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For: Withers-Martinez C, Suarez C, Fulle S, Kher S, Penzo M, Ebejer JP, Koussis K, Hackett F, Jirgensons A, Finn P, Blackman MJ. Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target. Int J Parasitol 2012;42:597-612. [PMID: 22543039 DOI: 10.1016/j.ijpara.2012.04.005] [Cited by in Crossref: 37] [Cited by in F6Publishing: 38] [Article Influence: 3.7] [Reference Citation Analysis]
Number Citing Articles
1 Lidumniece E, Withers-Martinez C, Hackett F, Blackman MJ, Jirgensons A. Subtilisin-like Serine Protease 1 (SUB1) as an Emerging Antimalarial Drug Target: Current Achievements in Inhibitor Discovery. J Med Chem 2022. [PMID: 36137276 DOI: 10.1021/acs.jmedchem.2c01093] [Reference Citation Analysis]
2 Putaporntip C, Kuamsab N, Rojrung R, Seethamchai S, Jongwutiwes S. Structural organization and sequence diversity of the complete nucleotide sequence encoding the Plasmodium malariae merozoite surface protein-1. Sci Rep 2022;12. [DOI: 10.1038/s41598-022-19049-z] [Reference Citation Analysis]
3 Gomes PS, Carneiro MPD, Machado PDA, de Andrade-neto VV, da Fonseca-martins AM, Goundry A, Pereira da Silva JVM, Gomes DCO, Lima APCDA, Ennes-vidal V, Sodero ACR, De-simone SG, de Matos Guedes HL. Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor. CIMB 2022;44:2089-106. [DOI: 10.3390/cimb44050141] [Reference Citation Analysis]
4 Bahl V, Chaddha K, Mian SY, Holder AA, Knuepfer E, Gaur D. Genetic disruption of Plasmodium falciparum Merozoite surface antigen 180 (PfMSA180) suggests an essential role during parasite egress from erythrocytes. Sci Rep 2021;11:19183. [PMID: 34584166 DOI: 10.1038/s41598-021-98707-0] [Reference Citation Analysis]
5 Rout UK, Sanket AS, Sisodia BS, Mohapatra PK, Pati S, Kant R, Dwivedi GR. A Comparative Review on Current and Future Drug Targets Against Bacteria & Malaria. Curr Drug Targets 2020;21:736-75. [PMID: 31995004 DOI: 10.2174/1389450121666200129103618] [Reference Citation Analysis]
6 Sojka D, Šnebergerová P, Robbertse L. Protease Inhibition-An Established Strategy to Combat Infectious Diseases. Int J Mol Sci 2021;22:5762. [PMID: 34071206 DOI: 10.3390/ijms22115762] [Cited by in F6Publishing: 3] [Reference Citation Analysis]
7 Tan MSY, Koussis K, Withers-Martinez C, Howell SA, Thomas JA, Hackett F, Knuepfer E, Shen M, Hall MD, Snijders AP, Blackman MJ. Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor. EMBO J 2021;40:e107226. [PMID: 33932049 DOI: 10.15252/embj.2020107226] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
8 Ojha PK, Kumar V, Roy J, Roy K. Recent advances in quantitative structure-activity relationship models of antimalarial drugs. Expert Opin Drug Discov 2021;16:659-95. [PMID: 33356651 DOI: 10.1080/17460441.2021.1866535] [Cited by in Crossref: 2] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
9 Tarr SJ, Withers-Martinez C, Flynn HR, Snijders AP, Masino L, Koussis K, Conway DJ, Blackman MJ. A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1. Biochem J 2020;477:525-40. [PMID: 31942933 DOI: 10.1042/BCJ20190918] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
10 Tan QW, Mutwil M. Malaria.tools-comparative genomic and transcriptomic database for Plasmodium species. Nucleic Acids Res 2020;48:D768-75. [PMID: 31372645 DOI: 10.1093/nar/gkz662] [Cited by in Crossref: 5] [Cited by in F6Publishing: 7] [Article Influence: 2.5] [Reference Citation Analysis]
11 Burns AL, Dans MG, Balbin JM, de Koning-Ward TF, Gilson PR, Beeson JG, Boyle MJ, Wilson DW. Targeting malaria parasite invasion of red blood cells as an antimalarial strategy. FEMS Microbiol Rev 2019;43:223-38. [PMID: 30753425 DOI: 10.1093/femsre/fuz005] [Cited by in Crossref: 28] [Cited by in F6Publishing: 28] [Article Influence: 9.3] [Reference Citation Analysis]
12 Mishra M, Singh V, Singh S. Structural Insights Into Key Plasmodium Proteases as Therapeutic Drug Targets. Front Microbiol 2019;10:394. [PMID: 30891019 DOI: 10.3389/fmicb.2019.00394] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 3.7] [Reference Citation Analysis]
13 Pino P, Caldelari R, Mukherjee B, Vahokoski J, Klages N, Maco B, Collins CR, Blackman MJ, Kursula I, Heussler V, Brochet M, Soldati-Favre D. A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress. Science 2017;358:522-8. [PMID: 29074775 DOI: 10.1126/science.aaf8675] [Cited by in Crossref: 61] [Cited by in F6Publishing: 63] [Article Influence: 15.3] [Reference Citation Analysis]
