Soluble ST2: A new and promising activity marker in ulcerative colitis

doi:10.3748/wjg.v17.i17.2181

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2011; 17(17): 2181-2190
Published online May 7, 2011. doi: 10.3748/wjg.v17.i17.2181

Soluble ST2: A new and promising activity marker in ulcerative colitis

David Díaz-Jiménez, Lucía E Núñez, Caroll J Beltrán, Enzo Candia, Cristóbal Suazo, Manuel Álvarez-Lobos, María-Julieta González, Marcela A Hermoso, Rodrigo Quera

David Díaz-Jiménez, Lucía E Núñez, Caroll J Beltrán, Enzo Candia, Marcela A Hermoso, Disciplinary Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, CL 8380453, Chile

Caroll J Beltrán, Department of Clinical Investigation, Hospital Clínico de la Universidad de Chile, Santiago, CL 8380456, Chile

Cristóbal Suazo, Laboratory of Oncology and Molecular Genetics, Colorectal Surgery Unit, Clínica Las Condes, Lo Fontecilla 441, Santiago, CL 7591046, Chile

Manuel Álvarez-Lobos, Department of Gastroenterology, Pontificia Universidad Católica de Chile, Santiago, CL 8380074, Chile

María-Julieta González, Cell and Molecular Biology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago, CL 8380453, Chile

Rodrigo Quera, Gastroenterology Unit, Department of Internal Medicine, Hospital Clínico de la Universidad de Chile, Santiago, CL 8380456, Chile

Rodrigo Quera, Gastroenterology Unit, Clínica Las Condes, Lo Fontecilla 441, Santiago, CL 7591046, Chile

Author contributions: Díaz-Jiménez D and Núñez LE performed the majority of experiments; Beltrán CJ and Candia E were also involved in performing some experiments and collected patient information; Hermoso MA and González MJ provided vital reagents and analytical tools and edited the manuscript; Quera R co-ordinated and provided the collection of all the human material in addition to providing financial support for this work; Suazo C and Álvarez-Lobos M also provided human samples; Hermoso MA designed the study; Hermoso MA and Díaz-Jiménez D wrote the manuscript; Hermoso MA and Quera R share senior authorship.

Supported by FONDECYT grant 1070954 and DA-CLC 2803

Correspondence to: Rodrigo Quera, MD, Gastroenterology Unit, Clínica Las Condes, Lo Fontecilla 441, Santiago, CL 7591046, Chile. rquera@clinicalascondes.cl

Telephone: +56-2-6108755 Fax: +56-2-6108719

Received: July 22, 2010
Revised: October 15, 2010
Accepted: October 22, 2010
Published online: May 7, 2011

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