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For: Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Motivational activation: a unifying hypothesis of orexin/hypocretin function. Nat Neurosci 2014;17:1298-303. [PMID: 25254979 DOI: 10.1038/nn.3810] [Cited by in Crossref: 223] [Cited by in F6Publishing: 207] [Article Influence: 27.9] [Reference Citation Analysis]
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8 Alijanpour S, Khakpai F, Ebrahimi-ghiri M, Zarrindast M. Co-administration of the low dose of orexin and nitrergic antagonists induces an antidepressant-like effect in mice. Biomedicine & Pharmacotherapy 2019;109:589-94. [DOI: 10.1016/j.biopha.2018.10.033] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.7] [Reference Citation Analysis]
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10 Juvodden HT, Alnæs D, Lund MJ, Agartz I, Andreassen OA, Dietrichs E, Thorsby PM, Westlye LT, Knudsen S. Widespread white matter changes in post-H1N1 patients with narcolepsy type 1 and first-degree relatives. Sleep 2018;41. [DOI: 10.1093/sleep/zsy145] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 3.0] [Reference Citation Analysis]
11 Kuwaki T. Thermoregulation under pressure: a role for orexin neurons. Temperature (Austin) 2015;2:379-91. [PMID: 27227052 DOI: 10.1080/23328940.2015.1066921] [Cited by in Crossref: 22] [Cited by in F6Publishing: 16] [Article Influence: 3.1] [Reference Citation Analysis]
12 Duffet L, Kosar S, Panniello M, Viberti B, Bracey E, Zych AD, Radoux-Mergault A, Zhou X, Dernic J, Ravotto L, Tsai YC, Figueiredo M, Tyagarajan SK, Weber B, Stoeber M, Gogolla N, Schmidt MH, Adamantidis AR, Fellin T, Burdakov D, Patriarchi T. A genetically encoded sensor for in vivo imaging of orexin neuropeptides. Nat Methods 2022;19:231-41. [PMID: 35145320 DOI: 10.1038/s41592-021-01390-2] [Reference Citation Analysis]
13 De Groote A, de Kerchove d'Exaerde A. Thalamo-Nucleus Accumbens Projections in Motivated Behaviors and Addiction. Front Syst Neurosci 2021;15:711350. [PMID: 34335197 DOI: 10.3389/fnsys.2021.711350] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
14 Eban-Rothschild A, Giardino WJ, de Lecea L. To sleep or not to sleep: neuronal and ecological insights. Curr Opin Neurobiol 2017;44:132-8. [PMID: 28500869 DOI: 10.1016/j.conb.2017.04.010] [Cited by in Crossref: 42] [Cited by in F6Publishing: 28] [Article Influence: 8.4] [Reference Citation Analysis]
15 Levy KA, Brodnik ZD, Shaw JK, Perrey DA, Zhang Y, España RA. Hypocretin receptor 1 blockade produces bimodal modulation of cocaine-associated mesolimbic dopamine signaling. Psychopharmacology (Berl) 2017;234:2761-76. [PMID: 28667509 DOI: 10.1007/s00213-017-4673-y] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 3.6] [Reference Citation Analysis]
16 Faesel N, Kolodziejczyk MH, Koch M, Fendt M. Orexin deficiency affects sociability and the acquisition, expression, and extinction of conditioned social fear. Brain Res 2021;1751:147199. [PMID: 33160959 DOI: 10.1016/j.brainres.2020.147199] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
17 Kourosh-arami M, Gholami M, Alavi-kakhki SS, Komaki A. Neural correlates and potential targets for the contribution of orexin to addiction in cortical and subcortical areas. Neuropeptides 2022. [DOI: 10.1016/j.npep.2022.102259] [Reference Citation Analysis]
