Schnedl WJ, Piswanger-Soelkner C, Wallner SJ, Krause R, Lipp RW. Agenesis of the dorsal pancreas. World J Gastroenterol 2009; 15(3): 376-377 [PMID: 19140241 DOI: 10.3748/wjg.15.376]
Corresponding Author of This Article
Wolfgang J Schnedl, MD, Associate Professor of Medicine, Practice for General Internal Medicine, Hauptstrasse 5, A-8940 Liezen, Austria. w.schnedl@dr-schnedl.at
Article-Type of This Article
Letters To The Editor
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World J Gastroenterol. Jan 21, 2009; 15(3): 376-377 Published online Jan 21, 2009. doi: 10.3748/wjg.15.376
Agenesis of the dorsal pancreas
Wolfgang J Schnedl, Claudia Piswanger-Soelkner, Sandra J Wallner, Robert Krause, Rainer W Lipp
Wolfgang J Schnedl, Practice for General Internal Medicine, Hauptstrasse 5, A-8940 Liezen, Austria
Wolfgang J Schnedl, Claudia Piswanger-Soelkner, Robert Krause, Rainer W Lipp, Department of Internal Medicine, Medical University, Auenbruggerplatz 15, A-8036 Graz, Austria
Sandra J Wallner, Institute of Pathophysiology, Center for Molecular Medicine, Heinrichstrasse 31a, A-8010 Graz, Austria
Author contributions: Schnedl WJ, Lipp RW gave the conception and designed the letter; Schnedl WJ, Piswanger-Soelkner C analyzed and interpreted the data; Schnedl WJ drafted and critically revised the article for important intellectual content; Schnedl WJ, Wallner SJ, Lipp RW finally approved the article; Schnedl WJ, Piswanger-Soelkner C, Wallner SJ, Krause R, Lipp RW gave the administrative, technical, or logistic support; Wallner SJ, Krause R, Lipp RW collected and assembled the data.
Correspondence to: Wolfgang J Schnedl, MD, Associate Professor of Medicine, Practice for General Internal Medicine, Hauptstrasse 5, A-8940 Liezen, Austria. w.schnedl@dr-schnedl.at
Telephone: +43-3612-22833
Fax: +43-3612-22833-22
Received: July 6, 2008 Revised: December 23, 2008 Accepted: December 30, 2008 Published online: January 21, 2009
Abstract
During the last 100 years in medical literature, there are only 54 reports, including the report of Pasaoglu et al (World J Gastroenterol 2008; 14: 2915-2916), with clinical descriptions of agenesis of the dorsal pancreas in humans. Agenesis of the dorsal pancreas, a rare congenital pancreatic malformation, is associated with some other medical conditions such as hyperglycemia, abdominal pain, pancreatitis and a few other diseases. In approximately 50% of reported patients with this congenital malformation, hyperglycemia was demonstrated. Evaluation of hyperglycemia and diabetes mellitus in all patients with agenesis of the dorsal pancreas including description of fasting blood glucose, oral glucose tolerance test, glycated hemoglobin and medical treatment would be a future goal. Since autosomal dominant transmission has been suggested in single families, more family studies including imaging technologies with demonstration of the pancreatic duct system are needed for evaluation of this disease. With this letter to the editor, we aim to increase available information for the better understanding of this rare disease.
