BPG is committed to discovery and dissemination of knowledge
Cited by in F6Publishing
For: Jacobson KA. New paradigms in GPCR drug discovery. Biochem Pharmacol 2015;98:541-55. [PMID: 26265138 DOI: 10.1016/j.bcp.2015.08.085] [Cited by in Crossref: 112] [Cited by in F6Publishing: 99] [Article Influence: 16.0] [Reference Citation Analysis]
Number Citing Articles
1 Bock A, Bermudez M. A panoramic view on GPCRs: the 1st Berlin Symposium for Interdisciplinary GPCR research. Naunyn Schmiedebergs Arch Pharmacol 2018;391:769-71. [PMID: 29781045 DOI: 10.1007/s00210-018-1513-5] [Reference Citation Analysis]
2 Gonchar M, Smutok O, Karkovska M, Stasyuk N, Gayda G. Yeast-Based Biosensors for Clinical Diagnostics and Food Control. In: Sibirny AA, editor. Biotechnology of Yeasts and Filamentous Fungi. Cham: Springer International Publishing; 2017. pp. 391-412. [DOI: 10.1007/978-3-319-58829-2_14] [Cited by in Crossref: 6] [Cited by in F6Publishing: 2] [Article Influence: 1.2] [Reference Citation Analysis]
3 Fulton MG, Loch MT, Cuoco CA, Rodriguez AL, Days E, Vinson PN, Kozek KA, Weaver CD, Blobaum AL, Conn PJ, Niswender CM, Lindsley CW. Challenges in the Discovery and Optimization of mGlu2/4 Heterodimer Positive Allosteric Modulators. Lett Drug Des Discov 2019;16:1387-94. [PMID: 32201485 DOI: 10.2174/1570180815666181017131349] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
4 Kim Y, Kim H, Lee J, Lee JK, Min SJ, Seong J, Rhim H, Tae J, Lee HJ, Choo H. Discovery of β-Arrestin Biased Ligands of 5-HT7R. J Med Chem 2018;61:7218-33. [PMID: 30028132 DOI: 10.1021/acs.jmedchem.8b00642] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 2.0] [Reference Citation Analysis]
5 Park SH, Berkamp S, Radoicic J, De Angelis AA, Opella SJ. Interaction of Monomeric Interleukin-8 with CXCR1 Mapped by Proton-Detected Fast MAS Solid-State NMR. Biophys J 2017;113:2695-705. [PMID: 29262362 DOI: 10.1016/j.bpj.2017.09.041] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 2.8] [Reference Citation Analysis]
6 Li Q, Ning X, An Y, Stanley BJ, Liang Y, Wang J, Zeng K, Fei F, Liu T, Sun H, Liu J, Zhao X, Zheng X. Reliable Analysis of the Interaction between Specific Ligands and Immobilized Beta-2-Adrenoceptor by Adsorption Energy Distribution. Anal Chem 2018;90:7903-11. [DOI: 10.1021/acs.analchem.8b00214] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.8] [Reference Citation Analysis]
7 Hothersall JD, Jones AY, Dafforn TR, Perrior T, Chapman KL. Releasing the technical 'shackles' on GPCR drug discovery: opportunities enabled by detergent-free polymer lipid particle (PoLiPa) purification. Drug Discov Today 2020:S1359-6446(20)30337-8. [PMID: 32835806 DOI: 10.1016/j.drudis.2020.08.006] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
8 Bassilana F, Nash M, Ludwig MG. Adhesion G protein-coupled receptors: opportunities for drug discovery. Nat Rev Drug Discov 2019;18:869-84. [PMID: 31462748 DOI: 10.1038/s41573-019-0039-y] [Cited by in Crossref: 20] [Cited by in F6Publishing: 21] [Article Influence: 6.7] [Reference Citation Analysis]
9 Lesiak L, Zhou X, Fang Y, Zhao J, Beck JR, Stains CI. Imaging GPCR internalization using near-infrared Nebraska red-based reagents. Org Biomol Chem 2020;18:2459-67. [PMID: 32167123 DOI: 10.1039/d0ob00043d] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
10 Kharche S, Joshi M, Chattopadhyay A, Sengupta D. Conformational plasticity and dynamic interactions of the N-terminal domain of the chemokine receptor CXCR1. PLoS Comput Biol 2021;17:e1008593. [PMID: 34014914 DOI: 10.1371/journal.pcbi.1008593] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
11 Sakuma K, Nakagawa H, Oikawa T, Noda M, Ikeda S. Effects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y 2 agonist, on cardiomyocytes in neonatal rats. Sci Rep 2017;7:6050. [PMID: 28729619 DOI: 10.1038/s41598-017-06481-9] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 1.6] [Reference Citation Analysis]
