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For: Johnson PL, Molosh A, Fitz SD, Truitt WA, Shekhar A. Orexin, stress, and anxiety/panic states. Prog Brain Res 2012;198:133-61. [PMID: 22813973 DOI: 10.1016/B978-0-444-59489-1.00009-4] [Cited by in Crossref: 125] [Cited by in F6Publishing: 69] [Article Influence: 12.5] [Reference Citation Analysis]
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3 Gomes-de-Souza L, Costa-Ferreira W, Mendonça MM, Xavier CH, Crestani CC. Lateral hypothalamus involvement in control of stress response by bed nucleus of the stria terminalis endocannabinoid neurotransmission in male rats. Sci Rep 2021;11:16133. [PMID: 34373508 DOI: 10.1038/s41598-021-95401-z] [Reference Citation Analysis]
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5 Schmeichel BE, Herman MA, Roberto M, Koob GF. Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in Rats. Biol Psychiatry 2017;81:606-15. [PMID: 27567312 DOI: 10.1016/j.biopsych.2016.06.010] [Cited by in Crossref: 47] [Cited by in F6Publishing: 43] [Article Influence: 7.8] [Reference Citation Analysis]
6 Mahler SV, Smith RJ, Moorman DE, Sartor GC, Aston-Jones G. Multiple roles for orexin/hypocretin in addiction. Prog Brain Res 2012;198:79-121. [PMID: 22813971 DOI: 10.1016/B978-0-444-59489-1.00007-0] [Cited by in Crossref: 140] [Cited by in F6Publishing: 76] [Article Influence: 14.0] [Reference Citation Analysis]
7 Grafe LA, Eacret D, Dobkin J, Bhatnagar S. Reduced Orexin System Function Contributes to Resilience to Repeated Social Stress. eNeuro 2018;5:ENEURO. [PMID: 29662948 DOI: 10.1523/ENEURO.0273-17.2018] [Cited by in Crossref: 33] [Cited by in F6Publishing: 15] [Article Influence: 8.3] [Reference Citation Analysis]
8 Grafe LA, Geng E, Corbett B, Urban K, Bhatnagar S. Sex- and Stress-Dependent Effects on Dendritic Morphology and Spine Densities in Putative Orexin Neurons. Neuroscience 2019;418:266-78. [PMID: 31442567 DOI: 10.1016/j.neuroscience.2019.08.026] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.7] [Reference Citation Analysis]
9 Barretto-de-Souza L, Benini R, Reis-Silva LL, Crestani CC. Role of CRF1 and CRF2 receptors in the lateral hypothalamus in cardiovascular and anxiogenic responses evoked by restraint stress in rats: Evaluation of acute and chronic exposure. Neuropharmacology 2022;:109061. [PMID: 35452627 DOI: 10.1016/j.neuropharm.2022.109061] [Reference Citation Analysis]
10 Grafe LA, Bhatnagar S. The contribution of orexins to sex differences in the stress response. Brain Res 2020;1731:145893. [PMID: 30081036 DOI: 10.1016/j.brainres.2018.07.026] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 2.8] [Reference Citation Analysis]
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12 Grafe LA, Eacret D, Luz S, Gotter AL, Renger JJ, Winrow CJ, Bhatnagar S. Orexin 2 receptor regulation of the hypothalamic-pituitary-adrenal (HPA) response to acute and repeated stress. Neuroscience 2017;348:313-23. [PMID: 28257896 DOI: 10.1016/j.neuroscience.2017.02.038] [Cited by in Crossref: 28] [Cited by in F6Publishing: 26] [Article Influence: 5.6] [Reference Citation Analysis]
13 Li A, Nattie E. Orexin, cardio-respiratory function, and hypertension. Front Neurosci 2014;8:22. [PMID: 24574958 DOI: 10.3389/fnins.2014.00022] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
