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For: Warfield KL, Plummer EM, Sayce AC, Alonzi DS, Tang W, Tyrrell BE, Hill ML, Caputo AT, Killingbeck SS, Beatty PR, Harris E, Iwaki R, Kinami K, Ide D, Kiappes JL, Kato A, Buck MD, King K, Eddy W, Khaliq M, Sampath A, Treston AM, Dwek RA, Enterlein SG, Miller JL, Zitzmann N, Ramstedt U, Shresta S. Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4. Antiviral Res 2016;129:93-8. [PMID: 26946111 DOI: 10.1016/j.antiviral.2016.03.001] [Cited by in Crossref: 31] [Cited by in F6Publishing: 30] [Article Influence: 5.2] [Reference Citation Analysis]
Number Citing Articles
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2 Tyrrell BE, Sayce AC, Warfield KL, Miller JL, Zitzmann N. Iminosugars: Promising therapeutics for influenza infection. Crit Rev Microbiol 2017;43:521-45. [PMID: 27931136 DOI: 10.1080/1040841X.2016.1242868] [Cited by in Crossref: 24] [Cited by in F6Publishing: 11] [Article Influence: 4.0] [Reference Citation Analysis]
3 Troost B, Smit JM. Recent advances in antiviral drug development towards dengue virus. Curr Opin Virol 2020;43:9-21. [PMID: 32795907 DOI: 10.1016/j.coviro.2020.07.009] [Cited by in Crossref: 9] [Cited by in F6Publishing: 11] [Article Influence: 4.5] [Reference Citation Analysis]
4 Mohd Abd Razak MR, Mohmad Misnan N, Md Jelas NH, Norahmad NA, Muhammad A, Ho TCD, Jusoh B, Sastu UR, Zainol M, Wasiman MI, Muhammad H, Thayan R, Syed Mohamed AF. The effect of freeze-dried Carica papaya leaf juice treatment on NS1 and viremia levels in dengue fever mice model. BMC Complement Altern Med 2018;18:320. [PMID: 30518360 DOI: 10.1186/s12906-018-2390-7] [Cited by in Crossref: 8] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
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6 Lai JH, Lin YL, Hsieh SL. Pharmacological intervention for dengue virus infection. Biochem Pharmacol 2017;129:14-25. [PMID: 28104437 DOI: 10.1016/j.bcp.2017.01.005] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 3.8] [Reference Citation Analysis]
7 Sarkar C, Quispe C, Islam MT, Jamaddar S, Akram M, Munior N, Martorell M, Kumar M, Sharifi-Rad J, Cruz-Martins N. Plant-derived alkaloids acting on dengue virus and their vectors: from chemistry to pharmacology. Future Microbiol 2021. [PMID: 34913374 DOI: 10.2217/fmb-2021-0002] [Reference Citation Analysis]
8 Alonzi DS, Scott KA, Dwek RA, Zitzmann N. Iminosugar antivirals: the therapeutic sweet spot. Biochem Soc Trans 2017;45:571-82. [PMID: 28408497 DOI: 10.1042/BST20160182] [Cited by in Crossref: 43] [Cited by in F6Publishing: 23] [Article Influence: 8.6] [Reference Citation Analysis]
9 Warfield KL, Alonzi DS, Hill JC, Caputo AT, Roversi P, Kiappes JL, Sheets N, Duchars M, Dwek RA, Biggins J, Barnard D, Shresta S, Treston AM, Zitzmann N. Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections. J Med Chem 2020;63:4205-14. [DOI: 10.1021/acs.jmedchem.0c00067] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 4.0] [Reference Citation Analysis]
10 Warfield KL, Warren TK, Qiu X, Wells J, Mire CE, Geisbert JB, Stuthman KS, Garza NL, Van Tongeren SA, Shurtleff AC, Agans KN, Wong G, Callahan MV, Geisbert TW, Klose B, Ramstedt U, Treston AM. Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo. Antiviral Res 2017;138:22-31. [PMID: 27908828 DOI: 10.1016/j.antiviral.2016.11.019] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 1.8] [Reference Citation Analysis]
11 Karade SS, Hill ML, Kiappes JL, Manne R, Aakula B, Zitzmann N, Warfield KL, Treston AM, Mariuzza RA. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. J Med Chem 2021;64:18010-24. [PMID: 34870992 DOI: 10.1021/acs.jmedchem.1c01377] [Reference Citation Analysis]