12 Kharche S, Joshi M, Sengupta D, Chattopadhyay A. Membrane-induced organization and dynamics of the N-terminal domain of chemokine receptor CXCR1: insights from atomistic simulations. Chem Phys Lipids 2018;210:142-8. [PMID: 28939366 DOI: 10.1016/j.chemphyslip.2017.09.003] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 1.4] [Reference Citation Analysis]
13 Leysen H, van Gastel J, Hendrickx JO, Santos-Otte P, Martin B, Maudsley S. G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes. Int J Mol Sci 2018;19:E2919. [PMID: 30261591 DOI: 10.3390/ijms19102919] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 3.5] [Reference Citation Analysis]
14 Stępnicki P, Kondej M, Kaczor AA. Current Concepts and Treatments of Schizophrenia. Molecules 2018;23:E2087. [PMID: 30127324 DOI: 10.3390/molecules23082087] [Cited by in Crossref: 72] [Cited by in F6Publishing: 46] [Article Influence: 18.0] [Reference Citation Analysis]
15 He X, Ni D, Lu S, Zhang J. Characteristics of Allosteric Proteins, Sites, and Modulators. In: Zhang J, Nussinov R, editors. Protein Allostery in Drug Discovery. Singapore: Springer; 2019. pp. 107-39. [DOI: 10.1007/978-981-13-8719-7_6] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 1.3] [Reference Citation Analysis]
16 Kumar GA, Chattopadhyay A. Statin-Induced Chronic Cholesterol Depletion Switches GPCR Endocytosis and Trafficking: Insights from the Serotonin1A Receptor. ACS Chem Neurosci 2020;11:453-65. [PMID: 31880914 DOI: 10.1021/acschemneuro.9b00659] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 9.0] [Reference Citation Analysis]
17 Mechaly AS, Tovar Bohórquez MO, Mechaly AE, Suku E, Pérez MR, Giorgetti A, Ortí G, Viñas J, Somoza GM. Evidence of Alternative Splicing as a Regulatory Mechanism for Kissr2 in Pejerrey Fish. Front Endocrinol (Lausanne) 2018;9:604. [PMID: 30386295 DOI: 10.3389/fendo.2018.00604] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
18 Sarkar P, Chattopadhyay A. Insights into cellular signaling from membrane dynamics. Arch Biochem Biophys 2021;701:108794. [PMID: 33571482 DOI: 10.1016/j.abb.2021.108794] [Reference Citation Analysis]
19 Ali DC, Naveed M, Gordon A, Majeed F, Saeed M, Ogbuke MI, Atif M, Zubair HM, Changxing L. β-Adrenergic receptor, an essential target in cardiovascular diseases. Heart Fail Rev 2020;25:343-54. [PMID: 31407140 DOI: 10.1007/s10741-019-09825-x] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 18.0] [Reference Citation Analysis]
20 Ranjan R, Pandey S, Shukla AK. Biased Opioid Receptor Ligands: Gain without Pain. Trends in Endocrinology & Metabolism 2017;28:247-9. [DOI: 10.1016/j.tem.2017.01.001] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 2.4] [Reference Citation Analysis]
21 Kumar GA, Sarkar P, Jafurulla M, Singh SP, Srinivas G, Pande G, Chattopadhyay A. Exploring Endocytosis and Intracellular Trafficking of the Human Serotonin 1A Receptor. Biochemistry 2019;58:2628-41. [DOI: 10.1021/acs.biochem.9b00033] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 3.3] [Reference Citation Analysis]
22 Di Pizio A, Waterloo LAW, Brox R, Löber S, Weikert D, Behrens M, Gmeiner P, Niv MY. Rational design of agonists for bitter taste receptor TAS2R14: from modeling to bench and back. Cell Mol Life Sci 2020;77:531-42. [PMID: 31236627 DOI: 10.1007/s00018-019-03194-2] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 4.7] [Reference Citation Analysis]
23 Gabr MT, Abdel-Raziq MS. Pharmacophore-based tailoring of biphenyl amide derivatives as selective 5-hydroxytryptamine 2B receptor antagonists. Medchemcomm 2018;9:1069-75. [PMID: 30108996 DOI: 10.1039/c8md00204e] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
24 Jafurulla M, Bandari S, Pucadyil TJ, Chattopadhyay A. Sphingolipids modulate the function of human serotonin1A receptors: Insights from sphingolipid-deficient cells. Biochim Biophys Acta Biomembr 2017;1859:598-604. [PMID: 27984018 DOI: 10.1016/j.bbamem.2016.10.016] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 2.0] [Reference Citation Analysis]