14 Han D, Shi Y, Han F. The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder. J Comp Neurol 2022;530:592-606. [PMID: 34387361 DOI: 10.1002/cne.25231] [Reference Citation Analysis]
15 Severs L, Vlemincx E, Ramirez J. The psychophysiology of the sigh: I: The sigh from the physiological perspective. Biological Psychology 2022. [DOI: 10.1016/j.biopsycho.2022.108313] [Reference Citation Analysis]
16 Johnson PL, Federici LM, Fitz SD, Renger JJ, Shireman B, Winrow CJ, Bonaventure P, Shekhar A. OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO2 -INDUCED PANIC-ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES. Depress Anxiety 2015;32:671-83. [PMID: 26332431 DOI: 10.1002/da.22403] [Cited by in Crossref: 45] [Cited by in F6Publishing: 39] [Article Influence: 6.4] [Reference Citation Analysis]
17 Deats SP, Adidharma W, Lonstein JS, Yan L. Attenuated orexinergic signaling underlies depression-like responses induced by daytime light deficiency. Neuroscience 2014;272:252-60. [PMID: 24813431 DOI: 10.1016/j.neuroscience.2014.04.069] [Cited by in Crossref: 33] [Cited by in F6Publishing: 29] [Article Influence: 4.1] [Reference Citation Analysis]
18 Stanojlovic M, Pallais JP, Lee MK, Kotz CM. Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson's disease. Mol Brain 2019;12:87. [PMID: 31666100 DOI: 10.1186/s13041-019-0514-8] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 2.0] [Reference Citation Analysis]
19 Schmeichel BE, Barbier E, Misra KK, Contet C, Schlosburg JE, Grigoriadis D, Williams JP, Karlsson C, Pitcairn C, Heilig M, Koob GF, Vendruscolo LF. Hypocretin receptor 2 antagonism dose-dependently reduces escalated heroin self-administration in rats. Neuropsychopharmacology 2015;40:1123-9. [PMID: 25367502 DOI: 10.1038/npp.2014.293] [Cited by in Crossref: 49] [Cited by in F6Publishing: 35] [Article Influence: 7.0] [Reference Citation Analysis]
20 Bonaventure P, Dugovic C, Shireman B, Preville C, Yun S, Lord B, Nepomuceno D, Wennerholm M, Lovenberg T, Carruthers N, Fitz SD, Shekhar A, Johnson PL. Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation. Front Pharmacol 2017;8:357. [PMID: 28649201 DOI: 10.3389/fphar.2017.00357] [Cited by in Crossref: 22] [Cited by in F6Publishing: 19] [Article Influence: 4.4] [Reference Citation Analysis]
21 Summers CH, Yaeger JDW, Staton CD, Arendt DH, Summers TR. Orexin/hypocretin receptor modulation of anxiolytic and antidepressive responses during social stress and decision-making: Potential for therapy. Brain Res 2020;1731:146085. [PMID: 30590027 DOI: 10.1016/j.brainres.2018.12.036] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 3.8] [Reference Citation Analysis]
22 Johnson PL, Federici LM, Shekhar A. Etiology, triggers and neurochemical circuits associated with unexpected, expected, and laboratory-induced panic attacks. Neurosci Biobehav Rev 2014;46 Pt 3:429-54. [PMID: 25130976 DOI: 10.1016/j.neubiorev.2014.07.027] [Cited by in Crossref: 29] [Cited by in F6Publishing: 25] [Article Influence: 3.6] [Reference Citation Analysis]
23 Leibold NK, van den Hove DL, Viechtbauer W, Buchanan GF, Goossens L, Lange I, Knuts I, Lesch KP, Steinbusch HW, Schruers KR. CO2 exposure as translational cross-species experimental model for panic. Transl Psychiatry 2016;6:e885. [PMID: 27598969 DOI: 10.1038/tp.2016.162] [Cited by in Crossref: 28] [Cited by in F6Publishing: 26] [Article Influence: 4.7] [Reference Citation Analysis]
