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For: Borner T, Shaulson ED, Ghidewon MY, Barnett AB, Horn CC, Doyle RP, Grill HJ, Hayes MR, De Jonghe BC. GDF15 Induces Anorexia through Nausea and Emesis. Cell Metab 2020;31:351-362.e5. [PMID: 31928886 DOI: 10.1016/j.cmet.2019.12.004] [Cited by in Crossref: 38] [Cited by in F6Publishing: 61] [Article Influence: 19.0] [Reference Citation Analysis]
Number Citing Articles
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11 Tanha HM, Nyholt DR; International Headache Genetics Consortium. Genetic analyses identify pleiotropy and causality for blood proteins and highlight Wnt/β-catenin signalling in migraine. Nat Commun 2022;13:2593. [PMID: 35546551 DOI: 10.1038/s41467-022-30184-z] [Reference Citation Analysis]
12 Lu Z, Cui D, Liu JYH, Jiang B, Ngan MP, Sakata I, Takemi S, Sakai T, Lin G, Chan SW, Rudd JA. The Actions of Centrally Administered Nesfatin-1 on Emesis, Feeding, and Locomotor Activity in Suncus murinus (House Musk Shrew). Front Pharmacol 2022;13:858522. [DOI: 10.3389/fphar.2022.858522] [Reference Citation Analysis]
13 Albuquerque B, Chen X, Hirenallur-Shanthappa D, Zhao Y, Stansfield JC, Zhang BB, Sheikh A, Wu Z. Neutralization of GDF15 Prevents Anorexia and Weight Loss in the Monocrotaline-Induced Cardiac Cachexia Rat Model. Cells 2022;11:1073. [PMID: 35406637 DOI: 10.3390/cells11071073] [Cited by in Crossref: 2] [Article Influence: 2.0] [Reference Citation Analysis]
14 Zhao YZ, Dai YZ, Nie K. Research Progress on the Antiemetic Effect of Traditional Chinese Medicine Against Chemotherapy-Induced Nausea and Vomiting: A Review. Front Pharmacol 2021;12:790784. [PMID: 35222008 DOI: 10.3389/fphar.2021.790784] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
15 Dai Y, Chen S, Li Y, Zhang G, Bi P, Nie K. Liujunzi Decoction ameliorated cisplatin-induced anorexia by inhibiting the JAK-STAT signaling pathway and coordinating anorexigenic and orexigenic neuropeptides in rats. J Ethnopharmacol 2022;285:114840. [PMID: 34800646 DOI: 10.1016/j.jep.2021.114840] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
16 Fejzo MS, MacGibbon KW, First O, Quan C, Mullin PM. Whole-exome sequencing uncovers new variants in GDF15 associated with hyperemesis gravidarum. BJOG 2022. [PMID: 35218128 DOI: 10.1111/1471-0528.17129] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
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18 Sarkar S, Melchior JT, Henry HR, Syed F, Mirmira RG, Nakayasu ES, Metz TO. GDF15: a potential therapeutic target for type 1 diabetes. Expert Opin Ther Targets 2022;:1-11. [PMID: 35138971 DOI: 10.1080/14728222.2022.2029410] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 4.0] [Reference Citation Analysis]
19 Lutz TA. Creating the amylin story. Appetite 2022. [DOI: 10.1016/j.appet.2022.105965] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
20 Lu JF, Zhu MQ, Xie BC, Shi XC, Liu H, Zhang RX, Xia B, Wu JW. Camptothecin effectively treats obesity in mice through GDF15 induction. PLoS Biol 2022;20:e3001517. [PMID: 35202387 DOI: 10.1371/journal.pbio.3001517] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
21 Xiao QA, He Q, Zeng J, Xia X. GDF-15, a future therapeutic target of glucolipid metabolic disorders and cardiovascular disease. Biomed Pharmacother 2021;146:112582. [PMID: 34959119 DOI: 10.1016/j.biopha.2021.112582] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
