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For: Soya S, Takahashi TM, McHugh TJ, Maejima T, Herlitze S, Abe M, Sakimura K, Sakurai T. Orexin modulates behavioral fear expression through the locus coeruleus. Nat Commun 2017;8:1606. [PMID: 29151577 DOI: 10.1038/s41467-017-01782-z] [Cited by in Crossref: 47] [Cited by in F6Publishing: 39] [Article Influence: 9.4] [Reference Citation Analysis]
Number Citing Articles
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6 Nakajo H, Chou MY, Kinoshita M, Appelbaum L, Shimazaki H, Tsuboi T, Okamoto H. Hunger Potentiates the Habenular Winner Pathway for Social Conflict by Orexin-Promoted Biased Alternative Splicing of the AMPA Receptor Gene. Cell Rep 2020;31:107790. [PMID: 32579920 DOI: 10.1016/j.celrep.2020.107790] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 7.0] [Reference Citation Analysis]
7 Koorneef LL, Bogaards M, Reinders MJT, Meijer OC, Mahfouz A. How Metabolic State May Regulate Fear: Presence of Metabolic Receptors in the Fear Circuitry. Front Neurosci 2018;12:594. [PMID: 30210279 DOI: 10.3389/fnins.2018.00594] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
8 Han D, Shi Y, Han F. The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder. J Comp Neurol 2022;530:592-606. [PMID: 34387361 DOI: 10.1002/cne.25231] [Reference Citation Analysis]
9 Li S, Franken P, Vassalli A. Bidirectional and context-dependent changes in theta and gamma oscillatory brain activity in noradrenergic cell-specific Hypocretin/Orexin receptor 1-KO mice. Sci Rep 2018;8:15474. [PMID: 30341359 DOI: 10.1038/s41598-018-33069-8] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.8] [Reference Citation Analysis]
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11 Shiozaki K, Kawabe M, Karasuyama K, Kurachi T, Hayashi A, Ataka K, Iwai H, Takeno H, Hayasaka O, Kotani T, Komatsu M, Inui A. Neuropeptide Y deficiency induces anxiety-like behaviours in zebrafish (Danio rerio). Sci Rep 2020;10:5913. [PMID: 32246073 DOI: 10.1038/s41598-020-62699-0] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
12 Faesel N, Kolodziejczyk MH, Koch M, Fendt M. Orexin deficiency affects sociability and the acquisition, expression, and extinction of conditioned social fear. Brain Res 2021;1751:147199. [PMID: 33160959 DOI: 10.1016/j.brainres.2020.147199] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
13 Salehabadi S, Abrari K, Elahdadi Salmani M, Nasiri M, Lashkarbolouki T. Investigating the role of the amygdala orexin receptor 1 in memory acquisition and extinction in a rat model of PTSD. Behavioural Brain Research 2020;384:112455. [DOI: 10.1016/j.bbr.2019.112455] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
14 Delic V, Ratliff WA, Citron BA. Sleep Deprivation, a Link Between Post-Traumatic Stress Disorder and Alzheimer's Disease. J Alzheimers Dis 2021;79:1443-9. [PMID: 33459652 DOI: 10.3233/JAD-201378] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
15 Pan YP, Liu C, Liu MF, Wang Y, Bian K, Xue Y, Chen L. Involvement of orexin-A in the regulation of neuronal activity and emotional behaviors in central amygdala in rats. Neuropeptides 2020;80:102019. [PMID: 31980205 DOI: 10.1016/j.npep.2020.102019] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
16 Lustberg D, Tillage RP, Bai Y, Pruitt M, Liles LC, Weinshenker D. Noradrenergic circuits in the forebrain control affective responses to novelty. Psychopharmacology (Berl) 2020;237:3337-55. [PMID: 32821984 DOI: 10.1007/s00213-020-05615-8] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 2.5] [Reference Citation Analysis]