25 Noha SM, Schmidhammer H, Spetea M. Molecular Docking, Molecular Dynamics, and Structure-Activity Relationship Explorations of 14-Oxygenated N-Methylmorphinan-6-ones as Potent μ-Opioid Receptor Agonists. ACS Chem Neurosci 2017;8:1327-37. [PMID: 28125215 DOI: 10.1021/acschemneuro.6b00460] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 2.6] [Reference Citation Analysis]
26 Janero DR, Thakur GA. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target. Expert Opinion on Drug Discovery 2016;11:1223-37. [DOI: 10.1080/17460441.2016.1245289] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 2.5] [Reference Citation Analysis]
27 Sumitomo A, Siriwach R, Thumkeo D, Ito K, Nakagawa R, Tanaka N, Tanabe K, Watanabe A, Kishibe M, Ishida-yamamoto A, Honda T, Kabashima K, Aoki J, Narumiya S. LPA Induces Keratinocyte Differentiation and Promotes Skin Barrier Function through the LPAR1/LPAR5-RHO-ROCK-SRF Axis. Journal of Investigative Dermatology 2019;139:1010-22. [DOI: 10.1016/j.jid.2018.10.034] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 3.3] [Reference Citation Analysis]
28 Lindsley CW, Emmitte KA, Hopkins CR, Bridges TM, Gregory KJ, Niswender CM, Conn PJ. Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors. Chem Rev 2016;116:6707-41. [PMID: 26882314 DOI: 10.1021/acs.chemrev.5b00656] [Cited by in Crossref: 123] [Cited by in F6Publishing: 104] [Article Influence: 20.5] [Reference Citation Analysis]
29 Wang J, Bhattarai A, Ahmad WI, Farnan TS, John KP, Miao Y. Computer-aided GPCR drug discovery. GPCRs. Elsevier; 2020. pp. 283-93. [DOI: 10.1016/b978-0-12-816228-6.00015-5] [Cited by in Crossref: 2] [Article Influence: 1.0] [Reference Citation Analysis]
30 Chen CR, McLachlan SM, Hubbard PA, McNally R, Murali R, Rapoport B. Structure of a Thyrotropin Receptor Monoclonal Antibody Variable Region Provides Insight into Potential Mechanisms for its Inverse Agonist Activity. Thyroid 2018;28:933-40. [PMID: 29845889 DOI: 10.1089/thy.2018.0176] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
31 Bartuzi D, Wróbel TM, Kaczor AA, Matosiuk D. Tuning Down the Pain - An Overview of Allosteric Modulation of Opioid Receptors: Mechanisms of Modulation, Allosteric Sites, Modulator Syntheses. Curr Top Med Chem 2020;20:2852-65. [PMID: 32479245 DOI: 10.2174/1568026620666200601155451] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
32 Sarkar P, Chattopadhyay A. Solubilization of the serotonin 1A receptor monitored utilizing membrane dipole potential. Chemistry and Physics of Lipids 2017;209:54-60. [DOI: 10.1016/j.chemphyslip.2017.10.001] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.4] [Reference Citation Analysis]
33 Rao BD, Shrivastava S, Chattopadhyay A. Effect of local anesthetics on serotonin1A receptor function. Chemistry and Physics of Lipids 2016;201:41-9. [DOI: 10.1016/j.chemphyslip.2016.11.001] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
34 Waltenspühl Y, Ehrenmann J, Klenk C, Plückthun A. Engineering of Challenging G Protein-Coupled Receptors for Structure Determination and Biophysical Studies. Molecules 2021;26:1465. [PMID: 33800379 DOI: 10.3390/molecules26051465] [Reference Citation Analysis]
35 Karimi S, Ahmadi M, Goudarzi F, Ferdousi R. A computational model for GPCR-ligand interaction prediction. J Integr Bioinform 2020;18:155-65. [PMID: 34171942 DOI: 10.1515/jib-2019-0084] [Reference Citation Analysis]
36 Miao Y, McCammon JA. G-protein coupled receptors: advances in simulation and drug discovery. Curr Opin Struct Biol 2016;41:83-9. [PMID: 27344006 DOI: 10.1016/j.sbi.2016.06.008] [Cited by in Crossref: 56] [Cited by in F6Publishing: 55] [Article Influence: 9.3] [Reference Citation Analysis]
37 Jafurulla M, Nalli A, Chattopadhyay A. Membrane cholesterol oxidation in live cells enhances the function of serotonin 1A receptors. Chemistry and Physics of Lipids 2017;203:71-7. [DOI: 10.1016/j.chemphyslip.2017.01.005] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.8] [Reference Citation Analysis]
38 Fatakia SN, Sarkar P, Chattopadhyay A. Molecular evolution of a collage of cholesterol interaction motifs in transmembrane helix V of the serotonin1A receptor. Chem Phys Lipids 2020;232:104955. [PMID: 32846149 DOI: 10.1016/j.chemphyslip.2020.104955] [Reference Citation Analysis]