12 Low JG, Gatsinga R, Vasudevan SG, Sampath A. Dengue Antiviral Development: A Continuing Journey. Adv Exp Med Biol 2018;1062:319-32. [PMID: 29845542 DOI: 10.1007/978-981-10-8727-1_22] [Cited by in Crossref: 9] [Cited by in F6Publishing: 11] [Article Influence: 2.3] [Reference Citation Analysis]
13 Marti L, Lia A, Reca IB, Roversi P, Santino A, Zitzmann N. In Planta Preliminary Screening of ER Glycoprotein Folding Quality Control (ERQC) Modulators. Int J Mol Sci 2018;19:E2135. [PMID: 30041423 DOI: 10.3390/ijms19072135] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
14 Sayce AC, Martinez FO, Tyrrell BE, Perera N, Hill ML, Dwek RA, Miller JL, Zitzmann N. Pathogen-induced inflammation is attenuated by the iminosugar MON-DNJ via modulation of the unfolded protein response. Immunology 2021. [PMID: 34287854 DOI: 10.1111/imm.13393] [Reference Citation Analysis]
15 Lu TT, Shimadate Y, Cheng B, Kanekiyo U, Kato A, Wang JZ, Li YX, Jia YM, Fleet GWJ, Yu CY. Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives. Eur J Med Chem 2021;224:113716. [PMID: 34340042 DOI: 10.1016/j.ejmech.2021.113716] [Reference Citation Analysis]
16 Miller JL, Spiro SG, Dowall SD, Taylor I, Rule A, Alonzi DS, Sayce AC, Wright E, Bentley EM, Thom R, Hall G, Dwek RA, Hewson R, Zitzmann N. Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model. PLoS One 2016;11:e0167018. [PMID: 27880800 DOI: 10.1371/journal.pone.0167018] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.5] [Reference Citation Analysis]
17 Miller JL, Tyrrell BE, Zitzmann N. Mechanisms of Antiviral Activity of Iminosugars Against Dengue Virus. Adv Exp Med Biol 2018;1062:277-301. [PMID: 29845540 DOI: 10.1007/978-981-10-8727-1_20] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 3.3] [Reference Citation Analysis]
18 Evans DeWald L, Starr C, Butters T, Treston A, Warfield KL. Iminosugars: A host-targeted approach to combat Flaviviridae infections. Antiviral Res 2020;184:104881. [PMID: 32768411 DOI: 10.1016/j.antiviral.2020.104881] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
19 Caputo AT, Alonzi DS, Kiappes JL, Struwe WB, Cross A, Basu S, Darlot B, Roversi P, Zitzmann N. Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidase II. Adv Exp Med Biol 2018;1062:265-76. [PMID: 29845539 DOI: 10.1007/978-981-10-8727-1_19] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 1.5] [Reference Citation Analysis]
20 Ma J, Zhang X, Soloveva V, Warren T, Guo F, Wu S, Lu H, Guo J, Su Q, Shen H, Solon E, Comunale MA, Mehta A, Guo JT, Bavari S, Du Y, Block TM, Chang J. Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo. Antiviral Res 2018;150:112-22. [PMID: 29253498 DOI: 10.1016/j.antiviral.2017.12.008] [Cited by in Crossref: 18] [Cited by in F6Publishing: 15] [Article Influence: 3.6] [Reference Citation Analysis]
21 Gale TV, Horton TM, Hoffmann AR, Branco LM, Garry RF. Host Proteins Identified in Extracellular Viral Particles as Targets for Broad-Spectrum Antiviral Inhibitors. J Proteome Res 2019;18:7-17. [PMID: 30351952 DOI: 10.1021/acs.jproteome.8b00204] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
22 Dwek RA, Bell JI, Feldmann M, Zitzmann N. Host-targeting oral antiviral drugs to prevent pandemics. The Lancet 2022. [DOI: 10.1016/s0140-6736(22)00454-8] [Reference Citation Analysis]
23 Kiappes JL, Hill ML, Alonzi DS, Miller JL, Iwaki R, Sayce AC, Caputo AT, Kato A, Zitzmann N. ToP-DNJ, a Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II Exhibiting Antiflaviviral Activity. ACS Chem Biol 2018;13:60-5. [PMID: 29161006 DOI: 10.1021/acschembio.7b00870] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 5.0] [Reference Citation Analysis]
24 Karade SS, Kolesnikov A, Treston AM, Mariuzza RA. Identification of Endoplasmic Reticulum α-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design. Biochemistry 2022. [PMID: 35476408 DOI: 10.1021/acs.biochem.2c00092] [Reference Citation Analysis]