17 Likhtik E, Johansen JP. Neuromodulation in circuits of aversive emotional learning. Nat Neurosci 2019;22:1586-97. [PMID: 31551602 DOI: 10.1038/s41593-019-0503-3] [Cited by in Crossref: 32] [Cited by in F6Publishing: 25] [Article Influence: 10.7] [Reference Citation Analysis]
18 Soya S, Sakurai T. Orexin as a modulator of fear-related behavior: Hypothalamic control of noradrenaline circuit. Brain Res 2020;1731:146037. [PMID: 30481504 DOI: 10.1016/j.brainres.2018.11.032] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 3.8] [Reference Citation Analysis]
19 Xu H, Liu L, Tian Y, Wang J, Li J, Zheng J, Zhao H, He M, Xu TL, Duan S, Xu H. A Disinhibitory Microcircuit Mediates Conditioned Social Fear in the Prefrontal Cortex. Neuron 2019;102:668-682.e5. [PMID: 30898376 DOI: 10.1016/j.neuron.2019.02.026] [Cited by in Crossref: 51] [Cited by in F6Publishing: 46] [Article Influence: 17.0] [Reference Citation Analysis]
20 Agee LA, Nemchek V, Malone CA, Lee HJ, Monfils MH. Appetitive Behavior in the Social Transmission of Food Preference Paradigm Predicts Activation of Orexin-A producing Neurons in a Sex-Dependent Manner. Neuroscience 2022;481:30-46. [PMID: 34843892 DOI: 10.1016/j.neuroscience.2021.11.032] [Reference Citation Analysis]
21 Shibano N, Yamazaki M, Arima T, Abe K, Kuroda M, Kobayashi Y, Itohara S, Furuichi T, Sano Y. Excitation of prefrontal cortical neurons during conditioning enhances fear memory formation. Sci Rep 2020;10:8613. [PMID: 32451463 DOI: 10.1038/s41598-020-65597-7] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
22 Caldirola D, Alciati A, Cuniberti F, Perna G. Experimental Drugs for Panic Disorder: An Updated Systematic Review. J Exp Pharmacol 2021;13:441-59. [PMID: 33889031 DOI: 10.2147/JEP.S261403] [Reference Citation Analysis]
23 Sato T, Yajima T, Fujita M, Kobashi M, Ichikawa H, Yoshida R, Mitoh Y. Orexin A and B in the rat superior salivatory nucleus. Auton Neurosci 2020;228:102712. [PMID: 32721850 DOI: 10.1016/j.autneu.2020.102712] [Reference Citation Analysis]
24 Hopf FW. Recent perspectives on orexin/hypocretin promotion of addiction-related behaviors. Neuropharmacology 2020;168:108013. [PMID: 32092435 DOI: 10.1016/j.neuropharm.2020.108013] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 9.5] [Reference Citation Analysis]
25 Kaplan GB, Lakis GA, Zhoba H. Sleep-Wake and Arousal Dysfunctions in Post-Traumatic Stress Disorder:Role of Orexin Systems. Brain Res Bull 2022:S0361-9230(22)00121-6. [PMID: 35618150 DOI: 10.1016/j.brainresbull.2022.05.006] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
26 Gottschalk MG, Richter J, Ziegler C, Schiele MA, Mann J, Geiger MJ, Schartner C, Homola GA, Alpers GW, Büchel C, Fehm L, Fydrich T, Gerlach AL, Gloster AT, Helbig-Lang S, Kalisch R, Kircher T, Lang T, Lonsdorf TB, Pané-Farré CA, Ströhle A, Weber H, Zwanzger P, Arolt V, Romanos M, Wittchen HU, Hamm A, Pauli P, Reif A, Deckert J, Neufang S, Höfler M, Domschke K. Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes. Transl Psychiatry 2019;9:75. [PMID: 30718541 DOI: 10.1038/s41398-019-0415-8] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 4.0] [Reference Citation Analysis]
27 Fernández de Sevilla ME, Pignatelli J, Zegarra-Valdivia JA, Mendez P, Nuñez A, Torres Alemán I. Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons. Mol Psychiatry 2022. [PMID: 35115701 DOI: 10.1038/s41380-022-01442-9] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
