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For: Malfacini D, Patt J, Annala S, Harpsøe K, Eryilmaz F, Reher R, Crüsemann M, Hanke W, Zhang H, Tietze D, Gloriam DE, Bräuner-Osborne H, Strømgaard K, König GM, Inoue A, Gomeza J, Kostenis E. Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity. J Biol Chem 2019;294:5747-58. [PMID: 30745359 DOI: 10.1074/jbc.RA118.007250] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 7.3] [Reference Citation Analysis]
Number Citing Articles
1 Benkel T, Zimmermann M, Zeiner J, Bravo S, Merten N, Lim VJY, Matthees ESF, Drube J, Miess-tanneberg E, Malan D, Szpakowska M, Monteleone S, Grimes J, Koszegi Z, Lanoiselée Y, O’brien S, Pavlaki N, Dobberstein N, Inoue A, Nikolaev V, Calebiro D, Chevigné A, Sasse P, Schulz S, Hoffmann C, Kolb P, Waldhoer M, Simon K, Gomeza J, Kostenis E. How Carvedilol activates β2-adrenoceptors. Nat Commun 2022;13:7109. [DOI: 10.1038/s41467-022-34765-w] [Reference Citation Analysis]
2 Drube J, Haider RS, Matthees ESF, Reichel M, Zeiner J, Fritzwanker S, Ziegler C, Barz S, Klement L, Filor J, Weitzel V, Kliewer A, Miess-Tanneberg E, Kostenis E, Schulz S, Hoffmann C. GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation. Nat Commun 2022;13:540. [PMID: 35087057 DOI: 10.1038/s41467-022-28152-8] [Cited by in Crossref: 10] [Cited by in F6Publishing: 12] [Article Influence: 10.0] [Reference Citation Analysis]
3 Liu R, Liang L, Lacerda MP, Freed EF, Eckert CA. Advances in protein engineering and its application in synthetic biology. New Frontiers and Applications of Synthetic Biology 2022. [DOI: 10.1016/b978-0-12-824469-2.00013-0] [Reference Citation Analysis]
4 Bergkamp ND, Siderius M, Smit MJ. Pharmacology of Viral GPCRs: All-Round Chemokine Receptor Homologs. Comprehensive Pharmacology 2022. [DOI: 10.1016/b978-0-12-820472-6.00203-6] [Reference Citation Analysis]
5 Lapadula D, Benovic JL. Targeting Oncogenic Gαq/11 in Uveal Melanoma. Cancers (Basel) 2021;13:6195. [PMID: 34944815 DOI: 10.3390/cancers13246195] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
6 Hauser AS, Avet C, Normand C, Mancini A, Inoue A, Bouvier M, Gloriam DE. Common coupling map advances GPCR-G protein selectivity.. [DOI: 10.1101/2021.09.07.459250] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
7 Biringer RG. A review of non-prostanoid, eicosanoid receptors: expression, characterization, regulation, and mechanism of action. J Cell Commun Signal 2021. [PMID: 34173964 DOI: 10.1007/s12079-021-00630-6] [Reference Citation Analysis]
8 Patt J, Alenfelder J, Pfeil EM, Voss JH, Merten N, Eryilmaz F, Heycke N, Rick U, Inoue A, Kehraus S, Deupi X, Müller CE, König GM, Crüsemann M, Kostenis E. An experimental strategy to probe Gq contribution to signal transduction in living cells. J Biol Chem 2021;296:100472. [PMID: 33639168 DOI: 10.1016/j.jbc.2021.100472] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 9.0] [Reference Citation Analysis]
9 Drube J, Haider R, Matthees E, Reichel M, Zeiner J, Fritzwanker S, Ziegler C, Barz S, Klement L, Kliewer A, Miess E, Kostenis E, Schulz S, Hoffmann C. GRK2/3/5/6 knockout: The impact of individual GRKs on arrestin-binding and GPCR regulation.. [DOI: 10.1101/2021.02.12.430971] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
10 Hermes C, Richarz R, Wirtz DA, Patt J, Hanke W, Kehraus S, Voß JH, Küppers J, Ohbayashi T, Namasivayam V, Alenfelder J, Inoue A, Mergaert P, Gütschow M, Müller CE, Kostenis E, König GM, Crüsemann M. Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359. Nat Commun 2021;12:144. [PMID: 33420046 DOI: 10.1038/s41467-020-20418-3] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 19.0] [Reference Citation Analysis]
11 Ma J, Weng L, Bastian BC, Chen X. Functional characterization of uveal melanoma oncogenes. Oncogene 2021;40:806-20. [PMID: 33262460 DOI: 10.1038/s41388-020-01569-5] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 9.0] [Reference Citation Analysis]
12 Küppers J, Benkel T, Annala S, Kimura K, Reinelt L, Fleischmann BK, Kostenis E, Gütschow M. Tetrahydroimidazo[1,2-a]pyrazine Derivatives: Synthesis and Evaluation as Gαq -Protein Ligands. Chemistry 2020;26:12615-23. [PMID: 32428383 DOI: 10.1002/chem.202001446] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 2.5] [Reference Citation Analysis]
13 Boesgaard MW, Harpsøe K, Malmberg M, Underwood CR, Inoue A, Mathiesen JM, König GM, Kostenis E, Gloriam DE, Bräuner-Osborne H. Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs. J Biol Chem 2020;295:13850-61. [PMID: 32753482 DOI: 10.1074/jbc.RA120.013002] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
14 Meyrath M, Szpakowska M, Zeiner J, Massotte L, Merz MP, Benkel T, Simon K, Ohnmacht J, Turner JD, Krüger R, Seutin V, Ollert M, Kostenis E, Chevigné A. The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides. Nat Commun 2020;11:3033. [PMID: 32561830 DOI: 10.1038/s41467-020-16664-0] [Cited by in Crossref: 43] [Cited by in F6Publishing: 46] [Article Influence: 21.5] [Reference Citation Analysis]
15 Kostenis E, Pfeil EM, Annala S. Heterotrimeric Gq proteins as therapeutic targets? J Biol Chem 2020;295:5206-15. [PMID: 32122969 DOI: 10.1074/jbc.REV119.007061] [Cited by in Crossref: 31] [Cited by in F6Publishing: 31] [Article Influence: 15.5] [Reference Citation Analysis]