Expression of cytochrome P4502E1 gene in hepatocellular carcinoma

Figure 1 Differential expression profile of cDNA array hy-bridization result. Part of the membrane is displayed. The clones the arrows point represent CYP2E1. K: HCC tissue, L: adjacent liver tissue.

Figure 2 CYP2E1 expression in normal human organs and HCC tissues detected by Northern blot analysis. 1: heart, 2: brain, 3: muscle, 4: intestine, 5: stomach, 6: lung, 7: liver tissues adjacent to HCC, 8: HCC, 9: liver tissues adjacent to HCC, 10: HCC, 11: renal tissues adjacent to carcinoma, 12: renal carcinoma.

Figure 3 CYP2E1 expression in normal organs of rat detected by RT-PCR analysis.

Figure 4 CYP2E1 expression in human HCC tissues detected by Northern blot analysis. N: normal liver, K: HCC, L: liver tissue adjacent to HCC.

Figure 5 CYP2E1 expression in occurrence and development of rat HCC detected by Northern blot analysis. There were 12 lanes in one membrane including specimen of 3 wk. Riboso-mal RNA of 28 s and 18 s as control was in the bottom. N: nor-mal control group, D: DENA-induced group.