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For: Yu Z, Ku AF, Anglin JL, Sharma R, Ucisik MN, Faver JC, Li F, Nyshadham P, Simmons N, Sharma KL, Nagarajan S, Riehle K, Kaur G, Sankaran B, Storl-Desmond M, Palmer SS, Young DW, Kim C, Matzuk MM. Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proc Natl Acad Sci U S A 2021;118:e2021102118. [PMID: 33637650 DOI: 10.1073/pnas.2021102118] [Cited by in Crossref: 18] [Cited by in F6Publishing: 20] [Article Influence: 9.0] [Reference Citation Analysis]
Number Citing Articles
1 Barros EP, Ries B, Champion C, Rieder SR, Riniker S. Accounting for Solvation Correlation Effects on the Thermodynamics of Water Networks in Protein Cavities. J Chem Inf Model 2023. [PMID: 36917685 DOI: 10.1021/acs.jcim.2c01610] [Reference Citation Analysis]
2 Tan Z, Garcia TX. SLO3 in the fast lane: The latest male contraceptive target with a promising small-molecule inhibitor. Proc Natl Acad Sci U S A 2023;120:e2221758120. [PMID: 36791103 DOI: 10.1073/pnas.2221758120] [Reference Citation Analysis]
3 He H, Ding T, Zhang T, Geng W, Xu J, Wei Y, Zhai J. BDE-209 disturbed proliferation and differentiation of spermatogonia during mitotic process through estrogen receptor α. Reprod Biol 2023;23:100737. [PMID: 36821943 DOI: 10.1016/j.repbio.2023.100737] [Reference Citation Analysis]
4 Tong JB, Xiao XC, Luo D, Xu HY, Xing YC, Gao P, Liu Y. Discovery of novel BRD4-BD2 inhibitors via in silico approaches: QSAR techniques, molecular docking, and molecular dynamics simulations. Mol Divers 2023. [PMID: 36773087 DOI: 10.1007/s11030-023-10611-z] [Reference Citation Analysis]
5 Chen C, Lu T, Chen P, Li Z, Yang Y, Fan S, Zhang Y, Chen K, Fu W, Wang Y, Luo C, Zhou B. Cyclization strategy leads to highly potent Bromodomain and extra-terminal (BET) Bromodomain inhibitors for the treatment of acute liver injury. Eur J Med Chem 2023;247:115023. [PMID: 36566713 DOI: 10.1016/j.ejmech.2022.115023] [Reference Citation Analysis]
6 Suo Y, Xu M, Sun M, Lu W, Wang X, Lu X. Ruthenium-Mediated [2 + 2 + 2] Cyclization: A Route to Forge Indane and Isoindoline Core and Its Application in DNA-Encoded Library Technology. Org Lett 2022. [DOI: 10.1021/acs.orglett.2c03759] [Reference Citation Analysis]
7 Oura S, Mori H, Ikawa M. Genome editing in mice and its application to the study of spermatogenesis. Gene and Genome Editing 2022;3-4:100014. [DOI: 10.1016/j.ggedit.2022.100014] [Reference Citation Analysis]
8 Opo FADM, Alkarim S, Alrefaei GI, Molla MHR, Alsubhi NH, Alzahrani F, Ahammad F. Pharmacophore-Model-Based Virtual-Screening Approaches Identified Novel Natural Molecular Candidates for Treating Human Neuroblastoma. Curr Issues Mol Biol 2022;44:4838-58. [PMID: 36286044 DOI: 10.3390/cimb44100329] [Reference Citation Analysis]
9 Wu S, Li X, Shang L, Wu L, Li T, Li P, Ji Z, Hou J, Yin M, Xu W. The novel BRDT inhibitor NHWD870 shows potential as a male contraceptive in mice. Acta Biochim Biophys Sin (Shanghai) 2022;54:1789-800. [PMID: 36239350 DOI: 10.3724/abbs.2022135] [Reference Citation Analysis]
10 Jiang J, Zhao PL, Sigua LH, Chan A, Schönbrunn E, Qi J, Georg GI. 1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains. Arch Pharm (Weinheim) 2022;:e2200288. [PMID: 35941525 DOI: 10.1002/ardp.202200288] [Reference Citation Analysis]
11 Norcross NR, Georgiou I, Johnston ZC, Gruber FS, Swedlow JR, Read KD, Barratt CL, Gilbert IH. Male contraceptive development: A medicinal chemistry perspective. European Journal of Medicinal Chemistry 2022. [DOI: 10.1016/j.ejmech.2022.114709] [Reference Citation Analysis]
12 Guan X, Cheryala N, Karim RM, Chan A, Berndt N, Qi J, Georg GI, Schönbrunn E. Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J Med Chem 2022. [PMID: 35867655 DOI: 10.1021/acs.jmedchem.2c00453] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
13 Modukuri RK, Yu Z, Tan Z, Ta HM, Ucisik MN, Jin Z, Anglin JL, Sharma KL, Nyshadham P, Li F, Riehle K, Faver JC, Duong K, Nagarajan S, Simmons N, Palmer SS, Teng M, Young DW, Yi JS, Kim C, Matzuk MM. Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections. Proc Natl Acad Sci U S A 2022;119:e2122506119. [PMID: 35622893 DOI: 10.1073/pnas.2122506119] [Reference Citation Analysis]
