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For: Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE. Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors. Br J Pharmacol 2020;177:1898-916. [PMID: 31881095 DOI: 10.1111/bph.14960] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 4.5] [Reference Citation Analysis]
Number Citing Articles
1 Hanke W, Patt J, Alenfelder J, Voss JH, Zdouc MM, Kehraus S, Kim JB, Grujičić GV, Namasivayam V, Reher R, Müller CE, Kostenis E, Crüsemann M, König GM. Feature-Based Molecular Networking for the Targeted Identification of Gq-Inhibiting FR900359 Derivatives. J Nat Prod 2021;84:1941-53. [PMID: 34197116 DOI: 10.1021/acs.jnatprod.1c00194] [Reference Citation Analysis]
2 Voss JH, Mahardhika AB, Inoue A, Müller CE. Agonist-Dependent Coupling of the Promiscuous Adenosine A2B Receptor to Gα Protein Subunits. ACS Pharmacol Transl Sci 2022;5:373-86. [PMID: 35592437 DOI: 10.1021/acsptsci.2c00020] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
3 Neumann A, Attah I, Al-hroub H, Namasivayam V, Müller CE. Discovery of P2Y 2 Receptor Antagonist Scaffolds through Virtual High-Throughput Screening. J Chem Inf Model . [DOI: 10.1021/acs.jcim.1c01235] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
4 Kuschak M, Schlegel JG, Schneider M, Kehraus S, Voss JH, Seidinger A, Matthey M, Wenzel D, Fleischmann BK, König GM, Müller CE. Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gαq Protein Inhibitors in Biological Samples. Front Chem 2020;8:833. [PMID: 33173765 DOI: 10.3389/fchem.2020.00833] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
5 Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE. Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors. Br J Pharmacol 2020;177:1898-916. [PMID: 31881095 DOI: 10.1111/bph.14960] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 4.5] [Reference Citation Analysis]
6 Lapadula D, Benovic JL. Targeting Oncogenic Gαq/11 in Uveal Melanoma. Cancers (Basel) 2021;13:6195. [PMID: 34944815 DOI: 10.3390/cancers13246195] [Reference Citation Analysis]
7 Hermes C, Richarz R, Wirtz DA, Patt J, Hanke W, Kehraus S, Voß JH, Küppers J, Ohbayashi T, Namasivayam V, Alenfelder J, Inoue A, Mergaert P, Gütschow M, Müller CE, Kostenis E, König GM, Crüsemann M. Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359. Nat Commun 2021;12:144. [PMID: 33420046 DOI: 10.1038/s41467-020-20418-3] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 9.0] [Reference Citation Analysis]
8 Kostenis E, Pfeil EM, Annala S. Heterotrimeric Gq proteins as therapeutic targets? J Biol Chem 2020;295:5206-15. [PMID: 32122969 DOI: 10.1074/jbc.REV119.007061] [Cited by in Crossref: 21] [Cited by in F6Publishing: 12] [Article Influence: 10.5] [Reference Citation Analysis]
9 Ma J, Weng L, Bastian BC, Chen X. Functional characterization of uveal melanoma oncogenes. Oncogene 2021;40:806-20. [PMID: 33262460 DOI: 10.1038/s41388-020-01569-5] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
10 Lim Y, Cho IT, Rennke HG, Cho G. β2-adrenergic receptor regulates ER-mitochondria contacts. Sci Rep 2021;11:21477. [PMID: 34728663 DOI: 10.1038/s41598-021-00801-w] [Reference Citation Analysis]
11 Patt J, Alenfelder J, Pfeil EM, Voss JH, Merten N, Eryilmaz F, Heycke N, Rick U, Inoue A, Kehraus S, Deupi X, Müller CE, König GM, Crüsemann M, Kostenis E. An experimental strategy to probe Gq contribution to signal transduction in living cells. J Biol Chem 2021;296:100472. [PMID: 33639168 DOI: 10.1016/j.jbc.2021.100472] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
12 Hermes C, König GM, Crüsemann M. The chromodepsins - chemistry, biology and biosynthesis of a selective Gq inhibitor natural product family. Nat Prod Rep 2021. [PMID: 33998635 DOI: 10.1039/d1np00005e] [Reference Citation Analysis]
13 Schlegel JG, Tahoun M, Seidinger A, Voss JH, Kuschak M, Kehraus S, Schneider M, Matthey M, Fleischmann BK, König GM, Wenzel D, Müller CE. Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation? ACS Pharmacol Transl Sci 2021;4:888-97. [PMID: 33860209 DOI: 10.1021/acsptsci.1c00021] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]