22 Tu L, Liu JYH, Lu Z, Cui D, Ngan MP, Du P, Rudd JA. Insights Into Acute and Delayed Cisplatin-Induced Emesis From a Microelectrode Array, Radiotelemetry and Whole-Body Plethysmography Study of Suncus murinus (House Musk Shrew). Front Pharmacol 2021;12:746053. [PMID: 34925008 DOI: 10.3389/fphar.2021.746053] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
23 Reiner BC, Crist RC, Borner T, Doyle RP, Hayes MR, De Jonghe BC. Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment. Mol Metab 2021;:101422. [PMID: 34942400 DOI: 10.1016/j.molmet.2021.101422] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
24 Kim TH, Hong DG, Yang YM. Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism. Biomedicines 2021;9:1903. [PMID: 34944728 DOI: 10.3390/biomedicines9121903] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
25 Gaafer OU, Zimmers TA. Nutrition challenges of cancer cachexia. JPEN J Parenter Enteral Nutr 2021;45:16-25. [PMID: 34897740 DOI: 10.1002/jpen.2287] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
26 Ala M, Ala M. Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next? ACS Pharmacol Transl Sci 2021;4:1747-70. [PMID: 34927008 DOI: 10.1021/acsptsci.1c00167] [Cited by in F6Publishing: 4] [Reference Citation Analysis]
27 Müller TD, Blüher M, Tschöp MH, DiMarchi RD. Anti-obesity drug discovery: advances and challenges. Nat Rev Drug Discov 2021. [PMID: 34815532 DOI: 10.1038/s41573-021-00337-8] [Cited by in F6Publishing: 46] [Reference Citation Analysis]
28 Johann K, Kleinert M, Klaus S. The Role of GDF15 as a Myomitokine. Cells 2021;10:2990. [PMID: 34831213 DOI: 10.3390/cells10112990] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 6.0] [Reference Citation Analysis]
29 Jiang WW, Zhang ZZ, He PP, Jiang LP, Chen JZ, Zhang XT, Hu M, Zhang YK, Ouyang XP. Emerging roles of growth differentiation factor-15 in brain disorders (Review). Exp Ther Med 2021;22:1270. [PMID: 34594407 DOI: 10.3892/etm.2021.10705] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
30 Jansen LAW, Koot MH, Van't Hooft J, Dean CR, Bossuyt PMM, Ganzevoort W, Gauw N, Van der Goes BY, Rodenburg J, Roseboom TJ, Painter RC, Grooten IJ. The windsor definition for hyperemesis gravidarum: A multistakeholder international consensus definition. Eur J Obstet Gynecol Reprod Biol 2021;266:15-22. [PMID: 34555550 DOI: 10.1016/j.ejogrb.2021.09.004] [Cited by in F6Publishing: 6] [Reference Citation Analysis]
31 Wang D, Day EA, Townsend LK, Djordjevic D, Jørgensen SB, Steinberg GR. GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease. Nat Rev Endocrinol 2021. [PMID: 34381196 DOI: 10.1038/s41574-021-00529-7] [Cited by in Crossref: 33] [Cited by in F6Publishing: 30] [Article Influence: 33.0] [Reference Citation Analysis]
32 Olson B, Diba P, Korzun T, Marks DL. Neural Mechanisms of Cancer Cachexia. Cancers (Basel) 2021;13:3990. [PMID: 34439145 DOI: 10.3390/cancers13163990] [Cited by in Crossref: 1] [Cited by in F6Publishing: 7] [Article Influence: 1.0] [Reference Citation Analysis]
33 Sabatini PV, Frikke-Schmidt H, Arthurs J, Gordian D, Patel A, Rupp AC, Adams JM, Wang J, Beck Jørgensen S, Olson DP, Palmiter RD, Myers MG Jr, Seeley RJ. GFRAL-expressing neurons suppress food intake via aversive pathways. Proc Natl Acad Sci U S A 2021;118:e2021357118. [PMID: 33593916 DOI: 10.1073/pnas.2021357118] [Cited by in Crossref: 4] [Cited by in F6Publishing: 17] [Article Influence: 4.0] [Reference Citation Analysis]
