Original Article
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World J Gastroenterol. May 28, 2013; 19(20): 3007-3017
Published online May 28, 2013. doi: 10.3748/wjg.v19.i20.3007
A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes
Ignazio Grattagliano, Catia V Diogo, Maria Mastrodonato, Ornella de Bari, Michele Persichella, David QH Wang, Adriana Liquori, Domenico Ferri, Maria Rosaria Carratù, Paulo J Oliveira, Piero Portincasa
Ignazio Grattagliano, Piero Portincasa, Section of Internal Medicine, Department of Interdisciplinary Medicine, University of Bari, 70124 Bari, Italy
Catia V Diogo, Paulo J Oliveira, Center for Neuroscience and Cell Biology, Largo Marques de Pombal, University of Coimbra, P-3004-517 Coimbra, Portugal
Maria Mastrodonato, Adriana Liquori, Domenico Ferri, Laboratory of Histology and Comparative Anatomy, Department of Animal and Environmental Biology, University of Bari, 70125 Bari, Italy
Ornella de Bari, David QH Wang, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Edward Doisy Research Center, Saint Louis University School of Medicine, Saint Louis, MO 63104, United States
Michele Persichella, Maria Rosaria Carratù, Department of Pharmacology and Human Physiology, University of Bari, 70124 Bari, Italy
Author contributions: Grattagliano I and Portincasa P designed the study and wrote the article; Diogo CV, de Bari O, Persichella M, Carratù MR; and Oliveira PJ performed experiments and measurements; Mastrodonato M, Liquori A; and Ferri D performed histology; Wang DQH did statistics.
Supported by Grants from MIUR (Ministero Università e Ricerca Scientifica COFIN2006) and “Fondi Ateneo Ricerca Scientifica 2005/2006” from the University of Bari, Italy
Correspondence to: Piero Portincasa, MD, PhD, Section of Internal Medicine, Department of Interdisciplinary Medicine, University of Bari, Piazza G. Cesare, 11, 70124 Bari, Italy. p.portincasa@semeiotica.uniba.it
Telephone: +39-80-5478227 Fax: +39-80-5478232
Received: September 14, 2012
Revised: November 6, 2012
Accepted: November 11, 2012
Published online: May 28, 2013
Processing time: 255 Days and 22.4 Hours
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