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For: Yang D, Zhou Q, Labroska V, Qin S, Darbalaei S, Wu Y, Yuliantie E, Xie L, Tao H, Cheng J, Liu Q, Zhao S, Shui W, Jiang Y, Wang MW. G protein-coupled receptors: structure- and function-based drug discovery. Signal Transduct Target Ther 2021;6:7. [PMID: 33414387 DOI: 10.1038/s41392-020-00435-w] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 11.0] [Reference Citation Analysis]
Number Citing Articles
1 Panchal D, Bhagwat S, Parte P. N-Formyl-L-aspartate mediates chemotaxis in sperm via the beta-2-adrenergic receptor. Front Cell Dev Biol 2022;10:959094. [DOI: 10.3389/fcell.2022.959094] [Reference Citation Analysis]
2 Schlichting M, Richhariya S, Herndon N, Ma D, Xin J, Lenh W, Abruzzi K, Rosbash M. Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep. Proc Natl Acad Sci U S A 2022;119:e2206066119. [PMID: 35969763 DOI: 10.1073/pnas.2206066119] [Reference Citation Analysis]
3 Lee C, Su BH, Tseng YJ. Comparative studies of AlphaFold, RoseTTAFold and Modeller: a case study involving the use of G-protein-coupled receptors. Brief Bioinform 2022:bbac308. [PMID: 35945035 DOI: 10.1093/bib/bbac308] [Reference Citation Analysis]
4 Singh D, Kaur L, Rahman AJ, Singh P, Kumar Tiwari A, Ojha H. Binding and mechanistic studies of 5-HT7 specific benzothiazolone derivatives with Bovine Serum Albumin: Spectroscopic and In silico studies. Journal of Molecular Liquids 2022. [DOI: 10.1016/j.molliq.2022.120143] [Reference Citation Analysis]
5 He XH, You CZ, Jiang HL, Jiang Y, Xu HE, Cheng X. AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors. Acta Pharmacol Sin 2022. [PMID: 35778488 DOI: 10.1038/s41401-022-00938-y] [Reference Citation Analysis]
6 Putt KS, Du Y, Fu H, Zhang Z. High-throughput screening strategies for space-based radiation countermeasure discovery. Life Sciences in Space Research 2022. [DOI: 10.1016/j.lssr.2022.07.004] [Reference Citation Analysis]
7 Hasan MR, Alsaiari AA, Fakhurji BZ, Molla MHR, Asseri AH, Sumon MAA, Park MN, Ahammad F, Kim B. Application of Mathematical Modeling and Computational Tools in the Modern Drug Design and Development Process. Molecules 2022;27:4169. [DOI: 10.3390/molecules27134169] [Reference Citation Analysis]
8 Kim DH, Park JC, Lee JS. G protein-coupled receptors (GPCRs) in rotifers and cladocerans: Potential applications in ecotoxicology, ecophysiology, comparative endocrinology, and pharmacology. Comp Biochem Physiol C Toxicol Pharmacol 2022;256:109297. [PMID: 35183764 DOI: 10.1016/j.cbpc.2022.109297] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
9 Mackiewicz T, Jacenik D, Talar M, Fichna J. The GPR35 expression pattern is associated with overall survival in male patients with colorectal cancer. Pharmacol Rep 2022. [PMID: 35622222 DOI: 10.1007/s43440-022-00371-2] [Reference Citation Analysis]
10 Jakubec D, Skoda P, Krivak R, Novotny M, Hoksza D. PrankWeb 3: accelerated ligand-binding site predictions for experimental and modelled protein structures. Nucleic Acids Res 2022:gkac389. [PMID: 35609995 DOI: 10.1093/nar/gkac389] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
11 Sakellakis M. Orphan receptors in prostate cancer. Prostate 2022. [PMID: 35538397 DOI: 10.1002/pros.24370] [Reference Citation Analysis]
12 Bayrak A, Hanson J, Laufer S, Pillaiyar T. Super-conserved receptors expressed in the brain: biology and medicinal chemistry efforts. Future Med Chem 2022. [PMID: 35535715 DOI: 10.4155/fmc-2022-0006] [Reference Citation Analysis]