39 Doijen J, Van Loy T, Landuyt B, Luyten W, Schols D, Schoofs L. Advantages and shortcomings of cell-based electrical impedance measurements as a GPCR drug discovery tool. Biosens Bioelectron. 2019;137:33-44. [PMID: 31077988 DOI: 10.1016/j.bios.2019.04.041] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.7] [Reference Citation Analysis]
40 Kumar A, Sarkar P, Chattopadhyay A. Metabolic Depletion of Sphingolipids Reduces Cell Surface Population of the Human Serotonin1A Receptor due to Impaired Trafficking. ACS Chem Neurosci 2021;12:1189-96. [PMID: 33760584 DOI: 10.1021/acschemneuro.1c00017] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
41 Vass M, Kooistra AJ, Yang D, Stevens RC, Wang MW, de Graaf C. Chemical Diversity in the G Protein-Coupled Receptor Superfamily. Trends Pharmacol Sci 2018;39:494-512. [PMID: 29576399 DOI: 10.1016/j.tips.2018.02.004] [Cited by in Crossref: 44] [Cited by in F6Publishing: 37] [Article Influence: 11.0] [Reference Citation Analysis]
42 Eiden LE, Goosens KA, Jacobson KA, Leggio L, Zhang L. Peptide-Liganded G Protein-Coupled Receptors as Neurotherapeutics. ACS Pharmacol Transl Sci 2020;3:190-202. [PMID: 32296762 DOI: 10.1021/acsptsci.0c00017] [Cited by in Crossref: 2] [Article Influence: 1.0] [Reference Citation Analysis]
43 Garrido-Suárez BB, Garrido G, Piñeros O, Delgado-Hernández R. Mangiferin: Possible uses in the prevention and treatment of mixed osteoarthritic pain. Phytother Res 2020;34:505-25. [PMID: 31755173 DOI: 10.1002/ptr.6546] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
44 Daugvilaite V, Madsen CM, Lückmann M, Echeverria CC, Sailer AW, Frimurer TM, Rosenkilde MM, Benned-Jensen T. Biased agonism and allosteric modulation of G protein-coupled receptor 183 - a 7TM receptor also known as Epstein-Barr virus-induced gene 2. Br J Pharmacol 2017;174:2031-42. [PMID: 28369721 DOI: 10.1111/bph.13801] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 1.4] [Reference Citation Analysis]
45 Sengupta D, Prasanna X, Mohole M, Chattopadhyay A. Exploring GPCR–Lipid Interactions by Molecular Dynamics Simulations: Excitements, Challenges, and the Way Forward. J Phys Chem B 2018;122:5727-37. [DOI: 10.1021/acs.jpcb.8b01657] [Cited by in Crossref: 47] [Cited by in F6Publishing: 41] [Article Influence: 11.8] [Reference Citation Analysis]
46 Jafurulla M, Chattopadhyay A. Structural Stringency of Cholesterol for Membrane Protein Function Utilizing Stereoisomers as Novel Tools: A Review. In: Gelissen IC, Brown AJ, editors. Cholesterol Homeostasis. New York: Springer; 2017. pp. 21-39. [DOI: 10.1007/978-1-4939-6875-6_3] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
47 Johnstone S, Albert JS. Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective. Bioorg Med Chem Lett 2017;27:2239-58. [PMID: 28408223 DOI: 10.1016/j.bmcl.2017.03.084] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 2.8] [Reference Citation Analysis]
48 Yeliseev A, Iyer MR, Joseph TT, Coffey NJ, Cinar R, Zoubak L, Kunos G, Gawrisch K. Cholesterol as a modulator of cannabinoid receptor CB2 signaling. Sci Rep 2021;11:3706. [PMID: 33580091 DOI: 10.1038/s41598-021-83245-6] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
49 Xu Y, Sromek AW, Neumeyer JL. Identification of fluorinated (R)-(−)-aporphine derivatives as potent and selective ligands at serotonin 5-HT2C receptor. Bioorganic & Medicinal Chemistry Letters 2019;29:230-3. [DOI: 10.1016/j.bmcl.2018.11.050] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
50 Sengupta D, Kumar GA, Chattopadhyay A. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization. In: Herrick-davis K, Milligan G, Di Giovanni G, editors. G-Protein-Coupled Receptor Dimers. Cham: Springer International Publishing; 2017. pp. 415-29. [DOI: 10.1007/978-3-319-60174-8_16] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.6] [Reference Citation Analysis]
51 Zhang Y, Wang H, Zhu G, Qian A, Chen W. F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NFκB signaling pathways. Int J Biol Sci 2020;16:1629-39. [PMID: 32226307 DOI: 10.7150/ijbs.41867] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
