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World J Gastroenterol. Nov 21, 2012; 18(43): 6226-6234
Published online Nov 21, 2012. doi: 10.3748/wjg.v18.i43.6226
Published online Nov 21, 2012. doi: 10.3748/wjg.v18.i43.6226
Insights into erlotinib action in pancreatic cancer cells using a combined experimental and mathematical approach
Falko Lange, Katja Rateitschak, Christina Kossow, Olaf Wolkenhauer, Department of Systems Biology and Bioinformatics, University of Rostock, 18057 Rostock, Germany
Falko Lange, Robert Jaster, Department of Medicine II, Division of Gastroenterology, University Medicine Rostock, 18057 Rostock, Germany
Olaf Wolkenhauer, Stellenbosch Institute for Advanced Study, Wallenberg Research Centre at Stellenbosch University, Stellenbosch 7600, South Africa
Author contributions: Lange F and Rateitschak K contributed equally to this work; Wolkenhauer O, Lange F, Rateitschak K and Jaster R designed the study; Lange F performed the experiments; Rateitschak K and Lange F designed the mathematical model; Lange F, Rateitschak K, Kossow C, Wolkenhauer O, Jaster R analyzed the data; Jaster R and Lange F wrote the manuscript.
Supported by A grant of the Bundesministerium für Bildung und Forschung through the FORSYS partner program, No. 0315255; and the Helmholtz Society as part of the Systems Biology Network
Correspondence to: Robert Jaster, MD, Department of Medicine II, Division of Gastroenterology, University Medicine Rostock, E-Heydemann-Str 6, 18057 Rostock, Germany. jaster@med.uni-rostock.de
Telephone: +49-381-4947349 Fax: +49-381-4947482
Received: May 9, 2012
Revised: August 27, 2012
Accepted: September 12, 2012
Published online: November 21, 2012
Revised: August 27, 2012
Accepted: September 12, 2012
Published online: November 21, 2012
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