13 Heo L, Feig M. Multi-state modeling of G-protein coupled receptors at experimental accuracy. Proteins 2022. [PMID: 35510704 DOI: 10.1002/prot.26382] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 3.0] [Reference Citation Analysis]
14 Liu L, Wilcox XE, Fisher AJ, Boyd SD, Zhi J, Winkler DD, Bulla LA Jr. Functional and Structural Analysis of the Toxin-Binding Site of the Cadherin G-Protein-Coupled Receptor, BT-R1, for Cry1A Toxins of Bacillus thuringiensis. Biochemistry 2022. [PMID: 35438971 DOI: 10.1021/acs.biochem.2c00089] [Reference Citation Analysis]
15 Mueller J, Tescarollo FC, Sun H. DREADDs in Epilepsy Research: Network-Based Review. Front Mol Neurosci 2022;15:863003. [DOI: 10.3389/fnmol.2022.863003] [Reference Citation Analysis]
16 Egyed A, Kiss DJ, Keserű GM. The Impact of the Secondary Binding Pocket on the Pharmacology of Class A GPCRs. Front Pharmacol 2022;13:847788. [PMID: 35355719 DOI: 10.3389/fphar.2022.847788] [Reference Citation Analysis]
17 Cheng H, Guo P, Su T, Jiang C, Zhu Z, Wei W, Zhang L, Wang Q. G protein-coupled receptor kinase type 2 and β-arrestin2: Key players in immune cell functions and inflammation. Cellular Signalling 2022. [DOI: 10.1016/j.cellsig.2022.110337] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
18 Dubovski N, Ben Shoshan-Galeczki Y, Malach E, Niv MY. Taste and chirality: l-glucose sweetness is mediated by TAS1R2/TAS2R3 receptor. Food Chem 2022;373:131393. [PMID: 34715629 DOI: 10.1016/j.foodchem.2021.131393] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
19 Raines R, Mcknight I, White H, Legg K, Lee C, Li W, Lee PHU, Shim JW. Drug-Targeted Genomes: Mutability of Ion Channels and GPCRs. Biomedicines 2022;10:594. [DOI: 10.3390/biomedicines10030594] [Reference Citation Analysis]
20 Bu Y, Hu Q, Bao T, Xie X, Wang S. Recent advances in cell membrane-coated technology for drug discovery from natural products. TrAC Trends in Analytical Chemistry 2022. [DOI: 10.1016/j.trac.2022.116601] [Cited by in Crossref: 2] [Article Influence: 2.0] [Reference Citation Analysis]
21 El-atawneh S, Goldblum A. Candidate Therapeutics by Screening for Multitargeting Ligands: Combining the CB2 Receptor With CB1, PPARγ and 5-HT4 Receptors. Front Pharmacol 2022;13:812745. [DOI: 10.3389/fphar.2022.812745] [Reference Citation Analysis]
22 Zhao F, Zhou Q, Cong Z, Hang K, Zou X, Zhang C, Chen Y, Dai A, Liang A, Ming Q, Wang M, Chen LN, Xu P, Chang R, Feng W, Xia T, Zhang Y, Wu B, Yang D, Zhao L, Xu HE, Wang MW. Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun 2022;13:1057. [PMID: 35217653 DOI: 10.1038/s41467-022-28683-0] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 4.0] [Reference Citation Analysis]
23 Mercier V, Boucher G, Devost D, Bourque K, Alikashani A, Beauchamp C, Bitton A, Foisy S, Goyette P, Charron G, Hébert TE, Rioux JD. IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation. Cell Signal 2022;:110294. [PMID: 35218908 DOI: 10.1016/j.cellsig.2022.110294] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
24 Barreca M, Spanò V, Raimondi MV, Bivacqua R, Giuffrida S, Montalbano A, Cavalli A, Bertoni F, Barraja P. GPCR Inhibition in Treating Lymphoma. ACS Med Chem Lett 2022;13:358-64. [DOI: 10.1021/acsmedchemlett.1c00600] [Cited by in Crossref: 7] [Article Influence: 7.0] [Reference Citation Analysis]
25 Khoury M, Cohen I, Bar-sela G. “The Two Sides of the Same Coin”—Medical Cannabis, Cannabinoids and Immunity: Pros and Cons Explained. Pharmaceutics 2022;14:389. [DOI: 10.3390/pharmaceutics14020389] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
