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World J Gastroenterol. Sep 7, 2011; 17(33): 3802-3809
Published online Sep 7, 2011. doi: 10.3748/wjg.v17.i33.3802
Published online Sep 7, 2011. doi: 10.3748/wjg.v17.i33.3802
Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution
Tomohisa Takagi, Yuji Naito, Kazuhiko Uchiyama, Toshimitsu Okuda, Katsura Mizushima, Takahiro Suzuki, Osamu Handa, Takeshi Ishikawa, Nobuaki Yagi, Satoshi Kokura, Hiroshi Ichikawa, Toshikazu Yoshikawa, Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 602-8566 Kyoto, Japan
Author contributions: Takagi T and Naito Y conceived the experiments; Okuda T, Suzuki T and Ishikawa T performed the majority of in vivo experiments; Uchiyama K and Hand O performed the majority of in vitro experiments; Mizushima K, Yagi N and Kokura S performed molecular biological analysis; Takagi T, Ichikawa H and Yoshikawa T analyzed the data and were also involved in editing the manuscript. All authors discussed the results and commented on the manuscript.
Supported by A Grant-in-Aid for Scientific Research (B) to Toshikazu Yoshikawa (Grant No. 21390184) and Challenging Exploratory Research to Yuji Naito (No. 08101559) from the Japan Society for the Promotion of Science; A City Area Program to Toshikazu Yoshikawa and Yuji Naito from Ministry of Education, Culture, Sports, Science and Technology, Japan; An Adaptable and Seamless Technology Transfer Program through target-driven R&D to Yuji Naito from Japan Science and Technology Agency
Correspondence to: Yuji Naito, MD, PhD, Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, 602-8566 Kyoto, Japan. ynaito@koto.kpu-m.ac.jp
Telephone: +81-75-2515508 Fax: +81-75-2510710
Received: December 2, 2010
Revised: January 18, 2011
Accepted: January 25, 2011
Published online: September 7, 2011
Revised: January 18, 2011
Accepted: January 25, 2011
Published online: September 7, 2011
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