24 Matzeu A, Martin-Fardon R. Cocaine-Seeking Behavior Induced by Orexin A Administration in the Posterior Paraventricular Nucleus of the Thalamus Is Not Long-Lasting: Neuroadaptation of the Orexin System During Cocaine Abstinence. Front Behav Neurosci 2021;15:620868. [PMID: 33708078 DOI: 10.3389/fnbeh.2021.620868] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
25 Pizza F, Magnani M, Indrio C, Plazzi G. The hypocretin system and psychiatric disorders. Curr Psychiatry Rep 2014;16:433. [PMID: 24363104 DOI: 10.1007/s11920-013-0433-9] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 2.4] [Reference Citation Analysis]
26 Schmeichel BE, Matzeu A, Koebel P, Vendruscolo LF, Sidhu H, Shahryari R, Kieffer BL, Koob GF, Martin-Fardon R, Contet C. Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats. Neuropsychopharmacology 2018;43:2373-82. [PMID: 29703996 DOI: 10.1038/s41386-018-0054-4] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 5.0] [Reference Citation Analysis]
27 Odegaard KE, Schaal VL, Clark AR, Koul S, Gowen A, Sankarasubramani J, Xiao P, Guda C, Lisco SJ, Yelamanchili SV, Pendyala G. Characterization of the intergenerational impact of in utero and postnatal oxycodone exposure. Transl Psychiatry 2020;10:329. [PMID: 32968044 DOI: 10.1038/s41398-020-01012-z] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
28 Richards A, Kanady JC, Neylan TC. Sleep disturbance in PTSD and other anxiety-related disorders: an updated review of clinical features, physiological characteristics, and psychological and neurobiological mechanisms. Neuropsychopharmacology 2020;45:55-73. [PMID: 31443103 DOI: 10.1038/s41386-019-0486-5] [Cited by in Crossref: 27] [Cited by in F6Publishing: 23] [Article Influence: 9.0] [Reference Citation Analysis]
29 Wilson MA, Grillo CA, Fadel JR, Reagan LP. Stress as a one-armed bandit: Differential effects of stress paradigms on the morphology, neurochemistry and behavior in the rodent amygdala. Neurobiol Stress 2015;1:195-208. [PMID: 26844236 DOI: 10.1016/j.ynstr.2015.06.001] [Cited by in Crossref: 45] [Cited by in F6Publishing: 37] [Article Influence: 6.4] [Reference Citation Analysis]
30 Ramirez JM. The integrative role of the sigh in psychology, physiology, pathology, and neurobiology. Prog Brain Res 2014;209:91-129. [PMID: 24746045 DOI: 10.1016/B978-0-444-63274-6.00006-0] [Cited by in Crossref: 63] [Cited by in F6Publishing: 29] [Article Influence: 9.0] [Reference Citation Analysis]
31 Collier AD, Min SS, Campbell SD, Roberts MY, Camidge K, Leibowitz SF. Maternal ethanol consumption before paternal fertilization: Stimulation of hypocretin neurogenesis and ethanol intake in zebrafish offspring. Prog Neuropsychopharmacol Biol Psychiatry 2020;96:109728. [PMID: 31394141 DOI: 10.1016/j.pnpbp.2019.109728] [Cited by in Crossref: 12] [Cited by in F6Publishing: 13] [Article Influence: 4.0] [Reference Citation Analysis]
32 Bayard S, Langenier MC, Dauvilliers Y. Effect of psychostimulants on impulsivity and risk taking in narcolepsy with cataplexy. Sleep 2013;36:1335-40. [PMID: 23997366 DOI: 10.5665/sleep.2958] [Cited by in Crossref: 19] [Cited by in F6Publishing: 13] [Article Influence: 2.1] [Reference Citation Analysis]
33 Nevárez N, de Lecea L. Recent advances in understanding the roles of hypocretin/orexin in arousal, affect, and motivation. F1000Res 2018;7:F1000 Faculty Rev-1421. [PMID: 30254737 DOI: 10.12688/f1000research.15097.1] [Cited by in Crossref: 23] [Cited by in F6Publishing: 18] [Article Influence: 5.8] [Reference Citation Analysis]