26 Jarończyk M, Walory J. Novel Molecular Targets of Antidepressants. Molecules 2022;27:533. [PMID: 35056845 DOI: 10.3390/molecules27020533] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
27 Spezani R, Mandarim-de-Lacerda CA. The current significance and prospects for the use of dual receptor agonism GLP-1/Glucagon. Life Sci 2022;288:120188. [PMID: 34861287 DOI: 10.1016/j.lfs.2021.120188] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 5.0] [Reference Citation Analysis]
28 Kim H, Park I, Park S, Yang H, Jeong D, Kim S. Comparison of laxative effects of fermented soybeans ( Cheonggukjang ) containing toxins and biogenic amines against loperamide-induced constipation mouse model. Nutr Res Pract 2022;16:435. [DOI: 10.4162/nrp.2022.16.4.435] [Reference Citation Analysis]
29 Cong Z, Liang Y, Zhou Q, Darbalaei S, Zhao F, Feng W, Zhao L, Xu HE, Yang D, Wang M. Structural perspective of class B1 GPCR signaling. Trends in Pharmacological Sciences 2022. [DOI: 10.1016/j.tips.2022.01.002] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 3.0] [Reference Citation Analysis]
30 Murtaza B, Asghar F, Patoli D. GPR75: An exciting new target in metabolic syndrome and related disorders. Biochimie 2022. [DOI: 10.1016/j.biochi.2022.01.005] [Cited by in Crossref: 2] [Article Influence: 2.0] [Reference Citation Analysis]
31 Xu Z, Ikuta T, Kawakami K, Kise R, Qian Y, Xia R, Sun MX, Zhang A, Guo C, Cai XH, Huang Z, Inoue A, He Y. Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism. Nat Chem Biol 2021. [PMID: 34937912 DOI: 10.1038/s41589-021-00930-3] [Reference Citation Analysis]
32 Liu S, An J, Zhao J, Zhao S, Lv H, Wang S. Drug-Target Interaction Prediction Based on Multisource Information Weighted Fusion. Contrast Media Mol Imaging 2021;2021:6044256. [PMID: 34908912 DOI: 10.1155/2021/6044256] [Reference Citation Analysis]
33 Castleman P, Szwabowski G, Bowman D, Cole J, Parrill AL, Baker DL. Ligand-based G Protein Coupled Receptor pharmacophore modeling: Assessing the role of ligand function in model development. J Mol Graph Model 2021;111:108107. [PMID: 34915346 DOI: 10.1016/j.jmgm.2021.108107] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
34 Ringuet MT, Furness JB, Furness SGB. G protein-coupled receptor interactions and modification of signalling involving the ghrelin receptor, GHSR1a. J Neuroendocrinol 2021;:e13077. [PMID: 34931385 DOI: 10.1111/jne.13077] [Reference Citation Analysis]
35 Mitsumoto M, Sugaya K, Kazama K, Nakano R, Kosugi T, Murata T, Koga N. State-Targeting Stabilization of Adenosine A2A Receptor by Fusing a Custom-Made De Novo Designed α-Helical Protein. Int J Mol Sci 2021;22:12906. [PMID: 34884716 DOI: 10.3390/ijms222312906] [Reference Citation Analysis]
36 Woźniczka M, Błaszczak-Świątkiewicz K. New Generation of Meso and Antiprogestins (SPRMs) into the Osteoporosis Approach. Molecules 2021;26:6491. [PMID: 34770897 DOI: 10.3390/molecules26216491] [Reference Citation Analysis]
37 Bekker GJ, Araki M, Oshima K, Okuno Y, Kamiya N. Accurate Binding Configuration Prediction of a G-Protein-Coupled Receptor to Its Antagonist Using Multicanonical Molecular Dynamics-Based Dynamic Docking. J Chem Inf Model 2021;61:5161-71. [PMID: 34549581 DOI: 10.1021/acs.jcim.1c00712] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
38 Islam MA, Rallabandi VPS, Mohammed S, Srinivasan S, Natarajan S, Dudekula DB, Park J. Screening of β1- and β2-Adrenergic Receptor Modulators through Advanced Pharmacoinformatics and Machine Learning Approaches. Int J Mol Sci 2021;22:11191. [PMID: 34681845 DOI: 10.3390/ijms222011191] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