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20 Carvajal F, Alcaraz-iborra M, Lerma-cabrera JM, Valor LM, de la Fuente L, Sanchez-amate MDC, Cubero I. Orexin receptor 1 signaling contributes to ethanol binge-like drinking: Pharmacological and molecular evidence. Behavioural Brain Research 2015;287:230-7. [DOI: 10.1016/j.bbr.2015.03.046] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 2.0] [Reference Citation Analysis]
21 Cole S, Mayer HS, Petrovich GD. Orexin/Hypocretin-1 Receptor Antagonism Selectively Reduces Cue-Induced Feeding in Sated Rats and Recruits Medial Prefrontal Cortex and Thalamus. Sci Rep 2015;5:16143. [PMID: 26536818 DOI: 10.1038/srep16143] [Cited by in Crossref: 33] [Cited by in F6Publishing: 27] [Article Influence: 4.7] [Reference Citation Analysis]
22 Lopez MF, Moorman DE, Aston-Jones G, Becker HC. The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice. Brain Res 2016;1636:74-80. [PMID: 26851547 DOI: 10.1016/j.brainres.2016.01.049] [Cited by in Crossref: 42] [Cited by in F6Publishing: 35] [Article Influence: 7.0] [Reference Citation Analysis]
23 Wiskerke J, James MH, Aston-Jones G. The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task. Brain Res 2020;1731:146222. [PMID: 31002819 DOI: 10.1016/j.brainres.2019.04.017] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 3.3] [Reference Citation Analysis]
24 Wu G, Zhang X, Li S, Zhou D, Bai J, Wang H, Shu Q. Overexpression of ORX or MCH Protects Neurological Function Against Ischemic Stroke. Neurotox Res 2022. [PMID: 35013906 DOI: 10.1007/s12640-021-00457-4] [Reference Citation Analysis]
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27 Burdakov D. Reactive and predictive homeostasis: Roles of orexin/hypocretin neurons. Neuropharmacology 2019;154:61-7. [PMID: 30347195 DOI: 10.1016/j.neuropharm.2018.10.024] [Cited by in Crossref: 23] [Cited by in F6Publishing: 19] [Article Influence: 5.8] [Reference Citation Analysis]
28 Grafe LA, Bhatnagar S. The contribution of orexins to sex differences in the stress response. Brain Res 2020;1731:145893. [PMID: 30081036 DOI: 10.1016/j.brainres.2018.07.026] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 2.8] [Reference Citation Analysis]
29 Huang M, Chen C, Chen L, Chang H, Chen C, Lin S, Xu K. Chronic ketamine abuse is associated with orexin-A reduction and ACTH elevation. Psychopharmacology 2020;237:45-53. [DOI: 10.1007/s00213-019-05342-9] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 1.3] [Reference Citation Analysis]
30 Oldfield CS, Grossrubatscher I, Chávez M, Hoagland A, Huth AR, Carroll EC, Prendergast A, Qu T, Gallant JL, Wyart C, Isacoff EY. Experience, circuit dynamics, and forebrain recruitment in larval zebrafish prey capture. Elife 2020;9:e56619. [PMID: 32985972 DOI: 10.7554/eLife.56619] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
31 Filardi M, Pizza F, Bruni O, Natale V, Plazzi G. Circadian Rest-Activity Rhythm in Pediatric Type 1 Narcolepsy. Sleep 2016;39:1241-7. [PMID: 27091539 DOI: 10.5665/sleep.5842] [Cited by in Crossref: 19] [Cited by in F6Publishing: 14] [Article Influence: 3.2] [Reference Citation Analysis]
32 Mohammadkhani A, Fragale JE, Pantazis CB, Bowrey HE, James MH, Aston-Jones G. Orexin-1 Receptor Signaling in Ventral Pallidum Regulates Motivation for the Opioid Remifentanil. J Neurosci 2019;39:9831-40. [PMID: 31641055 DOI: 10.1523/JNEUROSCI.0255-19.2019] [Cited by in Crossref: 16] [Cited by in F6Publishing: 8] [Article Influence: 5.3] [Reference Citation Analysis]
