Basic Research
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. May 7, 2008; 14(17): 2731-2739
Published online May 7, 2008. doi: 10.3748/wjg.14.2731
Mitochondrial protection by low doses of insulin-like growth factor-Iin experimental cirrhosis
Raquel Pérez, María García-Fernández, Matías Díaz-Sánchez, Juan E Puche, Gloria Delgado, Marian Conchillo, Jordi Muntané, Inma Castilla-Cortázar
Raquel Pérez, Matías Díaz-Sánchez, Marian Conchillo, Departments of Human Physiology and Internal Medicine, University of Navarra, Pamplona 31080, Spain
María García-Fernández, Juan E Puche, Gloria Delgado, Inma Castilla-Cortázar, Department of Medical Physiology, School of Medicine, University of Málaga, Málaga 29080, Spain
Juan E Puche, Inma Castilla-Cortázar, Department of Medical Physiology, School of Medicine, University USP-CEU, Madrid 28668, Spain
Jordi Muntané, Department of Internal Medicine, Liver Unit, University of Córdoba, Córdoba 14004, Spain
Author contributions: Pérez R worked on mitochodrial function tests, in vivo treatments; Díaz-Sánchez M worked on TUNEL assay; García-Fernández M contributed to analitical and mitochondrial function tests; Puche JE worked on experimental design and Western blot; Muntané J contributed to Western blot for caspase; Delgado G analyse the data; Conchillo M designed the study; Castilla-Cortázar I contributed to the histology, experimental design, in vivo treatment, statistical analysis and wrote the paper.
Correspondence to: Inma Castilla de Cortázar Larrea, MD, Department of Medical Physiology, School of Medicine, University CEU-USP, Boadilla del Monte, Madrid 28668, Spain. iccortazar@uma.es
Telephone: +34-91-3724765
Fax: +34-91-3724008
Received: November 1, 2007
Revised: February 16, 2008
Published online: May 7, 2008
Core Tip