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For: Savardi A, Borgogno M, Narducci R, La Sala G, Ortega JA, Summa M, Armirotti A, Bertorelli R, Contestabile A, De Vivo M, Cancedda L. Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders. Chem 2020;6:2073-96. [PMID: 32818158 DOI: 10.1016/j.chempr.2020.06.017] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 6.5] [Reference Citation Analysis]
Number Citing Articles
1 Hui KK, Chater TE, Goda Y, Tanaka M. How Staying Negative Is Good for the (Adult) Brain: Maintaining Chloride Homeostasis and the GABA-Shift in Neurological Disorders. Front Mol Neurosci 2022;15:893111. [DOI: 10.3389/fnmol.2022.893111] [Reference Citation Analysis]
2 Colini Baldeschi A, Zattoni M, Vanni S, Nikolic L, Ferracin C, La Sala G, Summa M, Bertorelli R, Bertozzi SM, Giachin G, Carloni P, Bolognesi ML, De Vivo M, Legname G. Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance. J Med Chem 2022. [PMID: 35771181 DOI: 10.1021/acs.jmedchem.2c00205] [Reference Citation Analysis]
3 Capsoni S, Arisi I, Malerba F, D'Onofrio M, Cattaneo A, Cherubini E. Targeting the Cation-Chloride Co-Transporter NKCC1 to Re-Establish GABAergic Inhibition and an Appropriate Excitatory/Inhibitory Balance in Selective Neuronal Circuits: A Novel Approach for the Treatment of Alzheimer's Disease. Brain Sci 2022;12:783. [PMID: 35741668 DOI: 10.3390/brainsci12060783] [Reference Citation Analysis]
4 Lv H, Gu X, Shan X, Zhu T, Ma B, Zhang H, Bambini-junior V, Zhang T, Li W, Gao X, Li F. Nanoformulated Bumetanide Ameliorates Social Deficiency in BTBR Mice Model of Autism Spectrum Disorder. Front Immunol 2022;13:870577. [DOI: 10.3389/fimmu.2022.870577] [Reference Citation Analysis]
5 Zhao Y, Roy K, Vidossich P, Cancedda L, De Vivo M, Forbush B, Cao E. Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide. Nat Commun 2022;13:2747. [PMID: 35585053 DOI: 10.1038/s41467-022-30407-3] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
6 Fan S, Chen W, Chen L, Li L. CRTH2: a potential target for the treatment of organ fibrosis. Acta Biochim Biophys Sin (Shanghai) 2022;54:590-2. [PMID: 35607966 DOI: 10.3724/abbs.2022025] [Reference Citation Analysis]
7 Szymanski J, Minichiello L. NKCC1 Deficiency in Forming Hippocampal Circuits Triggers Neurodevelopmental Disorder: Role of BDNF-TrkB Signalling. Brain Sciences 2022;12:502. [DOI: 10.3390/brainsci12040502] [Reference Citation Analysis]
8 Serranilla M, Woodin MA. Striatal Chloride Dysregulation and Impaired GABAergic Signaling Due to Cation-Chloride Cotransporter Dysfunction in Huntington’s Disease. Front Cell Neurosci 2022;15:817013. [DOI: 10.3389/fncel.2021.817013] [Reference Citation Analysis]
9 Verma V, Kumar MJV, Sharma K, Rajaram S, Muddashetty R, Manjithaya R, Behnisch T, Clement JP. Pharmacological intervention in young adolescents rescues synaptic physiology and behavioural deficits in Syngap1+/- mice. Exp Brain Res 2021. [PMID: 34739555 DOI: 10.1007/s00221-021-06254-x] [Reference Citation Analysis]
10 Xue JY, Grigelioniene G, Wang Z, Nishimura G, Iida A, Matsumoto N, Tham E, Miyake N, Ikegawa S, Guo L. SLC4A2 Deficiency Causes a New Type of Osteopetrosis. J Bone Miner Res 2021. [PMID: 34668226 DOI: 10.1002/jbmr.4462] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
11 Savardi A, Borgogno M, De Vivo M, Cancedda L. Pharmacological tools to target NKCC1 in brain disorders. Trends Pharmacol Sci 2021;42:1009-34. [PMID: 34620512 DOI: 10.1016/j.tips.2021.09.005] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
