Alanine aminotransferase is an inadequate surrogate marker for detecting lamivudine resistance

doi:10.3748/wjg.v16.i37.4691

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Oct 7, 2010 (publication date) through Apr 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2010; 16(37): 4691-4696
Published online Oct 7, 2010. doi: 10.3748/wjg.v16.i37.4691

Alanine aminotransferase is an inadequate surrogate marker for detecting lamivudine resistance

Lee Guan Lim, Myat Oo Aung, Bee Leng Seet, Cindy Tan, Yock Young Dan, Yin Mei Lee, Dede Selamat Sutedja, Mark Fernandes, Guan Huei Lee, Evelyn Koay, Seng Gee Lim

Lee Guan Lim, Myat Oo Aung, Yock Young Dan, Yin Mei Lee, Dede Selamat Sutedja, Mark Fernandes, Guan Huei Lee, Seng Gee Lim, Department of Gastroenterology and Hepatology, National University Health System, Yong Yoo Lin School of Medicine, National University of Singapore, Singapore 128791, Singapore

Bee Leng Seet, Cindy Tan, Yock Young Dan, Seng Gee Lim, Department of Medicine, National University Health System, Yong Yoo Lin School of Medicine, National University of Singapore, Singapore 128791, Singapore

Evelyn Koay, Molecular Diagnostic Centre, National University Health System, Yong Yoo Lin School of Medicine, National University of Singapore, Singapore 128791, Singapore

Seng Gee Lim, Investigative Medicine Unit, National University Health System, Yong Yoo Lin School of Medicine, National University of Singapore, Singapore 128791, Singapore

Author contributions: Lim LG and Lim SG conceived and designed the study, evaluated the patients, collected, analyzed and interpreted the data; Lim LG wrote and drafted the article; Lim LG and Lim SG revised the paper critically for important intellectual content; Aung MO performed the statistical analysis of the data; Seet BL, Tan C, Dan YY, Lee YM, Sutedja DS, Fernandes M and Lee GH evaluated the patients and collected the data; Koay E also collected the data.

Supported by (in part) Grant 02/N01 from the Health Services Development Program, Ministry of Health, Singapore

Correspondence to: Seng Gee Lim, Professor, Chief, Department of Gastroenterology and Hepatology, National University Health System, Yong Yoo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Rd, Singapore 128791, Singapore. mdclimsg@nus.edu.sg

Telephone: +65-67724369 Fax: +65-67751518

Received: March 13, 2010
Revised: April 24, 2010
Accepted: May 1, 2010
Published online: October 7, 2010

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