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World J Gastroenterol. Feb 28, 2011; 17(8): 976-986
Published online Feb 28, 2011. doi: 10.3748/wjg.v17.i8.976
Published online Feb 28, 2011. doi: 10.3748/wjg.v17.i8.976
Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells
Ho-Keun Kwon, Ji-Sun Hwang, Choong-Gu Lee, Jae-Seon So, Anupama Sahoo, Zee Yong Park, Sin-Hyeog Im, School of Life Sciences and Immune Synapse Research Center, Gwangju Institute of Science and Technology, Gwangju 500-712, South Korea
Chang-Rok Im, Global leader program, Bugil Academy, Cheonan, Gyeonggido 330-941, South Korea
Won Kyung Jeon, Byoung Seob Ko, Korea Institute of Oriental Medicine, Daejeon 305-811, South Korea
Sung Haeng Lee, Chosun University School of Medicine, Gwangju 501-759, South Korea
Author contributions: Kwon HK performed the majority of experiments; Hwang JS, Lee CG and So JS performed TNBS-induced colitis and data analysis; Sahoo A and Im CR gave help with manuscript correction; Jeon WK, Ko BS and Lee SH prepared water soluble fractions of cinnamon extract and performed HPLC and MALDI analysis for quality control; Park ZY and Im SH designed and financed this study.
Supported by Grants from the BioGreen 21 Program, Rural Development Administration (PJ007054), Regional Technology Innovation Program of the MOCIE (RTI05-01-01) and by Korea Healthcare Technology R&D Project, Ministry of Health and Welfare (A080588-20)
Correspondence to: Dr. Sin-Hyeog Im, School of Life Sciences and Immune Synapse Research Center, Gwangju Institute of Science and Technology, Gwangju 500-712, South Korea. imsh@gist.ac.kr
Telephone: +82-62-7152503 Fax: +82-62-7152484
Received: September 20, 2010
Revised: November 25, 2010
Accepted: December 2, 2010
Published online: February 28, 2011
Revised: November 25, 2010
Accepted: December 2, 2010
Published online: February 28, 2011
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