33 Xiang J, Zhang S, Xu R, Chu H, Biswas S, Yu S, Miao D, Li W, Li S, Brown AJ, Yang H, Xu Y, Li B, Liu H. Elevated HB-EGF expression in neural stem cells causes middle age obesity by suppressing Hypocretin/Orexin expression. FASEB J 2021;35:e21345. [PMID: 33715219 DOI: 10.1096/fj.202001945R] [Reference Citation Analysis]
34 Freeman LR, Aston-Jones G. Activation of medial hypothalamic orexin neurons during a Go/No-Go task. Brain Res 2020;1731:145928. [PMID: 30176242 DOI: 10.1016/j.brainres.2018.08.031] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
35 Kukushkin ML, Poluektov MG. Current Views on Chronic Pain and Its Relationship to the State of Sleep. Neurosci Behav Physi 2019;49:13-9. [DOI: 10.1007/s11055-018-0684-3] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
36 Korim WS, Llewellyn-Smith IJ, Verberne AJ. Activation of Medulla-Projecting Perifornical Neurons Modulates the Adrenal Sympathetic Response to Hypoglycemia: Involvement of Orexin Type 2 (OX2-R) Receptors. Endocrinology 2016;157:810-9. [PMID: 26653571 DOI: 10.1210/en.2015-1712] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 3.1] [Reference Citation Analysis]
37 Muehlan C, Heuberger J, Juif P, Croft M, van Gerven J, Dingemanse J. Accelerated Development of the Dual Orexin Receptor Antagonist ACT-541468: Integration of a Microtracer in a First-in-Human Study. Clin Pharmacol Ther 2018;104:1022-9. [DOI: 10.1002/cpt.1046] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 6.0] [Reference Citation Analysis]
38 Miyata K, Kuwaki T, Ootsuka Y. The integrated ultradian organization of behavior and physiology in mice and the contribution of orexin to the ultradian patterning. Neuroscience 2016;334:119-33. [PMID: 27491480 DOI: 10.1016/j.neuroscience.2016.07.041] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 2.0] [Reference Citation Analysis]
39 Tashiro S, Yamaguchi R, Ishikawa S, Sakurai T, Kajiya K, Kanmura Y, Kuwaki T, Kashiwadani H. Odour-induced analgesia mediated by hypothalamic orexin neurons in mice. Sci Rep 2016;6:37129. [PMID: 27845440 DOI: 10.1038/srep37129] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 3.2] [Reference Citation Analysis]
40 Farrell MR, Schoch H, Mahler SV. Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms. Prog Neuropsychopharmacol Biol Psychiatry 2018;87:33-47. [PMID: 29305936 DOI: 10.1016/j.pnpbp.2018.01.002] [Cited by in Crossref: 39] [Cited by in F6Publishing: 31] [Article Influence: 9.8] [Reference Citation Analysis]
41 James MH, Campbell EJ, Dayas CV. Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders. Curr Top Behav Neurosci 2017;33:197-219. [PMID: 28083790 DOI: 10.1007/7854_2016_56] [Cited by in Crossref: 55] [Cited by in F6Publishing: 55] [Article Influence: 11.0] [Reference Citation Analysis]
42 Muehlan C, Vaillant C, Zenklusen I, Kraehenbuehl S, Dingemanse J. Clinical pharmacology, efficacy, and safety of orexin receptor antagonists for the treatment of insomnia disorders. Expert Opinion on Drug Metabolism & Toxicology 2020;16:1063-78. [DOI: 10.1080/17425255.2020.1817380] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 6.5] [Reference Citation Analysis]
43 Castro DC, Berridge KC. Opioid and orexin hedonic hotspots in rat orbitofrontal cortex and insula. Proc Natl Acad Sci U S A 2017;114:E9125-34. [PMID: 29073109 DOI: 10.1073/pnas.1705753114] [Cited by in Crossref: 62] [Cited by in F6Publishing: 52] [Article Influence: 12.4] [Reference Citation Analysis]
44 Naef L, Pitman KA, Borgland SL. Mesolimbic dopamine and its neuromodulators in obesity and binge eating. CNS Spectr 2015;20:574-83. [PMID: 26514168 DOI: 10.1017/S1092852915000693] [Cited by in Crossref: 34] [Cited by in F6Publishing: 20] [Article Influence: 4.9] [Reference Citation Analysis]
