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Mota BC, Ashburner N, Abelleira-hervas L, Liu L, Aleksynas R, Rovati LC, Caselli G, Sastre M. I2-Imidazoline Ligand CR4056 Improves Memory, Increases ApoE Expression and Reduces BBB Leakage in 5xFAD Mice. IJMS 2022;23:7320. [DOI: 10.3390/ijms23137320] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
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Nadal Rodríguez P, Ghashghaei O, Bagán A, Escolano C, Lavilla R. Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design. Biomedicines 2022;10:1488. [DOI: 10.3390/biomedicines10071488] [Reference Citation Analysis]
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Bagán A, Morales-García JA, Griñán-Ferré C, Díaz C, Pérez Del Palacio J, Ramos MC, Vicente F, Pérez B, Brea J, Loza MI, Pallàs M, Escolano C. Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I2 Receptor Ligand B06. Int J Mol Sci 2022;23:5408. [PMID: 35628219 DOI: 10.3390/ijms23105408] [Reference Citation Analysis]
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Jiménez-altayó F, Cabrera A, Bagán A, Giménez-llort L, D’ocon P, Pérez B, Pallàs M, Escolano C. An Imidazoline 2 Receptor Ligand Relaxes Mouse Aorta via Off-Target Mechanisms Resistant to Aging. Front Pharmacol 2022;13:826837. [DOI: 10.3389/fphar.2022.826837] [Reference Citation Analysis]
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Vasilopoulou F, Escolano C, Pallàs M, Griñán-Ferré C. Microarray Analysis Revealed Inflammatory Transcriptomic Changes after LSL60101 Treatment in 5XFAD Mice Model. Genes (Basel) 2021;12:1315. [PMID: 34573297 DOI: 10.3390/genes12091315] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
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Vasilopoulou F, Rodríguez-Arévalo S, Bagán A, Escolano C, Griñán-Ferré C, Pallàs M. Disease-modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: a comparative study with donepezil. Br J Pharmacol 2021;178:3017-33. [PMID: 33817786 DOI: 10.1111/bph.15478] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 4.5] [Reference Citation Analysis]
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Rodriguez-Arévalo S, Bagán A, Griñán-Ferré C, Vasilopoulou F, Pallàs M, Brocos-Mosquera I, Callado LF, Loza MI, Martínez AL, Brea J, Pérez B, Molins E, De Jonghe S, Daelemans D, Radan M, Djikic T, Nikolic K, Hernández-Hernández E, García-Fuster MJ, García-Sevilla JA, Escolano C. Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer's disease. Eur J Med Chem 2021;222:113540. [PMID: 34118720 DOI: 10.1016/j.ejmech.2021.113540] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
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Hernández-hernández E, García-fuster MJ. Evaluating the effects of 2-BFI and tracizoline, two potent I2-imidazoline receptor agonists, on cognitive performance and affect in middle-aged rats. Naunyn-Schmiedeberg's Arch Pharmacol 2021;394:989-96. [DOI: 10.1007/s00210-020-02042-6] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
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Vasilopoulou F, Griñán-Ferré C, Rodríguez-Arévalo S, Bagán A, Abás S, Escolano C, Pallàs M. I2 imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway. Geroscience 2021;43:965-83. [PMID: 33128688 DOI: 10.1007/s11357-020-00281-2] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
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Kotagale N, Dixit M, Garmelwar H, Bhondekar S, Umekar M, Taksande B. Agmatine reverses memory deficits induced by Aβ1–42 peptide in mice: A key role of imidazoline receptors. Pharmacology Biochemistry and Behavior 2020;196:172976. [DOI: 10.1016/j.pbb.2020.172976] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 1.3] [Reference Citation Analysis]
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Hernández-hernández E, García-sevilla JA, García-fuster MJ. Exploring the antidepressant-like potential of the selective I2-imidazoline receptor ligand LSL 60101 in adult male rats. Pharmacol Rep 2021;73:288-95. [DOI: 10.1007/s43440-020-00148-5] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
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Vasilopoulou F, Bagan A, Rodriguez-Arevalo S, Escolano C, Griñán-Ferré C, Pallàs M. Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I2-Imidazoline Receptor Ligand MCR5. Pharmaceutics 2020;12:E475. [PMID: 32456135 DOI: 10.3390/pharmaceutics12050475] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
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