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For: Timper K, Denson JL, Steculorum SM, Heilinger C, Engström-Ruud L, Wunderlich CM, Rose-John S, Wunderlich FT, Brüning JC. IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling. Cell Rep 2017;19:267-80. [PMID: 28402851 DOI: 10.1016/j.celrep.2017.03.043] [Cited by in Crossref: 99] [Cited by in F6Publishing: 91] [Article Influence: 19.8] [Reference Citation Analysis]
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9 Patsalos O, Dalton B, Himmerich H. Effects of IL-6 Signaling Pathway Inhibition on Weight and BMI: A Systematic Review and Meta-Analysis. Int J Mol Sci 2020;21:E6290. [PMID: 32878032 DOI: 10.3390/ijms21176290] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 2.5] [Reference Citation Analysis]
10 Ishida M, Tatsumi K, Okumoto K, Kaji H. Adipose Tissue-Derived Stem Cell Sheet Improves Glucose Metabolism in Obese Mice. Stem Cells Dev 2020;29:488-97. [PMID: 32075539 DOI: 10.1089/scd.2019.0250] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 2.5] [Reference Citation Analysis]
11 Breuer S, Kasper P, Vohlen C, Janoschek R, Hoffmann T, Appel S, Müller-Limberger E, Mesaros A, Rose-John S, Garbers C, Müller S, Lackmann JW, Mahabir E, Dötsch J, Hucklenbruch-Rother E, Bae-Gartz I. Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring. Nutrients 2021;13:3735. [PMID: 34835991 DOI: 10.3390/nu13113735] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
12 Unamuno X, Gómez-Ambrosi J, Rodríguez A, Becerril S, Frühbeck G, Catalán V. Adipokine dysregulation and adipose tissue inflammation in human obesity. Eur J Clin Invest 2018;48:e12997. [PMID: 29995306 DOI: 10.1111/eci.12997] [Cited by in F6Publishing: 119] [Reference Citation Analysis]
13 Pedersen BK. Anti-inflammatory effects of exercise: role in diabetes and cardiovascular disease. Eur J Clin Invest 2017;47:600-11. [PMID: 28722106 DOI: 10.1111/eci.12781] [Cited by in Crossref: 195] [Cited by in F6Publishing: 183] [Article Influence: 39.0] [Reference Citation Analysis]
14 Mishra D, Richard JE, Maric I, Porteiro B, Häring M, Kooijman S, Musovic S, Eerola K, López-Ferreras L, Peris E, Grycel K, Shevchouk OT, Micallef P, Olofsson CS, Wernstedt Asterholm I, Grill HJ, Nogueiras R, Skibicka KP. Parabrachial Interleukin-6 Reduces Body Weight and Food Intake and Increases Thermogenesis to Regulate Energy Metabolism. Cell Rep 2019;26:3011-3026.e5. [PMID: 30865890 DOI: 10.1016/j.celrep.2019.02.044] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 7.5] [Reference Citation Analysis]
15 Zhao Y, Suo Y, Yang Z, Hao Y, Li W, Su Y, Shi Y, Gao Y, Song L, Yin X, Shi H. Inspiration for the prevention and treatment of neuropsychiatric disorders: New insight from the bone-brain-axis. Brain Res Bull 2021;177:263-72. [PMID: 34678443 DOI: 10.1016/j.brainresbull.2021.10.009] [Reference Citation Analysis]
16 Bay ML, Pedersen BK. Muscle-Organ Crosstalk: Focus on Immunometabolism. Front Physiol 2020;11:567881. [PMID: 33013484 DOI: 10.3389/fphys.2020.567881] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 5.0] [Reference Citation Analysis]
17 Balakrishnan R, Thurmond DC. Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance. Int J Mol Sci 2022;23:4636. [PMID: 35563026 DOI: 10.3390/ijms23094636] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