52 Liu X, Zhao L, Wang Y, Zhou J, Wang D, Zhang Y, Zhang X, Wang Z, Yang D, Mou L, Wang R. MEL-N16: A Series of Novel Endomorphin Analogs with Good Analgesic Activity and a Favorable Side Effect Profile. ACS Chem Neurosci 2017;8:2180-93. [PMID: 28732166 DOI: 10.1021/acschemneuro.7b00097] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 2.0] [Reference Citation Analysis]
53 Kricker JA, Page CP, Gardarsson FR, Baldursson O, Gudjonsson T, Parnham MJ. Nonantimicrobial Actions of Macrolides: Overview and Perspectives for Future Development. Pharmacol Rev 2021;73:233-62. [PMID: 34716226 DOI: 10.1124/pharmrev.121.000300] [Reference Citation Analysis]
54 Schneider P, Schneider G. De-orphaning the marine natural product (±)-marinopyrrole A by computational target prediction and biochemical validation. Chem Commun 2017;53:2272-4. [DOI: 10.1039/c6cc09693j] [Cited by in Crossref: 20] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
55 Chakraborty H, Jafurulla M, Clayton AHA, Chattopadhyay A. Exploring oligomeric state of the serotonin 1A receptor utilizing photobleaching image correlation spectroscopy: implications for receptor function. Faraday Discuss 2018;207:409-21. [DOI: 10.1039/c7fd00192d] [Cited by in Crossref: 13] [Cited by in F6Publishing: 3] [Article Influence: 3.3] [Reference Citation Analysis]
56 Heifetz A, Aldeghi M, Chudyk EI, Fedorov DG, Bodkin MJ, Biggin PC. Using the fragment molecular orbital method to investigate agonist-orexin-2 receptor interactions. Biochem Soc Trans 2016;44:574-81. [PMID: 27068972 DOI: 10.1042/BST20150250] [Cited by in Crossref: 22] [Cited by in F6Publishing: 8] [Article Influence: 3.7] [Reference Citation Analysis]
57 Pal S, Aute R, Sarkar P, Bose S, Deshmukh MV, Chattopadhyay A. Constrained dynamics of the sole tryptophan in the third intracellular loop of the serotonin1A receptor. Biophys Chem 2018;240:34-41. [PMID: 29885563 DOI: 10.1016/j.bpc.2018.05.008] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 3.0] [Reference Citation Analysis]
58 [DOI: 10.1101/2020.01.11.902809] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
59 Palkeeva M, Studneva I, Molokoedov A, Serebryakova L, Veselova O, Ovchinnikov M, Sidorova M, Pisarenko O. Galanin/GalR1-3 system: A promising therapeutic target for myocardial ischemia/reperfusion injury. Biomed Pharmacother 2019;109:1556-62. [PMID: 30551408 DOI: 10.1016/j.biopha.2018.09.182] [Cited by in Crossref: 9] [Cited by in F6Publishing: 5] [Article Influence: 2.3] [Reference Citation Analysis]
60 Jafurulla M, Aditya Kumar G, Rao BD, Chattopadhyay A. A Critical Analysis of Molecular Mechanisms Underlying Membrane Cholesterol Sensitivity of GPCRs. Adv Exp Med Biol 2019;1115:21-52. [PMID: 30649754 DOI: 10.1007/978-3-030-04278-3_2] [Cited by in Crossref: 23] [Cited by in F6Publishing: 19] [Article Influence: 7.7] [Reference Citation Analysis]
61 Zhang Y, Zhang H, Ghosh D, Williams RO 3rd. Just how prevalent are peptide therapeutic products? A critical review. Int J Pharm 2020;587:119491. [PMID: 32622810 DOI: 10.1016/j.ijpharm.2020.119491] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 5.0] [Reference Citation Analysis]
62 De Francesco EM, Sotgia F, Clarke RB, Lisanti MP, Maggiolini M. G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts. Int J Mol Sci 2017;18:E2713. [PMID: 29240722 DOI: 10.3390/ijms18122713] [Cited by in Crossref: 16] [Cited by in F6Publishing: 12] [Article Influence: 3.2] [Reference Citation Analysis]
63 Rao BD, Sarkar P, Chattopadhyay A. Selectivity in agonist and antagonist binding to Serotonin1A receptors via G-protein coupling. Biochim Biophys Acta Biomembr 2020;1862:183265. [PMID: 32156647 DOI: 10.1016/j.bbamem.2020.183265] [Reference Citation Analysis]
64 Serebryakova L, Pal’keeva M, Studneva I, Molokoedov A, Veselova O, Ovchinnikov M, Gataulin R, Sidorova M, Pisarenko O. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides 2019;111:127-31. [DOI: 10.1016/j.peptides.2018.05.001] [Cited by in Crossref: 4] [Cited by in F6Publishing: 1] [Article Influence: 1.3] [Reference Citation Analysis]