39 Atre I, Mizrahi N, Levavi-Sivan B. Characteristics of Neurokinin-3 Receptor and Its Binding Sites by Mutational Analysis. Biology (Basel) 2021;10:968. [PMID: 34681067 DOI: 10.3390/biology10100968] [Reference Citation Analysis]
40 Zhao F, Wu Y, Zhou F, Xue D, Zhao S, Lu W, Liu X, Hu T, Qiu Y, Li R, Gu T, Xu Y, Xu F, Zhong G, Jiang Z, Zhao S, Tao H. Elucidation of Distinct Modular Assemblies of Smoothened Receptor by Bitopic Ligand Measurement. J Med Chem 2021;64:13830-40. [PMID: 34492176 DOI: 10.1021/acs.jmedchem.1c01220] [Reference Citation Analysis]
41 Hwang DD, Lee SJ, Kim JH, Lee SM. The Role of Neuropeptides in Pathogenesis of Dry Dye. J Clin Med 2021;10:4248. [PMID: 34575359 DOI: 10.3390/jcm10184248] [Reference Citation Analysis]
42 Luyao H, Luesch H, Uy M. GPCR Pharmacological Profiling of Aaptamine from the Philippine Sponge Stylissa sp. Extends Its Therapeutic Potential for Noncommunicable Diseases. Molecules 2021;26:5618. [PMID: 34577088 DOI: 10.3390/molecules26185618] [Reference Citation Analysis]
43 Kong X, Li ZX, Gao YQ, Liu FH, Chen ZZ, Tian HG, Liu TX, Xu YY, Kang ZW. Genome-Wide Identification of Neuropeptides and Their Receptors in an Aphid Endoparasitoid Wasp, Aphidius gifuensi. Insects 2021;12:745. [PMID: 34442310 DOI: 10.3390/insects12080745] [Reference Citation Analysis]
44 Sarkar P, Chattopadhyay A. Cholesterol in GPCR Structures: Prevalence and Relevance. J Membr Biol 2021. [PMID: 34365520 DOI: 10.1007/s00232-021-00197-8] [Reference Citation Analysis]
45 Zhao F, Zhang C, Zhou Q, Hang K, Zou X, Chen Y, Wu F, Rao Q, Dai A, Yin W, Shen DD, Zhang Y, Xia T, Stevens RC, Xu HE, Yang D, Zhao L, Wang MW. Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor. Elife 2021;10:e68719. [PMID: 34254582 DOI: 10.7554/eLife.68719] [Cited by in Crossref: 2] [Article Influence: 2.0] [Reference Citation Analysis]
46 Cecchetti C, Strauss J, Stohrer C, Naylor C, Pryor E, Hobbs J, Tanley S, Goldman A, Byrne B. A novel high-throughput screen for identifying lipids that stabilise membrane proteins in detergent based solution. PLoS One 2021;16:e0254118. [PMID: 34252116 DOI: 10.1371/journal.pone.0254118] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
47 Wu Y, Zeng L, Zhao S. Ligands of Adrenergic Receptors: A Structural Point of View. Biomolecules 2021;11:936. [PMID: 34202543 DOI: 10.3390/biom11070936] [Reference Citation Analysis]
48 Machado JF, Correia JDG, Morais TS. Emerging Molecular Receptors for the Specific-Target Delivery of Ruthenium and Gold Complexes into Cancer Cells. Molecules 2021;26:3153. [PMID: 34070457 DOI: 10.3390/molecules26113153] [Reference Citation Analysis]
49 Liu N, Wang Y, Li T, Feng X. G-Protein Coupled Receptors (GPCRs): Signaling Pathways, Characterization, and Functions in Insect Physiology and Toxicology. Int J Mol Sci 2021;22:5260. [PMID: 34067660 DOI: 10.3390/ijms22105260] [Reference Citation Analysis]
50 Gonçalves-Monteiro S, Ribeiro-Oliveira R, Vieira-Rocha MS, Vojtek M, Sousa JB, Diniz C. Insights into Nuclear G-Protein-Coupled Receptors as Therapeutic Targets in Non-Communicable Diseases. Pharmaceuticals (Basel) 2021;14:439. [PMID: 34066915 DOI: 10.3390/ph14050439] [Reference Citation Analysis]
51 Infield DT, Rasouli A, Galles GD, Chipot C, Tajkhorshid E, Ahern CA. Cation-π Interactions and their Functional Roles in Membrane Proteins. J Mol Biol 2021;433:167035. [PMID: 33957146 DOI: 10.1016/j.jmb.2021.167035] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]