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For: Perrey DA, Gilmour BP, Thomas BF, Zhang Y. Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers. ACS Med Chem Lett 2014;5:634-8. [PMID: 24944734 DOI: 10.1021/ml4004759] [Cited by in Crossref: 22] [Cited by in F6Publishing: 18] [Article Influence: 2.8] [Reference Citation Analysis]
Number Citing Articles
1 Perrey DA, Decker AM, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor. Bioorg Med Chem 2015;23:5709-24. [PMID: 26216017 DOI: 10.1016/j.bmc.2015.07.013] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 1.9] [Reference Citation Analysis]
2 Perrey DA, German NA, Decker AM, Thorn D, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor. ACS Chem Neurosci 2015;6:599-614. [PMID: 25643283 DOI: 10.1021/cn500330v] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 1.6] [Reference Citation Analysis]
3 Ligresti A, De Petrocellis L, Di Marzo V. From Phytocannabinoids to Cannabinoid Receptors and Endocannabinoids: Pleiotropic Physiological and Pathological Roles Through Complex Pharmacology. Physiological Reviews 2016;96:1593-659. [DOI: 10.1152/physrev.00002.2016] [Cited by in Crossref: 184] [Cited by in F6Publishing: 175] [Article Influence: 30.7] [Reference Citation Analysis]
4 Freitas HR, Isaac AR, Silva TM, Diniz GOF, dos Santos Dabdab Y, Bockmann EC, Guimarães MZP, da Costa Calaza K, de Mello FG, Ventura ALM, de Melo Reis RA, França GR. Cannabinoids Induce Cell Death and Promote P2X7 Receptor Signaling in Retinal Glial Progenitors in Culture. Mol Neurobiol 2019;56:6472-86. [DOI: 10.1007/s12035-019-1537-y] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
5 Botta J, Appelhans J, Mccormick PJ. Continuing challenges in targeting oligomeric GPCR-based drugs. Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors. Elsevier; 2020. pp. 213-45. [DOI: 10.1016/bs.pmbts.2019.11.009] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
6 Perrey DA, Decker AM, Zhang Y. Synthesis and Evaluation of Orexin-1 Receptor Antagonists with Improved Solubility and CNS Permeability. ACS Chem Neurosci 2018;9:587-602. [PMID: 29129052 DOI: 10.1021/acschemneuro.7b00402] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.8] [Reference Citation Analysis]
7 Newman AH, Battiti FO, Bonifazi A. 2016 Philip S. Portoghese Medicinal Chemistry Lectureship: Designing Bivalent or Bitopic Molecules for G-Protein Coupled Receptors. The Whole Is Greater Than the Sum of Its Parts. J Med Chem 2020;63:1779-97. [PMID: 31499001 DOI: 10.1021/acs.jmedchem.9b01105] [Cited by in Crossref: 25] [Cited by in F6Publishing: 23] [Article Influence: 8.3] [Reference Citation Analysis]
8 Colín-González AL, Aguilera G, Santamaría A. Cannabinoids: Glutamatergic Transmission and Kynurenines. Adv Neurobiol 2016;12:173-98. [PMID: 27651254 DOI: 10.1007/978-3-319-28383-8_10] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 2.0] [Reference Citation Analysis]
9 Busquets-Garcia A, Bains J, Marsicano G. CB1 Receptor Signaling in the Brain: Extracting Specificity from Ubiquity. Neuropsychopharmacology 2018;43:4-20. [PMID: 28862250 DOI: 10.1038/npp.2017.206] [Cited by in Crossref: 109] [Cited by in F6Publishing: 99] [Article Influence: 21.8] [Reference Citation Analysis]