34 Seyfried F, Hoffmann A, Rullmann M, Schlegel N, Otto C, Hankir MK. Weight loss from caloric restriction vs Roux-en-Y gastric bypass surgery differentially regulates systemic and portal vein GDF15 levels in obese Zucker fatty rats. Physiol Behav 2021;240:113534. [PMID: 34303715 DOI: 10.1016/j.physbeh.2021.113534] [Reference Citation Analysis]
35 Lockhart SM, Saudek V, O'Rahilly S. GDF15: A Hormone Conveying Somatic Distress to the Brain. Endocr Rev 2020;41:bnaa007. [PMID: 32310257 DOI: 10.1210/endrev/bnaa007] [Cited by in Crossref: 24] [Cited by in F6Publishing: 47] [Article Influence: 24.0] [Reference Citation Analysis]
36 Kim M, Walston JD, Won CW. Associations between elevated growth differentiation factor-15 and sarcopenia among community-dwelling older adults. J Gerontol A Biol Sci Med Sci 2021:glab201. [PMID: 34255062 DOI: 10.1093/gerona/glab201] [Cited by in Crossref: 1] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
37 Cimino I, Kim H, Tung YCL, Pedersen K, Rimmington D, Tadross JA, Kohnke SN, Neves-Costa A, Barros A, Joaquim S, Bennett D, Melvin A, Lockhart SM, Rostron AJ, Scott J, Liu H, Burling K, Barker P, Clatworthy MR, Lee EC, Simpson AJ, Yeo GSH, Moita LF, Bence KK, Jørgensen SB, Coll AP, Breen DM, O'Rahilly S. Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15. Proc Natl Acad Sci U S A 2021;118:e2106868118. [PMID: 34187898 DOI: 10.1073/pnas.2106868118] [Cited by in F6Publishing: 9] [Reference Citation Analysis]
38 Zhong W, Shahbaz O, Teskey G, Beever A, Kachour N, Venketaraman V, Darmani NA. Mechanisms of Nausea and Vomiting: Current Knowledge and Recent Advances in Intracellular Emetic Signaling Systems. Int J Mol Sci 2021;22:5797. [PMID: 34071460 DOI: 10.3390/ijms22115797] [Cited by in F6Publishing: 11] [Reference Citation Analysis]
39 Borner T, Wald HS, Ghidewon MY, Zhang B, Wu Z, De Jonghe BC, Breen D, Grill HJ. GDF15 Induces an Aversive Visceral Malaise State that Drives Anorexia and Weight Loss. Cell Rep 2020;31:107543. [PMID: 32320650 DOI: 10.1016/j.celrep.2020.107543] [Cited by in Crossref: 13] [Cited by in F6Publishing: 27] [Article Influence: 13.0] [Reference Citation Analysis]
40 Fung E, Kang L, Sapashnik D, Benard S, Sievers A, Liu Y, Yan G, Zhou J, Rodriguez L, Ma W, Stochaj WR, LaVallie E, Wroblewska L, Kelleher K, Tam A, Bezy O, Breen D, Chabot JR, He T, Lin L, Wu Z, Mosyak L. Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation. Sci Rep 2021;11:8921. [PMID: 33903632 DOI: 10.1038/s41598-021-87959-5] [Cited by in Crossref: 1] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
41 Lercher A, Baazim H, Bergthaler A. Systemic Immunometabolism: Challenges and Opportunities. Immunity 2020;53:496-509. [PMID: 32937151 DOI: 10.1016/j.immuni.2020.08.012] [Cited by in Crossref: 12] [Cited by in F6Publishing: 28] [Article Influence: 12.0] [Reference Citation Analysis]
42 Klein AB, Nicolaisen TS, Ørtenblad N, Gejl KD, Jensen R, Fritzen AM, Larsen EL, Karstoft K, Poulsen HE, Morville T, Sahl RE, Helge JW, Lund J, Falk S, Lyngbæk M, Ellingsgaard H, Pedersen BK, Lu W, Finan B, Jørgensen SB, Seeley RJ, Kleinert M, Kiens B, Richter EA, Clemmensen C. Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise. Nat Commun 2021;12:1041. [PMID: 33589633 DOI: 10.1038/s41467-021-21309-x] [Cited by in Crossref: 8] [Cited by in F6Publishing: 25] [Article Influence: 8.0] [Reference Citation Analysis]