14 Ukegbu CV, Akinosoglou KA, Christophides GK, Vlachou D. Plasmodium berghei PIMMS2 Promotes Ookinete Invasion of the Anopheles gambiae Mosquito Midgut. Infect Immun 2017;85:e00139-17. [PMID: 28559405 DOI: 10.1128/IAI.00139-17] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 1.8] [Reference Citation Analysis]
15 Babar PH, Dey V, Jaiswar P, Patankar S. An insertion in the methyltransferase domain of P. falciparum trimethylguanosine synthase harbors a classical nuclear localization signal. Mol Biochem Parasitol 2016;210:58-70. [PMID: 27619053 DOI: 10.1016/j.molbiopara.2016.08.007] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
16 Das S, Hertrich N, Perrin AJ, Withers-Martinez C, Collins CR, Jones ML, Watermeyer JM, Fobes ET, Martin SR, Saibil HR, Wright GJ, Treeck M, Epp C, Blackman MJ. Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs. Cell Host Microbe 2015;18:433-44. [PMID: 26468747 DOI: 10.1016/j.chom.2015.09.007] [Cited by in Crossref: 102] [Cited by in F6Publishing: 91] [Article Influence: 17.0] [Reference Citation Analysis]
17 Beeson JG, Drew DR, Boyle MJ, Feng G, Fowkes FJ, Richards JS. Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria. FEMS Microbiol Rev 2016;40:343-72. [PMID: 26833236 DOI: 10.1093/femsre/fuw001] [Cited by in Crossref: 177] [Cited by in F6Publishing: 175] [Article Influence: 29.5] [Reference Citation Analysis]
18 Brogi S, Giovani S, Brindisi M, Gemma S, Novellino E, Campiani G, Blackman MJ, Butini S. In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors. J Mol Graph Model 2016;64:121-30. [PMID: 26826801 DOI: 10.1016/j.jmgm.2016.01.005] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 2.5] [Reference Citation Analysis]
19 Aneja B, Kumar B, Jairajpuri MA, Abid M. A structure guided drug-discovery approach towards identification of Plasmodium inhibitors. RSC Adv 2016;6:18364-406. [DOI: 10.1039/c5ra19673f] [Cited by in Crossref: 17] [Cited by in F6Publishing: 13] [Article Influence: 2.8] [Reference Citation Analysis]
20 Stallmach R, Kavishwar M, Withers-Martinez C, Hackett F, Collins CR, Howell SA, Yeoh S, Knuepfer E, Atid AJ, Holder AA, Blackman MJ. Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle. Mol Microbiol 2015;96:368-87. [PMID: 25599609 DOI: 10.1111/mmi.12941] [Cited by in Crossref: 40] [Cited by in F6Publishing: 36] [Article Influence: 5.7] [Reference Citation Analysis]
21 Giovani S, Penzo M, Butini S, Brindisi M, Gemma S, Novellino E, Campiani G, Blackman MJ, Brogi S. Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors. RSC Adv 2015;5:22431-48. [DOI: 10.1039/c5ra01170a] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 1.9] [Reference Citation Analysis]
22 Kher SS, Penzo M, Fulle S, Ebejer JP, Finn PW, Blackman MJ, Jirgensons A. Quinoxaline-Based Inhibitors of Malarial Protease PfSUB1*. Chem Heterocycl Comp 2015;50:1457-63. [DOI: 10.1007/s10593-014-1610-4] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
23 Kher SS, Penzo M, Fulle S, Finn PW, Blackman MJ, Jirgensons A. Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1. Bioorg Med Chem Lett 2014;24:4486-9. [PMID: 25129616 DOI: 10.1016/j.bmcl.2014.07.086] [Cited by in Crossref: 13] [Cited by in F6Publishing: 16] [Article Influence: 1.6] [Reference Citation Analysis]
24 Drinkwater N, Mcgowan S. From crystal to compound: structure-based antimalarial drug discovery. Biochemical Journal 2014;461:349-69. [DOI: 10.1042/bj20140240] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
25 Nethavhani SA, van Ree T. Synthesis and Antimalarial Activities of Some Novel 2-Pyridones. Arab J Sci Eng 2014;39:6595-8. [DOI: 10.1007/s13369-014-1193-5] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
26 Giovani S, Penzo M, Brogi S, Brindisi M, Gemma S, Novellino E, Savini L, Blackman MJ, Campiani G, Butini S. Rational design of the first difluorostatone-based PfSUB1 inhibitors. Bioorg Med Chem Lett 2014;24:3582-6. [PMID: 24909083 DOI: 10.1016/j.bmcl.2014.05.044] [Cited by in Crossref: 29] [Cited by in F6Publishing: 33] [Article Influence: 3.6] [Reference Citation Analysis]