65 Mårtensson J, Holdfeldt A, Sundqvist M, Gabl M, Kenakin TP, Björkman L, Forsman H, Dahlgren C. Neutrophil priming that turns natural FFA2R agonists into potent activators of the superoxide generating NADPH‐oxidase. J Leukoc Biol 2018;104:1117-32. [DOI: 10.1002/jlb.2a0318-130rr] [Cited by in Crossref: 19] [Cited by in F6Publishing: 9] [Article Influence: 4.8] [Reference Citation Analysis]
66 Button AL, Hiss JA, Schneider P, Schneider G. Scoring of de novo Designed Chemical Entities by Macromolecular Target Prediction. Mol Inform 2017;36. [PMID: 27643811 DOI: 10.1002/minf.201600110] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
67 Antunes G, Simoes de Souza FM. Olfactory receptor signaling. G Protein-Coupled Receptors - Signaling, Trafficking and Regulation. Elsevier; 2016. pp. 127-45. [DOI: 10.1016/bs.mcb.2015.11.003] [Cited by in Crossref: 22] [Cited by in F6Publishing: 19] [Article Influence: 3.7] [Reference Citation Analysis]
68 Lamichhane R, Liu JJ, White KL, Katritch V, Stevens RC, Wüthrich K, Millar DP. Biased Signaling of the G-Protein-Coupled Receptor β2AR Is Governed by Conformational Exchange Kinetics. Structure 2020;28:371-377.e3. [PMID: 31978323 DOI: 10.1016/j.str.2020.01.001] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 7.5] [Reference Citation Analysis]
69 Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE. Trends in GPCR drug discovery: new agents, targets and indications. Nat Rev Drug Discov 2017;16:829-42. [PMID: 29075003 DOI: 10.1038/nrd.2017.178] [Cited by in Crossref: 875] [Cited by in F6Publishing: 780] [Article Influence: 175.0] [Reference Citation Analysis]
70 De Silva SF, Alcorn J. Flaxseed Lignans as Important Dietary Polyphenols for Cancer Prevention and Treatment: Chemistry, Pharmacokinetics, and Molecular Targets. Pharmaceuticals (Basel) 2019;12:E68. [PMID: 31060335 DOI: 10.3390/ph12020068] [Cited by in Crossref: 21] [Cited by in F6Publishing: 18] [Article Influence: 7.0] [Reference Citation Analysis]
71 Peng Y, Zhao S, Wu Y, Cao H, Xu Y, Liu X, Shui W, Cheng J, Zhao S, Shen L, Ma J, Quinn RJ, Stevens RC, Zhong G, Liu ZJ. Identification of natural products as novel ligands for the human 5-HT2C receptor. Biophys Rep 2018;4:50-61. [PMID: 29577069 DOI: 10.1007/s41048-018-0047-1] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 3.3] [Reference Citation Analysis]
72 Kuroda Y, Nonaka M, Kamikubo Y, Ogawa H, Murayama T, Kurebayashi N, Sakairi H, Miyano K, Komatsu A, Dodo T, Nakano-Ito K, Yamaguchi K, Sakurai T, Iseki M, Hayashida M, Uezono Y. Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors. Biomed Pharmacother 2021;141:111800. [PMID: 34175819 DOI: 10.1016/j.biopha.2021.111800] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
73 Kamato D, Mitra P, Davis F, Osman N, Chaplin R, Cabot PJ, Afroz R, Thomas W, Zheng W, Kaur H, Brimble M, Little PJ. Gaq proteins: molecular pharmacology and therapeutic potential. Cell Mol Life Sci 2017;74:1379-90. [DOI: 10.1007/s00018-016-2405-9] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 4.0] [Reference Citation Analysis]
74 Sarkar P, Chattopadhyay A. Exploring membrane organization at varying spatiotemporal resolutions utilizing fluorescence-based approaches: implications in membrane biology. Phys Chem Chem Phys 2019;21:11554-63. [DOI: 10.1039/c9cp02087j] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 2.7] [Reference Citation Analysis]
75 Heifetz A, Storer RI, McMurray G, James T, Morao I, Aldeghi M, Bodkin MJ, Biggin PC. Application of an Integrated GPCR SAR-Modeling Platform To Explain the Activation Selectivity of Human 5-HT2C over 5-HT2B. ACS Chem Biol 2016;11:1372-82. [PMID: 26900768 DOI: 10.1021/acschembio.5b01045] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 1.8] [Reference Citation Analysis]