43 Hasanpour Segherlou Z, Nouri-Vaskeh M, Noroozi Guilandehi S, Baghbanzadeh A, Zand R, Baradaran B, Zarei M. GDF-15: Diagnostic, prognostic, and therapeutic significance in glioblastoma multiforme. J Cell Physiol 2021;236:5564-81. [PMID: 33580506 DOI: 10.1002/jcp.30289] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
44 Kang SG, Choi MJ, Jung SB, Chung HK, Chang JY, Kim JT, Kang YE, Lee JH, Hong HJ, Jun SM, Ro HJ, Suh JM, Kim H, Auwerx J, Yi HS, Shong M. Differential roles of GDF15 and FGF21 in systemic metabolic adaptation to the mitochondrial integrated stress response. iScience 2021;24:102181. [PMID: 33718833 DOI: 10.1016/j.isci.2021.102181] [Cited by in Crossref: 3] [Cited by in F6Publishing: 17] [Article Influence: 3.0] [Reference Citation Analysis]
45 Klaus S, Igual Gil C, Ost M. Regulation of diurnal energy balance by mitokines. Cell Mol Life Sci 2021;78:3369-84. [PMID: 33464381 DOI: 10.1007/s00018-020-03748-9] [Cited by in Crossref: 3] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
46 Rausch V, Sala V, Penna F, Porporato PE, Ghigo A. Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia. Oncogenesis 2021;10:1. [PMID: 33419963 DOI: 10.1038/s41389-020-00288-6] [Cited by in Crossref: 10] [Cited by in F6Publishing: 19] [Article Influence: 10.0] [Reference Citation Analysis]
47 Ahmed DS, Isnard S, Lin J, Routy B, Routy JP. GDF15/GFRAL Pathway as a Metabolic Signature for Cachexia in Patients with Cancer. J Cancer 2021;12:1125-32. [PMID: 33442410 DOI: 10.7150/jca.50376] [Cited by in Crossref: 1] [Cited by in F6Publishing: 12] [Article Influence: 1.0] [Reference Citation Analysis]
48 Molfino A, Amabile MI, Imbimbo G, Rizzo V, Pediconi F, Catalano C, Emiliani A, Belli R, Ramaccini C, Parisi C, Nigri G, Muscaritoli M. Association between Growth Differentiation Factor-15 (GDF-15) Serum Levels, Anorexia and Low Muscle Mass among Cancer Patients. Cancers (Basel) 2020;13:E99. [PMID: 33396237 DOI: 10.3390/cancers13010099] [Cited by in Crossref: 1] [Cited by in F6Publishing: 7] [Article Influence: 0.5] [Reference Citation Analysis]
49 Kim KH, Lee MS. GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH. Biochim Biophys Acta Gen Subj 2021;1865:129834. [PMID: 33358864 DOI: 10.1016/j.bbagen.2020.129834] [Cited by in F6Publishing: 10] [Reference Citation Analysis]
50 Zhou Q, Guo H, Yu C, Huang XR, Liang L, Zhang P, Yu J, Zhang J, Chan TF, Ma RCW, Lan HY. Identification of Smad3-related transcriptomes in type-2 diabetic nephropathy by whole transcriptome RNA sequencing. J Cell Mol Med 2021;25:2052-68. [PMID: 33369170 DOI: 10.1111/jcmm.16133] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
51 Jensen-Cody SO, Potthoff MJ. Hepatokines and metabolism: Deciphering communication from the liver. Mol Metab 2021;44:101138. [PMID: 33285302 DOI: 10.1016/j.molmet.2020.101138] [Cited by in Crossref: 7] [Cited by in F6Publishing: 27] [Article Influence: 3.5] [Reference Citation Analysis]
52 Zhang C, Kaye JA, Cai Z, Wang Y, Prescott SL, Liberles SD. Area Postrema Cell Types that Mediate Nausea-Associated Behaviors. Neuron 2021;109:461-472.e5. [PMID: 33278342 DOI: 10.1016/j.neuron.2020.11.010] [Cited by in Crossref: 7] [Cited by in F6Publishing: 26] [Article Influence: 3.5] [Reference Citation Analysis]