45 Karimi S, Hamidi G, Fatahi Z, Haghparast A. Orexin 1 receptors in the anterior cingulate and orbitofrontal cortex regulate cost and benefit decision-making. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2019;89:227-35. [DOI: 10.1016/j.pnpbp.2018.09.006] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.7] [Reference Citation Analysis]
46 Khani A, Rainer G. Neural and neurochemical basis of reinforcement-guided decision making. J Neurophysiol 2016;116:724-41. [PMID: 27226454 DOI: 10.1152/jn.01113.2015] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 2.2] [Reference Citation Analysis]
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50 Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. Addict Biol 2020;25:e12795. [PMID: 31297913 DOI: 10.1111/adb.12795] [Cited by in Crossref: 21] [Cited by in F6Publishing: 20] [Article Influence: 10.5] [Reference Citation Analysis]
51 Alcaraz-iborra M, Cubero I. Do Orexins contribute to impulsivity-driven binge consumption of rewarding stimulus and transition to drug/food dependence? Pharmacology Biochemistry and Behavior 2015;134:31-4. [DOI: 10.1016/j.pbb.2015.04.012] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
52 Kirouac GJ. Placing the paraventricular nucleus of the thalamus within the brain circuits that control behavior. Neuroscience & Biobehavioral Reviews 2015;56:315-29. [DOI: 10.1016/j.neubiorev.2015.08.005] [Cited by in Crossref: 156] [Cited by in F6Publishing: 151] [Article Influence: 22.3] [Reference Citation Analysis]
53 He S, Brooks AT, Kampman KM, Chakravorty S. The Relationship between Alcohol Craving and Insomnia Symptoms in Alcohol-Dependent Individuals. Alcohol Alcohol 2019;54:287-94. [PMID: 31087085 DOI: 10.1093/alcalc/agz029] [Cited by in Crossref: 11] [Cited by in F6Publishing: 7] [Article Influence: 3.7] [Reference Citation Analysis]
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55 Feillet CA, Bainier C, Mateo M, Blancas-Velázquez A, Salaberry NL, Ripperger JA, Albrecht U, Mendoza J. Rev-erbα modulates the hypothalamic orexinergic system to influence pleasurable feeding behaviour in mice. Addict Biol 2017;22:411-22. [PMID: 26632340 DOI: 10.1111/adb.12339] [Cited by in Crossref: 25] [Cited by in F6Publishing: 25] [Article Influence: 5.0] [Reference Citation Analysis]
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57 Radke AK, Sneddon EA, Frasier RM, Hopf FW. Recent Perspectives on Sex Differences in Compulsion-Like and Binge Alcohol Drinking. Int J Mol Sci 2021;22:3788. [PMID: 33917517 DOI: 10.3390/ijms22073788] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
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63 Schmeichel BE, Matzeu A, Koebel P, Vendruscolo LF, Sidhu H, Shahryari R, Kieffer BL, Koob GF, Martin-Fardon R, Contet C. Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats. Neuropsychopharmacology 2018;43:2373-82. [PMID: 29703996 DOI: 10.1038/s41386-018-0054-4] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 5.0] [Reference Citation Analysis]
64 Risco S, Mediavilla C. Orexin A in the ventral tegmental area enhances saccharin-induced conditioned flavor preference: The role of D1 receptors in central nucleus of amygdala. Behavioural Brain Research 2018;348:192-200. [DOI: 10.1016/j.bbr.2018.04.010] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
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