14 Shen Y, Yang G, Huang W, Shaginian A, Lin Q, Wan J, Li J, Deng Y, Liu G. Photoredox Deaminative Alkylation in DNA-Encoded Library Synthesis. Org Lett 2022. [PMID: 35362987 DOI: 10.1021/acs.orglett.2c00697] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 5.0] [Reference Citation Analysis]
15 Li J, Zhang C, Xu H, Wang C, Dong R, Shen H, Zhuang X, Chen X, Li Q, Lu J, Zhang M, Wu X, Loomes KM, Zhou Y, Zhang Y, Liu J, Xu Y. Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors. J Med Chem 2022. [PMID: 35333526 DOI: 10.1021/acs.jmedchem.2c00100] [Reference Citation Analysis]
16 Cui H, Divakaran A, Hoell ZJ, Ellingson MO, Scholtz CR, Zahid H, Johnson JA, Griffith EC, Gee CT, Lee AL, Khanal S, Shi K, Aihara H, Shah VH, Lee RE, Harki DA, Pomerantz WCK. A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem 2022. [PMID: 35007061 DOI: 10.1021/acs.jmedchem.1c01779] [Cited by in Crossref: 8] [Cited by in F6Publishing: 12] [Article Influence: 8.0] [Reference Citation Analysis]
17 Jiang J, Sigua LH, Chan A, Kalra P, Pomerantz WCK, Schönbrunn E, Qi J, Georg GI. Dihydropyridine Lactam Analogs Targeting BET Bromodomains. ChemMedChem 2022;17:e202100407. [PMID: 34932262 DOI: 10.1002/cmdc.202100407] [Reference Citation Analysis]
18 Karim RM, Bikowitz MJ, Chan A, Zhu JY, Grassie D, Becker A, Berndt N, Gunawan S, Lawrence NJ, Schönbrunn E. Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors. J Med Chem 2021;64:15772-86. [PMID: 34710325 DOI: 10.1021/acs.jmedchem.1c01096] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 2.5] [Reference Citation Analysis]
19 Zhang J, Li X, Wei H, Li Y, Zhang G, Li Y. Sequential DNA-Encoded Building Block Fusion for the Construction of Polysubstituted Pyrazoline Core Libraries. Org Lett 2021;23:8429-33. [PMID: 34652930 DOI: 10.1021/acs.orglett.1c03145] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 5.0] [Reference Citation Analysis]
20 Chamakuri S, Chung MK, Samuel ELG, Tran KA, Chen YC, Nyshadham P, Santini C, Matzuk MM, Young DW. Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library. Bioorg Med Chem 2021;48:116387. [PMID: 34571488 DOI: 10.1016/j.bmc.2021.116387] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
21 Chamakuri S, Lu S, Ucisik MN, Bohren KM, Chen YC, Du HC, Faver JC, Jimmidi R, Li F, Li JY, Nyshadham P, Palmer SS, Pollet J, Qin X, Ronca SE, Sankaran B, Sharma KL, Tan Z, Versteeg L, Yu Z, Matzuk MM, Palzkill T, Young DW. DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors. Proc Natl Acad Sci U S A 2021;118:e2111172118. [PMID: 34426525 DOI: 10.1073/pnas.2111172118] [Cited by in Crossref: 11] [Cited by in F6Publishing: 14] [Article Influence: 5.5] [Reference Citation Analysis]
22 Zhou Y, Shen W, Peng J, Deng Y, Li X. Identification of isoform/domain-selective fragments from the selection of DNA-encoded dynamic library. Bioorg Med Chem 2021;45:116328. [PMID: 34364223 DOI: 10.1016/j.bmc.2021.116328] [Cited by in Crossref: 8] [Cited by in F6Publishing: 9] [Article Influence: 4.0] [Reference Citation Analysis]
23 Zhang G, Zhang J, Gao Y, Li Y, Li Y. Strategies for targeting undruggable targets. Expert Opin Drug Discov 2021;:1-15. [PMID: 34455870 DOI: 10.1080/17460441.2021.1969359] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 3.5] [Reference Citation Analysis]
24 Boyson SP, Gao C, Quinn K, Boyd J, Paculova H, Frietze S, Glass KC. Functional Roles of Bromodomain Proteins in Cancer. Cancers (Basel) 2021;13:3606. [PMID: 34298819 DOI: 10.3390/cancers13143606] [Cited by in Crossref: 7] [Cited by in F6Publishing: 9] [Article Influence: 3.5] [Reference Citation Analysis]
25 Rianjongdee F, Atkinson SJ, Chung CW, Grandi P, Gray JRJ, Kaushansky LJ, Medeiros P, Messenger C, Phillipou A, Preston A, Prinjha RK, Rioja I, Satz AL, Taylor S, Wall ID, Watson RJ, Yao G, Demont EH. Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit. J Med Chem 2021;64:10806-33. [PMID: 34251219 DOI: 10.1021/acs.jmedchem.1c00412] [Cited by in Crossref: 15] [Cited by in F6Publishing: 18] [Article Influence: 7.5] [Reference Citation Analysis]
26 Wu R, Du T, Sun W, Shaginian A, Gao S, Li J, Wan J, Liu G. Functionalization of DNA-Tagged Alkenes Enabled by Visible-Light-Induced C–H Activation of N -Aryl Tertiary Amines. Org Lett 2021;23:3486-90. [DOI: 10.1021/acs.orglett.1c00924] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 5.0] [Reference Citation Analysis]