76 Kaur H, Carvalho J, Looso M, Singh P, Chennupati R, Preussner J, Günther S, Albarrán-Juárez J, Tischner D, Classen S, Offermanns S, Wettschureck N. Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system. Nat Commun 2017;8:15700. [PMID: 28621310 DOI: 10.1038/ncomms15700] [Cited by in Crossref: 47] [Cited by in F6Publishing: 41] [Article Influence: 9.4] [Reference Citation Analysis]
77 Di Pizio A, Behrens M, Krautwurst D. Beyond the Flavour: The Potential Druggability of Chemosensory G Protein-Coupled Receptors. Int J Mol Sci 2019;20:E1402. [PMID: 30897734 DOI: 10.3390/ijms20061402] [Cited by in Crossref: 29] [Cited by in F6Publishing: 24] [Article Influence: 9.7] [Reference Citation Analysis]
78 Kumar GA, Chattopadhyay A. Membrane cholesterol regulates endocytosis and trafficking of the serotonin1A receptor: Insights from acute cholesterol depletion. Biochim Biophys Acta Mol Cell Biol Lipids 2021;1866:158882. [PMID: 33429076 DOI: 10.1016/j.bbalip.2021.158882] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 3.0] [Reference Citation Analysis]
79 Bradley EC, Cunningham RL, Wilde C, Morgan RK, Klug EA, Letcher SM, Schöneberg T, Monk KR, Liebscher I, Petersen SC. In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development. Ann N Y Acad Sci 2019;1456:44-63. [PMID: 31529518 DOI: 10.1111/nyas.14233] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 2.7] [Reference Citation Analysis]
80 Lu S, Zhang J. Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug–Target Interactions. J Med Chem 2019;62:24-45. [DOI: 10.1021/acs.jmedchem.7b01844] [Cited by in Crossref: 66] [Cited by in F6Publishing: 60] [Article Influence: 16.5] [Reference Citation Analysis]
81 Ballante F, Kooistra AJ, Kampen S, de Graaf C, Carlsson J. Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You? Pharmacol Rev 2021;73:527-65. [PMID: 34907092 DOI: 10.1124/pharmrev.120.000246] [Reference Citation Analysis]
82 Heifetz A, Chudyk EI, Gleave L, Aldeghi M, Cherezov V, Fedorov DG, Biggin PC, Bodkin MJ. The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR–Ligand Interactions. J Chem Inf Model 2016;56:159-72. [DOI: 10.1021/acs.jcim.5b00644] [Cited by in Crossref: 71] [Cited by in F6Publishing: 63] [Article Influence: 10.1] [Reference Citation Analysis]
83 Haak AJ, Ducharme MT, Diaz Espinosa AM, Tschumperlin DJ. Targeting GPCR Signaling for Idiopathic Pulmonary Fibrosis Therapies. Trends Pharmacol Sci 2020;41:172-82. [PMID: 32008852 DOI: 10.1016/j.tips.2019.12.008] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 6.0] [Reference Citation Analysis]
84 Webling K, Runesson J, Lang A, Saar I, Kofler B, Langel Ü. Ala 5 -galanin (2–11) is a GAL 2 R specific galanin analogue. Neuropeptides 2016;60:75-82. [DOI: 10.1016/j.npep.2016.08.008] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 1.7] [Reference Citation Analysis]
85 Prasanna X, Jafurulla M, Sengupta D, Chattopadhyay A. The ganglioside GM1 interacts with the serotonin 1A receptor via the sphingolipid binding domain. Biochimica et Biophysica Acta (BBA) - Biomembranes 2016;1858:2818-26. [DOI: 10.1016/j.bbamem.2016.08.009] [Cited by in Crossref: 34] [Cited by in F6Publishing: 29] [Article Influence: 5.7] [Reference Citation Analysis]
86 Heifetz A, James T, Morao I, Bodkin MJ, Biggin PC. Guiding lead optimization with GPCR structure modeling and molecular dynamics. Current Opinion in Pharmacology 2016;30:14-21. [DOI: 10.1016/j.coph.2016.06.004] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 3.3] [Reference Citation Analysis]
87 Diaz C, Angelloz-Nicoud P, Pihan E. Modeling and Deorphanization of Orphan GPCRs. Methods Mol Biol 2018;1705:413-29. [PMID: 29188576 DOI: 10.1007/978-1-4939-7465-8_21] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
88 Bohn LM, Aubé J. Seeking (and Finding) Biased Ligands of the Kappa Opioid Receptor. ACS Med Chem Lett 2017;8:694-700. [PMID: 28740600 DOI: 10.1021/acsmedchemlett.7b00224] [Cited by in Crossref: 18] [Cited by in F6Publishing: 16] [Article Influence: 3.6] [Reference Citation Analysis]
89 Rao BD, Sarkar P, Chattopadhyay A. Effect of tertiary amine local anesthetics on G protein-coupled receptor lateral diffusion and actin cytoskeletal reorganization. Biochim Biophys Acta Biomembr 2021;1863:183547. [PMID: 33417968 DOI: 10.1016/j.bbamem.2020.183547] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
