Comparison of six human anti-transglutaminase ELISA-tests in the diagnosis of celiac disease in the Saharawi population

Figure 1 IgA anti-tissue transglutaminase (tTG) antibody values with six human tTG based enzyme linked immuno-absorbent assay (ELISA) tests in both anti-endomysium (EmA) positive celiac disease (CD) patients and controls, with corresponding receiver operating characteristic (ROC) curves and area under curve (AUC) estimations. The broken lines represent the limits proposed by the manufacturers, whereas the solid lines show the cut-off values yielding the best combination of sensitivity and specificity, according to ROC curve analysis.