Therapy with bone marrow cells reduces liver alterations in mice chronically infected by Schistosoma mansoni

doi:10.3748/wjg.14.5842

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Oct 14, 2008 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2008; 14(38): 5842-5850
Published online Oct 14, 2008. doi: 10.3748/wjg.14.5842

Therapy with bone marrow cells reduces liver alterations in mice chronically infected by Schistosoma mansoni

Sheilla Andrade Oliveira, Bruno Solano Freitas Souza, Carla Adriana Guimarães-Ferreira, Elton Sá Barreto, Siane Campos Souza, Luiz Antonio Rodrigues Freitas, Ricardo Ribeiro-dos-Santos, Milena Botelho Pereira Soares

Sheilla Andrade Oliveira, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, 40295-001 Salvador, BA, Brazil and Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Recife, Av Moraes Rego s/n, Cidade Universitária, Recife 50670-420, PE, Brazil

Bruno Solano Freitas Souza, Carla Adriana Guimarães-Ferreira, Elton Sá Barreto, Siane Campos Souza, Luiz Antonio Rodrigues Freitas, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, Salvador 40295-001, BA, Brazil

Ricardo Ribeiro-dos-Santos, Milena Botelho Pereira Soares, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, 40295-001 Salvador, BA, Brazil and Hospital São Rafael, Av São Rafael, 2152, São Marcos, Salvador 41256-900, BA, Brazil

Author contributions: Oliveira SA designed, conducted the study and analyzed the data; Souza BSF and Barreto ES conducted the morphometric and immunofluorescence studies; Guimarães-Ferreira CA and Souza SC performed FISH and PCR analyses; Freitas LAR performed the histopathological analyses; Ribeiro-dos-Santos R and Soares MBP were involved in designing the study, reviewing and interpreting the results. All authors were involved in drafting the manuscript.

Supported by Instituto do Milênio de Bioengenharia Tecidual (IMBT, CNPq/MCT), Rede Nordeste de Biotecnologia (RENORBIO, FINEP/MCT), Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB) and Fundação Oswaldo Cruz (FIOCRUZ)

Correspondence to: Milena Botelho Pereira Soares, PhD, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, Salvador 40295-001, BA, Brazil. milena@bahia.fiocruz.br

Telephone: +55-71-31762260 Fax: +55-71-31762292

Received: July 8, 2008
Revised: August 21, 2008
Accepted: August 28, 2008
Published online: October 14, 2008

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