28 Sanacora G, Yan Z, Popoli M. The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders. Nat Rev Neurosci 2021. [PMID: 34893785 DOI: 10.1038/s41583-021-00540-x] [Reference Citation Analysis]
29 Montagrin A, Martins-Klein B, Sander D, Mather M. Effects of hunger on emotional arousal responses and attention/memory biases. Emotion 2021;21:148-58. [PMID: 31589063 DOI: 10.1037/emo0000680] [Cited by in Crossref: 1] [Article Influence: 0.3] [Reference Citation Analysis]
30 Wan L, Xu F, Liu C, Ji B, Zhang R, Wang P, Wu F, Pan Y, Yang C, Wang C, Chen J. Transmembrane peptide 4 and 5 of APJ are essential for its heterodimerization with OX1R. Biochemical and Biophysical Research Communications 2020;521:408-13. [DOI: 10.1016/j.bbrc.2019.10.146] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
31 Bostanciklioğlu M. Neuromodulation of Memory Formation and Extinction. Curr Neurovasc Res 2020;17:319-26. [PMID: 32316891 DOI: 10.2174/1567202617999200421202818] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
32 Goadsby PJ, Holland PR. An Update: Pathophysiology of Migraine. Neurol Clin 2019;37:651-71. [PMID: 31563225 DOI: 10.1016/j.ncl.2019.07.008] [Cited by in Crossref: 39] [Cited by in F6Publishing: 25] [Article Influence: 19.5] [Reference Citation Analysis]
33 Yaeger JDW, Krupp KT, Summers TR, Summers CH. Contextual generalization of social stress learning is modulated by orexin receptors in basolateral amygdala. Neuropharmacology 2022;215:109168. [PMID: 35724928 DOI: 10.1016/j.neuropharm.2022.109168] [Reference Citation Analysis]
34 Peleg-Raibstein D, Burdakov D. Do orexin/hypocretin neurons signal stress or reward? Peptides 2021;145:170629. [PMID: 34416308 DOI: 10.1016/j.peptides.2021.170629] [Reference Citation Analysis]
35 Shen YC, Sun X, Li L, Zhang HY, Huang ZL, Wang YQ. Roles of Neuropeptides in Sleep-Wake Regulation. Int J Mol Sci 2022;23:4599. [PMID: 35562990 DOI: 10.3390/ijms23094599] [Reference Citation Analysis]
36 Malikowska-Racia N, Salat K. Recent advances in the neurobiology of posttraumatic stress disorder: A review of possible mechanisms underlying an effective pharmacotherapy. Pharmacol Res 2019;142:30-49. [PMID: 30742899 DOI: 10.1016/j.phrs.2019.02.001] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 3.3] [Reference Citation Analysis]
37 Li SB, de Lecea L. The hypocretin (orexin) system: from a neural circuitry perspective. Neuropharmacology 2020;167:107993. [PMID: 32135427 DOI: 10.1016/j.neuropharm.2020.107993] [Cited by in Crossref: 29] [Cited by in F6Publishing: 25] [Article Influence: 14.5] [Reference Citation Analysis]
38 Saito YC, Tsujino N, Abe M, Yamazaki M, Sakimura K, Sakurai T. Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture. Front Neurosci 2018;12:892. [PMID: 30555297 DOI: 10.3389/fnins.2018.00892] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 2.5] [Reference Citation Analysis]
39 Zhao S, Wang S, Li H, Guo J, Li J, Wang D, Zhang X, Yin L, Li R, Li A, Li H, Fan Z, Yang Q, Zhong H, Dong H. Activation of Orexinergic Neurons Inhibits the Anesthetic Effect of Desflurane on Consciousness State via Paraventricular Thalamic Nucleus in Rats. Anesth Analg 2021;133:781-93. [PMID: 34403389 DOI: 10.1213/ANE.0000000000005651] [Reference Citation Analysis]