18 Robb JL, Morrissey NA, Weightman Potter PG, Smithers HE, Beall C, Ellacott KLJ. Immunometabolic Changes in Glia - A Potential Role in the Pathophysiology of Obesity and Diabetes. Neuroscience 2020;447:167-81. [PMID: 31765625 DOI: 10.1016/j.neuroscience.2019.10.021] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 2.3] [Reference Citation Analysis]
19 Giraldez MD, Carneros D, Garbers C, Rose-John S, Bustos M. New insights into IL-6 family cytokines in metabolism, hepatology and gastroenterology. Nat Rev Gastroenterol Hepatol 2021. [PMID: 34211157 DOI: 10.1038/s41575-021-00473-x] [Cited by in Crossref: 17] [Cited by in F6Publishing: 13] [Article Influence: 17.0] [Reference Citation Analysis]
20 Mcneilly AD, Yianakas A, Gallagher JG, Tarlton J, Ashford ML, Mccrimmon RJ. Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion. Molecular Metabolism 2022. [DOI: 10.1016/j.molmet.2022.101488] [Reference Citation Analysis]
21 Wang J, Zhao D, Ding CZ, Guo F, Wu LN, Huang FJ, Liu YL, Zhao SY, Xin Y, Ma SN, Ji HF, Wang X, Wei LR. MicroRNA-194: a novel regulator of glucagon-like peptide-1 synthesis in intestinal L cells. Cell Death Dis 2021;12:113. [PMID: 33479193 DOI: 10.1038/s41419-020-03366-0] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
22 Ullah R, Rauf N, Nabi G, Yi S, Yu-Dong Z, Fu J. Mechanistic insight into high-fat diet-induced metabolic inflammation in the arcuate nucleus of the hypothalamus. Biomed Pharmacother 2021;142:112012. [PMID: 34388531 DOI: 10.1016/j.biopha.2021.112012] [Reference Citation Analysis]
23 Townsend LK, MacPherson REK, Wright DC. New Horizon: Exercise and a Focus on Tissue-Brain Crosstalk. J Clin Endocrinol Metab 2021;106:2147-63. [PMID: 33982072 DOI: 10.1210/clinem/dgab333] [Reference Citation Analysis]
24 Townsend LK, Medak KD, Peppler WT, Meers GM, Rector RS, LeBlanc PJ, Wright DC. High-saturated-fat diet-induced obesity causes hepatic interleukin-6 resistance via endoplasmic reticulum stress. J Lipid Res 2019;60:1236-49. [PMID: 31085628 DOI: 10.1194/jlr.M092510] [Cited by in Crossref: 18] [Cited by in F6Publishing: 8] [Article Influence: 6.0] [Reference Citation Analysis]
25 Anesten F, Santos C, Gidestrand E, Schéle E, Pálsdóttir V, Swedung-Wettervik T, Meister B, Patrycja Skibicka K, Jansson JO. Functional interleukin-6 receptor-α is located in tanycytes at the base of the third ventricle. J Neuroendocrinol 2017;29. [PMID: 29024103 DOI: 10.1111/jne.12546] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 2.8] [Reference Citation Analysis]
26 Abdel-Raouf KMA, Rezgui R, Stefanini C, Teo JCM, Christoforou N. Transdifferentiation of Human Fibroblasts into Skeletal Muscle Cells: Optimization and Assembly into Engineered Tissue Constructs through Biological Ligands. Biology (Basel) 2021;10:539. [PMID: 34208436 DOI: 10.3390/biology10060539] [Reference Citation Analysis]
27 Álvarez-Artime A, García-Soler B, Sainz RM, Mayo JC. Emerging Roles for Browning of White Adipose Tissue in Prostate Cancer Malignant Behaviour. Int J Mol Sci 2021;22:5560. [PMID: 34074045 DOI: 10.3390/ijms22115560] [Reference Citation Analysis]
28 Arora G, Gupta A, Guo T, Gandhi A, Laine A, Williams D, Ahn C, Iyengar P, Infante R. JAK Inhibitors Suppress Cancer Cachexia-Associated Anorexia and Adipose Wasting in Mice. JCSM Rapid Commun 2020;3:115-28. [PMID: 33103159 DOI: 10.1002/rco2.24] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
29 Cansell C, Stobbe K, Sanchez C, Le Thuc O, Mosser CA, Ben-Fradj S, Leredde J, Lebeaupin C, Debayle D, Fleuriot L, Brau F, Devaux N, Benani A, Audinat E, Blondeau N, Nahon JL, Rovère C. Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein-positive cells and microglia in male mice. Glia 2021;69:42-60. [PMID: 32659044 DOI: 10.1002/glia.23882] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