90 Pal S, Chattopadhyay A. Extramembranous Regions in G Protein-Coupled Receptors: Cinderella in Receptor Biology? J Membrane Biol 2019;252:483-97. [DOI: 10.1007/s00232-019-00092-3] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 4.7] [Reference Citation Analysis]
91 Wang J, Bian C, Wang Y, Shen Q, Bao B, Fan J, Zuo A, Wu W, Guo R. Syntheses and bioactivities of songorine derivatives as novel G protein-coupled receptor antagonists. Bioorg Med Chem 2019;27:1903-10. [PMID: 30926314 DOI: 10.1016/j.bmc.2019.03.045] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.7] [Reference Citation Analysis]
92 Barrantes FJ. Cholesterol and nicotinic acetylcholine receptor: An intimate nanometer-scale spatial relationship spanning the billion year time-scale. BSI 2016;5:S67-86. [DOI: 10.3233/bsi-160158] [Cited by in Crossref: 1] [Article Influence: 0.2] [Reference Citation Analysis]
93 Bhattarai A, Wang J, Miao Y. Retrospective ensemble docking of allosteric modulators in an adenosine G-protein-coupled receptor. Biochim Biophys Acta Gen Subj 2020;1864:129615. [PMID: 32298791 DOI: 10.1016/j.bbagen.2020.129615] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 2.5] [Reference Citation Analysis]
94 Sengupta D, Sonar K, Joshi M. Characterizing clinically relevant natural variants of GPCRs using computational approaches. G Protein-Coupled Receptors Part A. Elsevier; 2017. pp. 187-204. [DOI: 10.1016/bs.mcb.2017.07.013] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 1.2] [Reference Citation Analysis]
95 Matera C, Bono F, Pelucchi S, Collo G, Bontempi L, Gotti C, Zoli M, De Amici M, Missale C, Fiorentini C, Dallanoce C. The novel hybrid agonist HyNDA-1 targets the D3R-nAChR heteromeric complex in dopaminergic neurons. Biochem Pharmacol 2019;163:154-68. [PMID: 30772268 DOI: 10.1016/j.bcp.2019.02.019] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.7] [Reference Citation Analysis]
96 Shrivastava S, Jafurulla M, Tiwari S, Chattopadhyay A. Identification of Sphingolipid-binding Motif in G Protein-coupled Receptors. In: Chattopadhyay K, Basu SC, editors. Biochemical and Biophysical Roles of Cell Surface Molecules. Singapore: Springer; 2018. pp. 141-9. [DOI: 10.1007/978-981-13-3065-0_10] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 2.3] [Reference Citation Analysis]
97 Wheeler NA, Fuss B. Extracellular cues influencing oligodendrocyte differentiation and (re)myelination. Exp Neurol 2016;283:512-30. [PMID: 27016069 DOI: 10.1016/j.expneurol.2016.03.019] [Cited by in Crossref: 38] [Cited by in F6Publishing: 39] [Article Influence: 6.3] [Reference Citation Analysis]
98 Cooper A, Singh S, Hook S, Tyndall JDA, Vernall AJ. Chemical Tools for Studying Lipid-Binding Class A G Protein-Coupled Receptors. Pharmacol Rev 2017;69:316-53. [PMID: 28655732 DOI: 10.1124/pr.116.013243] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 2.2] [Reference Citation Analysis]
99 Xu M, Hong R, Zhang X, Zou H, Zhang Y, Hou Z, Wang L. CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model. Oncotarget 2017;8:108418-29. [PMID: 29312540 DOI: 10.18632/oncotarget.22664] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
100 Cole KLH, Early JJ, Lyons DA. Drug discovery for remyelination and treatment of MS. Glia 2017;65:1565-89. [PMID: 28618073 DOI: 10.1002/glia.23166] [Cited by in Crossref: 29] [Cited by in F6Publishing: 27] [Article Influence: 5.8] [Reference Citation Analysis]
101 Shrivastava S, Sarkar P, Preira P, Salomé L, Chattopadhyay A. Role of Actin Cytoskeleton in Dynamics and Function of the Serotonin1A Receptor. Biophys J 2020;118:944-56. [PMID: 31606121 DOI: 10.1016/j.bpj.2019.08.034] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
102 Alfonzo-Méndez MA, Alcántara-Hernández R, García-Sáinz JA. Novel Structural Approaches to Study GPCR Regulation. Int J Mol Sci 2016;18:E27. [PMID: 28025563 DOI: 10.3390/ijms18010027] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 2.0] [Reference Citation Analysis]