40 Yamashita A, Moriya S, Nishi R, Kaminosono J, Yamanaka A, Kuwaki T. Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice. Mol Brain 2021;14:104. [PMID: 34193206 DOI: 10.1186/s13041-021-00818-2] [Reference Citation Analysis]
41 Olsen N, Furlong TM, Carrive P. Behavioural and cardiovascular effects of orexin-A infused into the central amygdala under basal and fear conditions in rats. Behav Brain Res 2021;415:113515. [PMID: 34371088 DOI: 10.1016/j.bbr.2021.113515] [Reference Citation Analysis]
42 Kawabe M, Hayashi A, Komatsu M, Inui A, Shiozaki K. Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish. Neuropeptides 2021;87:102136. [PMID: 33721592 DOI: 10.1016/j.npep.2021.102136] [Reference Citation Analysis]
43 Kuwano N, Kato TA, Mitsuhashi M, Sato-Kasai M, Shimokawa N, Hayakawa K, Ohgidani M, Sagata N, Kubo H, Sakurai T, Kanba S. Neuron-related blood inflammatory markers as an objective evaluation tool for major depressive disorder: An exploratory pilot case-control study. J Affect Disord 2018;240:88-98. [PMID: 30059939 DOI: 10.1016/j.jad.2018.07.040] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 5.0] [Reference Citation Analysis]
44 Asok A, Kandel ER, Rayman JB. The Neurobiology of Fear Generalization. Front Behav Neurosci 2018;12:329. [PMID: 30697153 DOI: 10.3389/fnbeh.2018.00329] [Cited by in Crossref: 41] [Cited by in F6Publishing: 36] [Article Influence: 13.7] [Reference Citation Analysis]
45 Quinlan MAL, Strong VM, Skinner DM, Martin GM, Harley CW, Walling SG. Locus Coeruleus Optogenetic Light Activation Induces Long-Term Potentiation of Perforant Path Population Spike Amplitude in Rat Dentate Gyrus. Front Syst Neurosci 2018;12:67. [PMID: 30687027 DOI: 10.3389/fnsys.2018.00067] [Cited by in Crossref: 6] [Cited by in F6Publishing: 8] [Article Influence: 2.0] [Reference Citation Analysis]
46 Dustrude ET, Caliman IF, Bernabe CS, Fitz SD, Grafe LA, Bhatnagar S, Bonaventure P, Johnson PL, Molosh AI, Shekhar A. Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear. Front Neurosci 2018;12:934. [PMID: 30618563 DOI: 10.3389/fnins.2018.00934] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 4.8] [Reference Citation Analysis]
47 Recinella L, Chiavaroli A, Ferrante C, Mollica A, Macedonio G, Stefanucci A, Dimmito MP, Dvorácskó S, Tömböly C, Brunetti L, Orlando G, Leone S. Effects of central RVD-hemopressin(α) administration on anxiety, feeding behavior and hypothalamic neuromodulators in the rat. Pharmacological Reports 2018;70:650-7. [DOI: 10.1016/j.pharep.2018.01.010] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 4.0] [Reference Citation Analysis]
48 Soya S, Sakurai T. Evolution of Orexin Neuropeptide System: Structure and Function. Front Neurosci 2020;14:691. [PMID: 32754010 DOI: 10.3389/fnins.2020.00691] [Cited by in Crossref: 13] [Cited by in F6Publishing: 14] [Article Influence: 6.5] [Reference Citation Analysis]
49 Hou Y, Liu Y, Liu C, Yan Z, Ma Q, Chen J, Zhang M, Yan Q, Li X, Chen J. Xiaoyaosan regulates depression‐related behaviors with physical symptoms by modulating Orexin A/OxR1 in the hypothalamus. Anat Rec 2020;303:2144-53. [DOI: 10.1002/ar.24386] [Cited by in Crossref: 4] [Cited by in F6Publishing: 6] [Article Influence: 2.0] [Reference Citation Analysis]
50 Saito YC, Tsujino N, Abe M, Yamazaki M, Sakimura K, Sakurai T. Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture. Front Neurosci 2018;12:892. [PMID: 30555297 DOI: 10.3389/fnins.2018.00892] [Cited by in F6Publishing: 1] [Reference Citation Analysis]