30 Villar-Fincheira P, Sanhueza-Olivares F, Norambuena-Soto I, Cancino-Arenas N, Hernandez-Vargas F, Troncoso R, Gabrielli L, Chiong M. Role of Interleukin-6 in Vascular Health and Disease. Front Mol Biosci 2021;8:641734. [PMID: 33786327 DOI: 10.3389/fmolb.2021.641734] [Cited by in Crossref: 3] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
31 Buie JJ, Watson LS, Smith CJ, Sims-Robinson C. Obesity-related cognitive impairment: The role of endothelial dysfunction. Neurobiol Dis 2019;132:104580. [PMID: 31454547 DOI: 10.1016/j.nbd.2019.104580] [Cited by in Crossref: 16] [Cited by in F6Publishing: 18] [Article Influence: 5.3] [Reference Citation Analysis]
32 de Guia RM, Hassing AS, Skov LJ, Ratner C, Plucińska K, Madsen S, Diep TA, Dela Cruz GV, Trammell SAJ, Sustarsic EG, Emanuelli B, Gillum MP, Gerhart-Hines Z, Holst B, Treebak JT. Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus. Acta Physiol (Oxf) 2020;228:e13437. [PMID: 31900990 DOI: 10.1111/apha.13437] [Cited by in Crossref: 7] [Cited by in F6Publishing: 12] [Article Influence: 3.5] [Reference Citation Analysis]
33 Li L, Duan C, Zhao Y, Zhang X, Yin H, Wang T, Huang C, Liu S, Yang S, Li X. Preventive effects of interleukin-6 in lipopolysaccharide/ d -galactosamine induced acute liver injury via regulating inflammatory response in hepatic macrophages. International Immunopharmacology 2017;51:99-106. [DOI: 10.1016/j.intimp.2017.08.009] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 4.4] [Reference Citation Analysis]
34 López-Ferreras L, Longo F, Richard JE, Eerola K, Shevchouk OT, Tuzinovic M, Skibicka KP. Key role for hypothalamic interleukin-6 in food-motivated behavior and body weight regulation. Psychoneuroendocrinology 2021;131:105284. [PMID: 34090139 DOI: 10.1016/j.psyneuen.2021.105284] [Reference Citation Analysis]
35 Jiang H, Gallet S, Klemm P, Scholl P, Folz-Donahue K, Altmüller J, Alber J, Heilinger C, Kukat C, Loyens A, Müller-Fielitz H, Sundaram S, Schwaninger M, Prevot V, Brüning JC. MCH Neurons Regulate Permeability of the Median Eminence Barrier. Neuron 2020;107:306-319.e9. [PMID: 32407670 DOI: 10.1016/j.neuron.2020.04.020] [Cited by in Crossref: 13] [Cited by in F6Publishing: 10] [Article Influence: 6.5] [Reference Citation Analysis]
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37 Méndez-García LA, Cid-Soto M, Aguayo-Guerrero JA, Carrero-Aguirre M, Trejo-Millán F, Islas-Andrade S, Fragoso JM, Olivos-García A, Escobedo G. Low Serum Interleukin-6 Is a Differential Marker of Obesity-Related Metabolic Dysfunction in Women and Men. J Interferon Cytokine Res 2020;40:131-8. [PMID: 31944871 DOI: 10.1089/jir.2019.0149] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
38 Rahman MH, Bhusal A, Lee W, Lee I, Suk K. Hypothalamic inflammation and malfunctioning glia in the pathophysiology of obesity and diabetes: Translational significance. Biochemical Pharmacology 2018;153:123-33. [DOI: 10.1016/j.bcp.2018.01.024] [Cited by in Crossref: 18] [Cited by in F6Publishing: 16] [Article Influence: 4.5] [Reference Citation Analysis]
39 Moghbeli M, Khedmatgozar H, Yadegari M, Avan A, Ferns GA, Ghayour Mobarhan M. Cytokines and the immune response in obesity-related disorders. Adv Clin Chem 2021;101:135-68. [PMID: 33706888 DOI: 10.1016/bs.acc.2020.06.004] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