25 Yap SSL, Nguyen-Khuong T, Rudd PM, Alonso S. Dengue Virus Glycosylation: What Do We Know? Front Microbiol 2017;8:1415. [PMID: 28791003 DOI: 10.3389/fmicb.2017.01415] [Cited by in Crossref: 32] [Cited by in F6Publishing: 28] [Article Influence: 6.4] [Reference Citation Analysis]
26 Sung C, Wei Y, Watanabe S, Lee HS, Khoo YM, Fan L, Rathore AP, Chan KW, Choy MM, Kamaraj US, Sessions OM, Aw P, de Sessions PF, Lee B, Connolly JE, Hibberd ML, Vijaykrishna D, Wijaya L, Ooi EE, Low JG, Vasudevan SG. Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients. PLoS Negl Trop Dis 2016;10:e0004851. [PMID: 27509020 DOI: 10.1371/journal.pntd.0004851] [Cited by in Crossref: 33] [Cited by in F6Publishing: 32] [Article Influence: 5.5] [Reference Citation Analysis]
27 Anasir MI, Ramanathan B, Poh CL. Structure-Based Design of Antivirals against Envelope Glycoprotein of Dengue Virus. Viruses 2020;12:E367. [PMID: 32225021 DOI: 10.3390/v12040367] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 4.5] [Reference Citation Analysis]
28 Caputo AT, Alonzi DS, Marti L, Reca IB, Kiappes JL, Struwe WB, Cross A, Basu S, Lowe ED, Darlot B, Santino A, Roversi P, Zitzmann N. Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals. Proc Natl Acad Sci U S A 2016;113:E4630-8. [PMID: 27462106 DOI: 10.1073/pnas.1604463113] [Cited by in Crossref: 38] [Cited by in F6Publishing: 30] [Article Influence: 6.3] [Reference Citation Analysis]
29 Misumi I, Li Z, Sun L, Das A, Shiota T, Cullen J, Zhang Q, Whitmire JK, Lemon SM. Iminosugar glucosidase inhibitors reduce hepatic inflammation in HAV-infected Ifnar1-/- mice. J Virol 2021:JVI. [PMID: 33692213 DOI: 10.1128/JVI.00058-21] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
30 Su X, Wang Q, Wen Y, Jiang S, Lu L. Protein- and Peptide-Based Virus Inactivators: Inactivating Viruses Before Their Entry Into Cells. Front Microbiol 2020;11:1063. [PMID: 32523582 DOI: 10.3389/fmicb.2020.01063] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 3.5] [Reference Citation Analysis]
31 Gorantla JN, Maniganda S, Pengthaisong S, Ngiwsara L, Sawangareetrakul P, Chokchaisiri S, Kittakoop P, Svasti J, Ketudat Cairns JR. Chemoenzymatic and Protecting-Group-Free Synthesis of 1,4-Substituted 1,2,3-Triazole-α-d-glucosides with Potent Inhibitory Activity toward Lysosomal α-Glucosidase. ACS Omega 2021;6:25710-9. [PMID: 34632227 DOI: 10.1021/acsomega.1c03928] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
32 Darwish NT, Sekaran SD, Khor SM. Point-of-care tests: A review of advances in the emerging diagnostic tools for dengue virus infection. Sensors and Actuators B: Chemical 2018;255:3316-31. [DOI: 10.1016/j.snb.2017.09.159] [Cited by in Crossref: 36] [Cited by in F6Publishing: 20] [Article Influence: 9.0] [Reference Citation Analysis]
33 Warfield KL, Schaaf KR, DeWald LE, Spurgers KB, Wang W, Stavale E, Mendenhall M, Shilts MH, Stockwell TB, Barnard DL, Ramstedt U, Das SR. Lack of selective resistance of influenza A virus in presence of host-targeted antiviral, UV-4B. Sci Rep 2019;9:7484. [PMID: 31097731 DOI: 10.1038/s41598-019-43030-y] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 4.0] [Reference Citation Analysis]
34 Franco EJ, Pires de Mello CP, Brown AN. Antiviral Evaluation of UV-4B and Interferon-Alpha Combination Regimens against Dengue Virus. Viruses 2021;13:771. [PMID: 33925551 DOI: 10.3390/v13050771] [Reference Citation Analysis]
35 Warfield KL, Barnard DL, Enterlein SG, Smee DF, Khaliq M, Sampath A, Callahan MV, Ramstedt U, Day CW. The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice. Viruses 2016;8:71. [PMID: 27072420 DOI: 10.3390/v8030071] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 2.7] [Reference Citation Analysis]