10 Aghazadeh Tabrizi M, Baraldi PG, Borea PA, Varani K. Medicinal Chemistry, Pharmacology, and Potential Therapeutic Benefits of Cannabinoid CB2 Receptor Agonists. Chem Rev 2016;116:519-60. [PMID: 26741146 DOI: 10.1021/acs.chemrev.5b00411] [Cited by in Crossref: 61] [Cited by in F6Publishing: 58] [Article Influence: 10.2] [Reference Citation Analysis]
11 Chanphai P, Agudelo D, Vesper AR, Bérubé G, Tajmir-Riahi HA. Testosterone and its dimers alter tRNA morphology. J Pharm Biomed Anal 2017;134:269-74. [PMID: 27930994 DOI: 10.1016/j.jpba.2016.11.053] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 1.2] [Reference Citation Analysis]
12 Nimczick M, Decker M. New Approaches in the Design and Development of Cannabinoid Receptor Ligands: Multifunctional and Bivalent Compounds. ChemMedChem 2015;10:773-86. [DOI: 10.1002/cmdc.201500041] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 3.3] [Reference Citation Analysis]
13 Perrey DA, Zhang Y. Therapeutics development for addiction: Orexin-1 receptor antagonists. Brain Res 2020;1731:145922. [PMID: 30148984 DOI: 10.1016/j.brainres.2018.08.025] [Cited by in Crossref: 22] [Cited by in F6Publishing: 23] [Article Influence: 5.5] [Reference Citation Analysis]
14 Grant PS, Kahlcke N, Govindpani K, Hunter M, MacDonald C, Brimble MA, Glass M, Furkert DP. Divalent cannabinoid-1 receptor ligands: A linker attachment point survey of SR141716A for development of high-affinity CB1R molecular probes. Bioorg Med Chem Lett 2019;29:126644. [PMID: 31564385 DOI: 10.1016/j.bmcl.2019.126644] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
15 Zou S, Kumar U. Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. Int J Mol Sci 2018;19:E833. [PMID: 29533978 DOI: 10.3390/ijms19030833] [Cited by in Crossref: 234] [Cited by in F6Publishing: 217] [Article Influence: 58.5] [Reference Citation Analysis]
16 Haspula D, Clark MA. Cannabinoid Receptors: An Update on Cell Signaling, Pathophysiological Roles and Therapeutic Opportunities in Neurological, Cardiovascular, and Inflammatory Diseases. Int J Mol Sci 2020;21:E7693. [PMID: 33080916 DOI: 10.3390/ijms21207693] [Cited by in Crossref: 23] [Cited by in F6Publishing: 21] [Article Influence: 11.5] [Reference Citation Analysis]
17 Glass M, Govindpani K, Furkert DP, Hurst DP, Reggio PH, Flanagan JU. One for the Price of Two…Are Bivalent Ligands Targeting Cannabinoid Receptor Dimers Capable of Simultaneously Binding to both Receptors? Trends Pharmacol Sci 2016;37:353-63. [PMID: 26917061 DOI: 10.1016/j.tips.2016.01.010] [Cited by in Crossref: 18] [Cited by in F6Publishing: 21] [Article Influence: 3.0] [Reference Citation Analysis]
18 Berrendero F, Flores Á, Robledo P. When orexins meet cannabinoids: Bidirectional functional interactions. Biochemical Pharmacology 2018;157:43-50. [DOI: 10.1016/j.bcp.2018.08.040] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
19 Morales P, Reggio PH. An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors. Cannabis Cannabinoid Res 2017;2:265-73. [PMID: 29098189 DOI: 10.1089/can.2017.0036] [Cited by in Crossref: 74] [Cited by in F6Publishing: 66] [Article Influence: 14.8] [Reference Citation Analysis]
20 Dolles D, Hoffmann M, Gunesch S, Marinelli O, Möller J, Santoni G, Chatonnet A, Lohse MJ, Wittmann HJ, Strasser A, Nabissi M, Maurice T, Decker M. Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles. J Med Chem 2018;61:1646-63. [PMID: 29400965 DOI: 10.1021/acs.jmedchem.7b01760] [Cited by in Crossref: 32] [Cited by in F6Publishing: 31] [Article Influence: 8.0] [Reference Citation Analysis]