40 Lu Z, Li Y, Song J. Characterization and Treatment of Inflammation and Insulin Resistance in Obese Adipose Tissue. Diabetes Metab Syndr Obes 2020;13:3449-60. [PMID: 33061505 DOI: 10.2147/DMSO.S271509] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
41 Reilly SM, Abu-Odeh M, Ameka M, DeLuca JH, Naber MC, Dadpey B, Ebadat N, Gomez AV, Peng X, Poirier B, Walk E, Potthoff MJ, Saltiel AR. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition. J Clin Invest 2021;131:145546. [PMID: 33822771 DOI: 10.1172/JCI145546] [Reference Citation Analysis]
42 Lettieri-Barbato D, Aquilano K. Aging and Immunometabolic Adaptations to Thermogenesis. Ageing Res Rev 2020;63:101143. [PMID: 32810648 DOI: 10.1016/j.arr.2020.101143] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
43 Rajendran S, Anquetil F, Quesada-Masachs E, Graef M, Gonzalez N, McArdle S, Chu T, Krogvold L, Dahl-Jørgensen K, von Herrath M. IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes. Clin Immunol 2020;211:108320. [PMID: 31809899 DOI: 10.1016/j.clim.2019.108320] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 3.0] [Reference Citation Analysis]
44 Albrecht C, Cittadini MC, Soria EA. Pharmacological Activity of Quercetin and 5 Caffeoylquinic Acid Oral Intake in Male Balb/c Mice with Lung Adenocarcinoma. Arch Med Res 2020;51:8-12. [PMID: 32086110 DOI: 10.1016/j.arcmed.2019.11.006] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
45 Lombardo M, Feraco A, Bellia C, Prisco L, D’ippolito I, Padua E, Storz MA, Lauro D, Caprio M, Bellia A. Influence of Nutritional Status and Physical Exercise on Immune Response in Metabolic Syndrome. Nutrients 2022;14:2054. [DOI: 10.3390/nu14102054] [Reference Citation Analysis]
46 Linnemann AK, Blumer J, Marasco MR, Battiola TJ, Umhoefer HM, Han JY, Lamming DW, Davis DB. Interleukin 6 protects pancreatic β cells from apoptosis by stimulation of autophagy. FASEB J 2017;31:4140-52. [PMID: 28592636 DOI: 10.1096/fj.201700061RR] [Cited by in Crossref: 45] [Cited by in F6Publishing: 26] [Article Influence: 9.0] [Reference Citation Analysis]
47 Timper K, Del Río-Martín A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, Horvath TL, Kloppenburg P, Backes H, Brüning JC. GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function. Cell Metab 2020;31:1189-1205.e13. [PMID: 32433922 DOI: 10.1016/j.cmet.2020.05.001] [Cited by in Crossref: 14] [Cited by in F6Publishing: 15] [Article Influence: 7.0] [Reference Citation Analysis]
48 Li X, Qiu W, Li N, Da X, Ma Q, Hou Y, Wang T, Song M, Chen J. Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling. Front Psychiatry 2020;11:557. [PMID: 32655424 DOI: 10.3389/fpsyt.2020.00557] [Reference Citation Analysis]
49 Drutskaya MS, Efimov GA, Kruglov AA, Nedospasov SA. Can we design a better anti‐cytokine therapy? J Leuk Biol 2017;102:783-90. [DOI: 10.1189/jlb.3ma0117-025r] [Cited by in Crossref: 14] [Cited by in F6Publishing: 6] [Article Influence: 2.8] [Reference Citation Analysis]
50 Yu H, Dilbaz S, Coßmann J, Hoang AC, Diedrich V, Herwig A, Harauma A, Hoshi Y, Moriguchi T, Landgraf K, Körner A, Lucas C, Brodesser S, Balogh L, Thuróczy J, Karemore G, Kuefner MS, Park EA, Rapp C, Travers JB, Röszer T. Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages. J Clin Invest 2019;129:2485-99. [PMID: 31081799 DOI: 10.1172/JCI125646] [Cited by in Crossref: 43] [Cited by in F6Publishing: 22] [Article Influence: 14.3] [Reference Citation Analysis]