12 Portioli C, Ruiz Munevar MJ, De Vivo M, Cancedda L. Cation-coupled chloride cotransporters: chemical insights and disease implications. Trends Chem 2021;3:832-49. [PMID: 34604727 DOI: 10.1016/j.trechm.2021.05.004] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
13 Abruzzo PM, Panisi C, Marini M. The Alteration of Chloride Homeostasis/GABAergic Signaling in Brain Disorders: Could Oxidative Stress Play a Role? Antioxidants (Basel) 2021;10:1316. [PMID: 34439564 DOI: 10.3390/antiox10081316] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
14 Borgogno M, Savardi A, Manigrasso J, Turci A, Portioli C, Ottonello G, Bertozzi SM, Armirotti A, Contestabile A, Cancedda L, De Vivo M. Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome. J Med Chem 2021;64:10203-29. [PMID: 34137257 DOI: 10.1021/acs.jmedchem.1c00603] [Reference Citation Analysis]
15 Parrini M, Naskar S, Alberti M, Colombi I, Morelli G, Rocchi A, Nanni M, Piccardi F, Charles S, Ronzitti G, Mingozzi F, Contestabile A, Cancedda L. Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome. Mol Ther 2021:S1525-0016(21)00305-1. [PMID: 34058387 DOI: 10.1016/j.ymthe.2021.05.023] [Reference Citation Analysis]
16 Tang X, Jaenisch R, Sur M. The role of GABAergic signalling in neurodevelopmental disorders. Nat Rev Neurosci 2021;22:290-307. [PMID: 33772226 DOI: 10.1038/s41583-021-00443-x] [Cited by in Crossref: 10] [Cited by in F6Publishing: 21] [Article Influence: 10.0] [Reference Citation Analysis]
17 Peerboom C, Wierenga CJ. The postnatal GABA shift: A developmental perspective. Neurosci Biobehav Rev 2021;124:179-92. [PMID: 33549742 DOI: 10.1016/j.neubiorev.2021.01.024] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
18 Josiah SS, Meor Azlan NF, Zhang J. Targeting the WNK-SPAK/OSR1 Pathway and Cation-Chloride Cotransporters for the Therapy of Stroke. Int J Mol Sci 2021;22:1232. [PMID: 33513812 DOI: 10.3390/ijms22031232] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 6.0] [Reference Citation Analysis]
19 Delpire E. Advances in the development of novel compounds targeting cation-chloride cotransporter physiology. Am J Physiol Cell Physiol 2021;320:C324-40. [PMID: 33356948 DOI: 10.1152/ajpcell.00566.2020] [Reference Citation Analysis]
20 Virtanen MA, Uvarov P, Hübner CA, Kaila K. NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data. Cells 2020;9:E2607. [PMID: 33291778 DOI: 10.3390/cells9122607] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
21 Koumangoye R, Bastarache L, Delpire E. NKCC1: Newly Found as a Human Disease-Causing Ion Transporter. Function (Oxf) 2021;2:zqaa028. [PMID: 33345190 DOI: 10.1093/function/zqaa028] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
22 Raveendran VA, Pressey JC, Woodin MA. A Novel Small Molecule Targets NKCC1 To Restore Synaptic Inhibition. Trends Pharmacol Sci 2020;41:897-9. [PMID: 33097285 DOI: 10.1016/j.tips.2020.10.002] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
23 Meor Azlan NF, Zhang J. Role of the Cation-Chloride-Cotransporters in Cardiovascular Disease. Cells 2020;9:E2293. [PMID: 33066544 DOI: 10.3390/cells9102293] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
24 Pinto B, Morelli G, Rastogi M, Savardi A, Fumagalli A, Petretto A, Bartolucci M, Varea E, Catelani T, Contestabile A, Perlini LE, Cancedda L. Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome. Neuron 2020;108:887-904.e12. [PMID: 33027640 DOI: 10.1016/j.neuron.2020.09.010] [Cited by in Crossref: 15] [Cited by in F6Publishing: 11] [Article Influence: 7.5] [Reference Citation Analysis]