Dr. Shogo Ohkoshi (born in Niigata,Japan, in Jan. 1959) graduated Niigata University school of medicine and obtained medical license in 1983. He majored in digestive organ disease as a physician. He first studied endoscopic diagnosis of early colorectal cancer at Akita red hospital in Japan. He collaborated with Dr. Shin-ei Kudo (Currently, horonary Professor of Showa University) helping him to find first depressed type of early colon cancer endoscopically , from where Dr Kudo established new diagnostic criteria of early colon cancer. Then, he studied molecular biology of hepatitis virus and cloned hepatitis C virus genome obtained from Japanese patients. This work was published in 1990 in Proc Natl Acad Sci as a coauthor with Dr Kato N and Dr Shimotohno K of Virology Division, National Cancer Institute of Japan. Then he worked on the transgenic mouse model of hepatitis C and hepatitis B virus and achieved some excellent studies using these models especially in the field of tissue tropism of HCV and hepatocarcinogenesis of HBV. Since then, as an associate professor of Gastroenterology division of Niigata University, he devoted himself to clinical practices for hepatitis patients and basic studies on viral hepatitis as well. His passion for studies was directed to the molecular mechanism of anti-hapatocarcinogenic effect of interferon that was the main anti-viral agents and clarified the mechanical association between the intracellular distribution of tumor suppressor such as p21 and interferon. He became professor of internal medicine, Nippon dental university in 2014 and head of Hospital in 2016.