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©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jul 14, 2008; 14(26): 4209-4215
Published online Jul 14, 2008. doi: 10.3748/wjg.14.4209
Published online Jul 14, 2008. doi: 10.3748/wjg.14.4209
Gene therapy for type 1 diabetes mellitus in rats by gastrointestinal administration of chitosan nanoparticles containing human insulin gene
Li Niu, Yan-Cheng Xu, Zhe Dai, Hui-Qin Tang, Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China
Author contributions: Niu L and Xu YC contributed equally to this work; Niu L and Xu YC designed the research; Niu L performed the research; Dai Z and Tang HQ contributed to new reagents/analytic tools; Niu L, Xu YC, Dai Z and Tang HQ analyzed the data; Niu L and Xu YC wrote the paper.
Correspondence to: Yan-Cheng Xu, Professor, Department of Endocrinology, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan 430071, Hubei Province, China. endocrine@mail.whu.edu.cn
Telephone: +86-27-62605165
Fax: +86-27-67812892
Received: May 1, 2008
Revised: June 2, 2008
Accepted: June 9, 2008
Published online: July 14, 2008
Revised: June 2, 2008
Accepted: June 9, 2008
Published online: July 14, 2008
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