53 Breen DM, Kim H, Bennett D, Calle RA, Collins S, Esquejo RM, He T, Joaquim S, Joyce A, Lambert M, Lin L, Pettersen B, Qiao S, Rossulek M, Weber G, Wu Z, Zhang BB, Birnbaum MJ. GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates. Cell Metab 2020;32:938-950.e6. [PMID: 33207247 DOI: 10.1016/j.cmet.2020.10.023] [Cited by in Crossref: 4] [Cited by in F6Publishing: 26] [Article Influence: 2.0] [Reference Citation Analysis]
54 Wyart E, Bindels LB, Mina E, Menga A, Stanga S, Porporato PE. Cachexia, a Systemic Disease beyond Muscle Atrophy. Int J Mol Sci 2020;21:E8592. [PMID: 33202621 DOI: 10.3390/ijms21228592] [Cited by in Crossref: 2] [Cited by in F6Publishing: 8] [Article Influence: 1.0] [Reference Citation Analysis]
55 Rochette L, Zeller M, Cottin Y, Vergely C. Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic Targets. Trends Endocrinol Metab 2020;31:939-51. [PMID: 33172749 DOI: 10.1016/j.tem.2020.10.004] [Cited by in Crossref: 3] [Cited by in F6Publishing: 25] [Article Influence: 1.5] [Reference Citation Analysis]
56 Lindberg R, Lindqvist M, Trupp M, Vinnars MT, Nording ML. Polyunsaturated Fatty Acids and Their Metabolites in Hyperemesis Gravidarum. Nutrients 2020;12:E3384. [PMID: 33158081 DOI: 10.3390/nu12113384] [Reference Citation Analysis]
57 Andrews PLR, Cai W, Rudd JA, Sanger GJ. COVID-19, nausea, and vomiting. J Gastroenterol Hepatol. 2021;36:646-656. [PMID: 32955126 DOI: 10.1111/jgh.15261] [Cited by in Crossref: 8] [Cited by in F6Publishing: 18] [Article Influence: 4.0] [Reference Citation Analysis]
58 Zhao J, Pei L. Cardiac Endocrinology: Heart-Derived Hormones in Physiology and Disease. JACC Basic Transl Sci 2020;5:949-60. [PMID: 33015416 DOI: 10.1016/j.jacbts.2020.05.007] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
59 Van Dyck L, Gunst J, Casaer MP, Peeters B, Derese I, Wouters PJ, de Zegher F, Vanhorebeek I, Van den Berghe G. The clinical potential of GDF15 as a "ready-to-feed indicator" for critically ill adults. Crit Care 2020;24:557. [PMID: 32928255 DOI: 10.1186/s13054-020-03254-1] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
60 Worth AA, Shoop R, Tye K, Feetham CH, D'Agostino G, Dodd GT, Reimann F, Gribble FM, Beebe EC, Dunbar JD, Alexander-Chacko JT, Sindelar DK, Coskun T, Emmerson PJ, Luckman SM. The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling. Elife 2020;9:e55164. [PMID: 32723474 DOI: 10.7554/eLife.55164] [Cited by in Crossref: 10] [Cited by in F6Publishing: 22] [Article Influence: 5.0] [Reference Citation Analysis]
61 Borner T, Shaulson ED, Tinsley IC, Stein LM, Horn CC, Hayes MR, Doyle RP, De Jonghe BC. A second-generation glucagon-like peptide-1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models. Diabetes Obes Metab 2020;22:1729-41. [PMID: 32410372 DOI: 10.1111/dom.14089] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
62 Li W, Li C, Zhou X, Jiang T, Guo L, Liu H. Relationship between GDF15 level and bone metabolism in postmenopausal Chinese women. Gynecol Endocrinol 2020;36:714-7. [PMID: 32436412 DOI: 10.1080/09513590.2020.1764929] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
63 Morris A. Advances in GDF15 research. Nat Rev Endocrinol 2020;16:129. [PMID: 31988489 DOI: 10.1038/s41574-020-0327-y] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]