Avidin chase reduces side effects of radioimmunotherapy in nude mice bearing human colon carcinoma

Figure 1 Tissue radioactivity at 28 and 48 h after administration of ¹⁸⁸Re-CEA McAb-Bt in groups without (A) and with Av chase (B).

Figure 2 Tumor-to-non-tumor ratios at 28 and 48 h after administration of ¹⁸⁸Re-CEA McAb-Bt in groups without (A) and with Av chase (B).

Figure 3 Radioimmunoimaging in nude mice bearing human colon carcinoma with (A) and without (B) avidin chase at 28 h after administration of ¹⁸⁸Re-CEA McAb-Bt.

Figure 4 Change of the number of peripheral blood white blood cells after injection of avidin chase.

Figure 5 Variation of tumor growth volume (cm³) in groups before and after therapy.