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For: Checler F, Afram E, Pardossi-Piquard R, Lauritzen I. Is γ-secretase a beneficial inactivating enzyme of the toxic APP C-terminal fragment C99? J Biol Chem 2021;296:100489. [PMID: 33662398 DOI: 10.1016/j.jbc.2021.100489] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 8.5] [Reference Citation Analysis]
Number Citing Articles
1 Klein M, Hermey G. Converging links between adult-onset neurodegenerative Alzheimer's disease and early life neurodegenerative neuronal ceroid lipofuscinosis? Neural Regen Res 2023;18:1463-71. [PMID: 36571343 DOI: 10.4103/1673-5374.361544] [Reference Citation Analysis]
2 Svedružić ŽM, Šendula Jengić V, Ostojić L. The Binding of Different Substrate Molecules at the Docking Site and the Active Site of γ-Secretase Can Trigger Toxic Events in Sporadic and Familial Alzheimer’s Disease. IJMS 2023;24:1835. [DOI: 10.3390/ijms24031835] [Reference Citation Analysis]
3 Mary A, Eysert F, Checler F, Chami M. Mitophagy in Alzheimer's disease: Molecular defects and therapeutic approaches. Mol Psychiatry 2023;28:202-16. [PMID: 35665766 DOI: 10.1038/s41380-022-01631-6] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 6.0] [Reference Citation Analysis]
4 Pan AL, Audrain M, Sakakibara E, Joshi R, Zhu X, Wang Q, Wang M, Beckmann ND, Schadt EE, Gandy S, Zhang B, Ehrlich ME, Salton SR. Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females. Cells 2022;11. [PMID: 36497141 DOI: 10.3390/cells11233880] [Reference Citation Analysis]
5 Jordà-Siquier T, Petrel M, Kouskoff V, Smailovic U, Cordelières F, Frykman S, Müller U, Mulle C, Barthet G. APP accumulates with presynaptic proteins around amyloid plaques: A role for presynaptic mechanisms in Alzheimer's disease? Alzheimers Dement 2022;18:2099-116. [PMID: 35076178 DOI: 10.1002/alz.12546] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 8.0] [Reference Citation Analysis]
6 Petit D, Hitzenberger M, Koch M, Lismont S, Zoltowska KM, Enzlein T, Hopf C, Zacharias M, Chávez-Gutiérrez L. Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP. EMBO J 2022;:e111084. [PMID: 36121025 DOI: 10.15252/embj.2022111084] [Reference Citation Analysis]
7 Im E, Jiang Y, Stavrides P, Darji S, Erdjument-bromage H, Neubert TA, Bordi M, Choi JY, Lee J, Nixon RA. Lysosomal dysfunction in Down Syndrome and Alzheimer mouse models is caused by selective v-ATPase inhibition by Tyr682 phosphorylated APP βCTF.. [DOI: 10.1101/2022.06.02.494546] [Reference Citation Analysis]
8 Yang S, Du Y, Zhao X, Wu C, Yu P. Reducing PDK1/Akt Activity: An Effective Therapeutic Target in the Treatment of Alzheimer's Disease. Cells 2022;11:1735. [PMID: 35681431 DOI: 10.3390/cells11111735] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
9 Kasu YAT, Arva A, Johnson J, Sajan C, Manzano J, Hennes A, Haynes J, Brower CS. BAG6 prevents the aggregation of neurodegeneration-associated fragments of TDP43. iScience 2022;25:104273. [DOI: 10.1016/j.isci.2022.104273] [Reference Citation Analysis]
10 Svedružić ŽM, Jengić VŠ, Ostojić L. Binding of different substrate molecules at the docking site and the active site of γ-secretase can trigger toxic events in sporadic and familial Alzheimer’s disease.. [DOI: 10.1101/2022.04.12.487996] [Reference Citation Analysis]
11 Sandberg AA, Manning E, Wilkins HM, Mazzarino R, Minckley T, Swerdlow RH, Patterson D, Qin Y, Linseman DA. Mitochondrial Targeting of Amyloid-β Protein Precursor Intracellular Domain Induces Hippocampal Cell Death via a Mechanism Distinct from Amyloid-β. JAD 2022. [DOI: 10.3233/jad-215108] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
12 Wen J, Liu D, Zhao L. Small molecules targeting γ-secretase and their potential biological applications. European Journal of Medicinal Chemistry 2022. [DOI: 10.1016/j.ejmech.2022.114169] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
13 Velasco-bolom J, Domínguez L. Mechanistic regulation of γ-secretase by their substrates. Phys Chem Chem Phys . [DOI: 10.1039/d2cp01714h] [Reference Citation Analysis]
14 Yang S, Magnutzki A, Alami NO, Lattke M, Hein TM, Scheller JS, Kröger C, Oswald F, Yilmazer-Hanke D, Wirth T, Baumann B. IKK2/NF-κB Activation in Astrocytes Reduces amyloid β Deposition: A Process Associated with Specific Microglia Polarization. Cells 2021;10:2669. [PMID: 34685649 DOI: 10.3390/cells10102669] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
15 Chen XQ, Xing Z, Chen QD, Salvi RJ, Zhang X, Tycko B, Mobley WC, Yu YE. Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome. Front Aging Neurosci 2021;13:700280. [PMID: 34276349 DOI: 10.3389/fnagi.2021.700280] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]