51 Lehrskov LL, Christensen RH. The role of interleukin-6 in glucose homeostasis and lipid metabolism. Semin Immunopathol 2019;41:491-9. [PMID: 31101976 DOI: 10.1007/s00281-019-00747-2] [Cited by in Crossref: 16] [Cited by in F6Publishing: 14] [Article Influence: 5.3] [Reference Citation Analysis]
52 Cai D, Khor S. "Hypothalamic Microinflammation" Paradigm in Aging and Metabolic Diseases. Cell Metab 2019;30:19-35. [PMID: 31269425 DOI: 10.1016/j.cmet.2019.05.021] [Cited by in Crossref: 39] [Cited by in F6Publishing: 33] [Article Influence: 19.5] [Reference Citation Analysis]
53 Pedersen BK. Physical activity and muscle-brain crosstalk. Nat Rev Endocrinol. 2019;15:383-392. [PMID: 30837717 DOI: 10.1038/s41574-019-0174-x] [Cited by in Crossref: 224] [Cited by in F6Publishing: 183] [Article Influence: 74.7] [Reference Citation Analysis]
54 Peppler WT, Townsend LK, Wright DC. Recent advances in the role of interleukin-6 in health and disease. Current Opinion in Pharmacology 2020;52:47-51. [DOI: 10.1016/j.coph.2020.04.010] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
55 Qin C, Li J, Tang K. The Paraventricular Nucleus of the Hypothalamus: Development, Function, and Human Diseases. Endocrinology 2018;159:3458-72. [PMID: 30052854 DOI: 10.1210/en.2018-00453] [Cited by in Crossref: 29] [Cited by in F6Publishing: 24] [Article Influence: 9.7] [Reference Citation Analysis]
56 Maculewicz E, Antkowiak B, Antkowiak O, Mastalerz A, Białek A, Cywińska A, Borecka A, Humińska-Lisowska K, Garbacz A, Lorenz K, Szarska E, Michałowska-Sawczyn M, Dziuda Ł, Cięszczyk P. IL-6 Polymorphisms Are Not Related to Obesity Parameters in Physically Active Young Men. Genes (Basel) 2021;12:1498. [PMID: 34680892 DOI: 10.3390/genes12101498] [Reference Citation Analysis]
57 Kistner TM, Pedersen BK, Lieberman DE. Interleukin 6 as an energy allocator in muscle tissue. Nat Metab 2022. [PMID: 35210610 DOI: 10.1038/s42255-022-00538-4] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 8.0] [Reference Citation Analysis]
58 Anesten F, Dalmau Gasull A, Richard JE, Farkas I, Mishra D, Taing L, Zhang F, Poutanen M, Palsdottir V, Liposits Z, Skibicka KP, Jansson JO. Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1 receptor. J Neuroendocrinol 2019;31:e12722. [PMID: 31033078 DOI: 10.1111/jne.12722] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
59 Li Y, Ren H, Cao J. Roles of Interleukin-6-mediated immunometabolic reprogramming in COVID-19 and other viral infection-associated diseases. International Immunopharmacology 2022. [DOI: 10.1016/j.intimp.2022.109005] [Reference Citation Analysis]
60 Yu X, Chen Y, Liu X, Bai X, Liu K, Fu L, Gao H, Sun T, Shi X, Qi J, Li Y, Kang Y. Beneficial effects of metformin supplementation in hypothalamic paraventricular nucleus and arcuate nucleus of type 2 diabetic rats. Toxicology and Applied Pharmacology 2022. [DOI: 10.1016/j.taap.2022.115893] [Reference Citation Analysis]
61 Lundqvist MH, Almby K, Abrahamsson N, Eriksson JW. Is the Brain a Key Player in Glucose Regulation and Development of Type 2 Diabetes? Front Physiol 2019;10:457. [PMID: 31133864 DOI: 10.3389/fphys.2019.00457] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 4.3] [Reference Citation Analysis]
62 Dong M, Gao C, Jia Y, Xu W, Liu Y, Wen X, Liu Q, Lin H, Li H. Temporal specificity of IL-6 knockout in enhancing the thermogenic capability of brown adipose tissue. J Physiol Biochem 2022. [PMID: 35349101 DOI: 10.1007/s13105-021-00847-4] [Reference Citation Analysis]
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