27 Withers-Martinez C, Strath M, Hackett F, Haire LF, Howell SA, Walker PA, Christodoulou E, Dodson GG, Blackman MJ. The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin. Nat Commun 2014;5:3726. [PMID: 24785947 DOI: 10.1038/ncomms4726] [Cited by in Crossref: 31] [Cited by in F6Publishing: 31] [Article Influence: 3.9] [Reference Citation Analysis]
28 Karthik L, Kumar G, Keswani T, Bhattacharyya A, Chandar SS, Bhaskara Rao KV. Protease inhibitors from marine actinobacteria as a potential source for antimalarial compound. PLoS One 2014;9:e90972. [PMID: 24618707 DOI: 10.1371/journal.pone.0090972] [Cited by in Crossref: 57] [Cited by in F6Publishing: 80] [Article Influence: 7.1] [Reference Citation Analysis]
29 Alam A. Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets. Interdiscip Perspect Infect Dis 2014;2014:453186. [PMID: 24799897 DOI: 10.1155/2014/453186] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 1.5] [Reference Citation Analysis]
30 Suarez C, Volkmann K, Gomes AR, Billker O, Blackman MJ. The malarial serine protease SUB1 plays an essential role in parasite liver stage development. PLoS Pathog 2013;9:e1003811. [PMID: 24348254 DOI: 10.1371/journal.ppat.1003811] [Cited by in Crossref: 26] [Cited by in F6Publishing: 22] [Article Influence: 2.9] [Reference Citation Analysis]
31 Walker DM, Oghumu S, Gupta G, McGwire BS, Drew ME, Satoskar AR. Mechanisms of cellular invasion by intracellular parasites. Cell Mol Life Sci 2014;71:1245-63. [PMID: 24221133 DOI: 10.1007/s00018-013-1491-1] [Cited by in Crossref: 86] [Cited by in F6Publishing: 80] [Article Influence: 9.6] [Reference Citation Analysis]
32 Blackman MJ, Carruthers VB. Recent insights into apicomplexan parasite egress provide new views to a kill. Curr Opin Microbiol 2013;16:459-64. [PMID: 23725669 DOI: 10.1016/j.mib.2013.04.008] [Cited by in Crossref: 44] [Cited by in F6Publishing: 41] [Article Influence: 4.9] [Reference Citation Analysis]
33 Bouillon A, Giganti D, Benedet C, Gorgette O, Pêtres S, Crublet E, Girard-Blanc C, Witkowski B, Ménard D, Nilges M, Mercereau-Puijalon O, Stoven V, Barale JC. In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound. J Biol Chem 2013;288:18561-73. [PMID: 23653352 DOI: 10.1074/jbc.M113.456764] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
34 Armijos Jaramillo VD, Vargas WA, Sukno SA, Thon MR. Horizontal transfer of a subtilisin gene from plants into an ancestor of the plant pathogenic fungal genus Colletotrichum. PLoS One 2013;8:e59078. [PMID: 23554975 DOI: 10.1371/journal.pone.0059078] [Cited by in Crossref: 24] [Cited by in F6Publishing: 20] [Article Influence: 2.7] [Reference Citation Analysis]
35 Fulle S, Withers-Martinez C, Blackman MJ, Morris GM, Finn PW. Molecular determinants of binding to the Plasmodium subtilisin-like protease 1. J Chem Inf Model 2013;53:573-83. [PMID: 23414065 DOI: 10.1021/ci300581z] [Cited by in Crossref: 21] [Cited by in F6Publishing: 22] [Article Influence: 2.3] [Reference Citation Analysis]
36 Ruecker A, Shea M, Hackett F, Suarez C, Hirst EM, Milutinovic K, Withers-Martinez C, Blackman MJ. Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte. J Biol Chem 2012;287:37949-63. [PMID: 22984267 DOI: 10.1074/jbc.M112.400820] [Cited by in Crossref: 49] [Cited by in F6Publishing: 46] [Article Influence: 4.9] [Reference Citation Analysis]
37 Gemma S, Giovani S, Brindisi M, Tripaldi P, Brogi S, Savini L, Fiorini I, Novellino E, Butini S, Campiani G, Penzo M, Blackman MJ. Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1. Bioorg Med Chem Lett 2012;22:5317-21. [PMID: 22796182 DOI: 10.1016/j.bmcl.2012.06.023] [Cited by in Crossref: 21] [Cited by in F6Publishing: 20] [Article Influence: 2.1] [Reference Citation Analysis]
38 Baum J, Saliba KJ, Cooke BM. Editorial--Molecular Approaches to Malaria 2012 (MAM 2012). Int J Parasitol 2012;42:517. [PMID: 22656266 DOI: 10.1016/j.ijpara.2012.05.001] [Reference Citation Analysis]
39 Lidumniece E, Withers-Martinez C, Hackett F, Collins CR, Perrin AJ, Koussis K, Bisson C, Blackman MJ, Jirgensons A. Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1. Proc Natl Acad Sci U S A 2021;118:e2022696118. [PMID: 33975947 DOI: 10.1073/pnas.2022696118] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Reference Citation Analysis]