incubation (B) and during 60-70 min incubation (C). Iso, isoflurane; O₂, oxygenated; N₂, anoxic; ReO₂, reoxygenated after anoxia. Values shown are means for n = 8 experiments. ^aP < 0.05 vs initial values at 0% isoflurane; ^cP < 0.05 vs control groups (isoflurane absent).