34 Merlo Pich E, Melotto S. Orexin 1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use. Front Neurosci 2014;8:26. [PMID: 24592206 DOI: 10.3389/fnins.2014.00026] [Cited by in Crossref: 30] [Cited by in F6Publishing: 31] [Article Influence: 3.8] [Reference Citation Analysis]
35 Chiu CN, Prober DA. Regulation of zebrafish sleep and arousal states: current and prospective approaches. Front Neural Circuits 2013;7:58. [PMID: 23576957 DOI: 10.3389/fncir.2013.00058] [Cited by in Crossref: 38] [Cited by in F6Publishing: 36] [Article Influence: 4.2] [Reference Citation Analysis]
36 Ikeno T, Yan L. A comparison of the orexin receptor distribution in the brain between diurnal Nile grass rats (Arvicanthis niloticus) and nocturnal mice (Mus musculus). Brain Res 2018;1690:89-95. [PMID: 29630859 DOI: 10.1016/j.brainres.2018.04.002] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 2.5] [Reference Citation Analysis]
37 Yaeger JD, Krupp KT, Jacobs BM, Onserio BO, Meyerink BL, Cain JT, Ronan PJ, Renner KJ, Dileone RJ, Summers CH. Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance from Pro- to Anti-stress Signaling and Behavior. Biological Psychiatry 2022. [DOI: 10.1016/j.biopsych.2021.12.019] [Reference Citation Analysis]
38 Moorman DE. The hypocretin/orexin system as a target for excessive motivation in alcohol use disorders. Psychopharmacology (Berl) 2018;235:1663-80. [PMID: 29508004 DOI: 10.1007/s00213-018-4871-2] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 3.0] [Reference Citation Analysis]
39 Flores Á, Valls-Comamala V, Costa G, Saravia R, Maldonado R, Berrendero F. The hypocretin/orexin system mediates the extinction of fear memories. Neuropsychopharmacology 2014;39:2732-41. [PMID: 24930888 DOI: 10.1038/npp.2014.146] [Cited by in Crossref: 77] [Cited by in F6Publishing: 69] [Article Influence: 9.6] [Reference Citation Analysis]
40 Penzo MA, Robert V, Tucciarone J, De Bundel D, Wang M, Van Aelst L, Darvas M, Parada LF, Palmiter RD, He M, Huang ZJ, Li B. The paraventricular thalamus controls a central amygdala fear circuit. Nature 2015;519:455-9. [PMID: 25600269 DOI: 10.1038/nature13978] [Cited by in Crossref: 245] [Cited by in F6Publishing: 228] [Article Influence: 35.0] [Reference Citation Analysis]
41 Hsu CW, Wang S. Changes in the Orexin System in Rats Exhibiting Learned Helplessness Behaviors. Brain Sci 2021;11:1634. [PMID: 34942932 DOI: 10.3390/brainsci11121634] [Reference Citation Analysis]
42 Arendt DH, Hassell J, Li H, Achua JK, Guarnieri DJ, Dileone RJ, Ronan PJ, Summers CH. Anxiolytic function of the orexin 2/hypocretin A receptor in the basolateral amygdala. Psychoneuroendocrinology 2014;40:17-26. [PMID: 24485472 DOI: 10.1016/j.psyneuen.2013.10.010] [Cited by in Crossref: 44] [Cited by in F6Publishing: 40] [Article Influence: 4.9] [Reference Citation Analysis]
43 Vargas I, Nguyen AM, Muench A, Bastien CH, Ellis JG, Perlis ML. Acute and Chronic Insomnia: What Has Time and/or Hyperarousal Got to Do with It? Brain Sci 2020;10:E71. [PMID: 32013124 DOI: 10.3390/brainsci10020071] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
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45 Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Motivational activation: a unifying hypothesis of orexin/hypocretin function. Nat Neurosci 2014;17:1298-303. [PMID: 25254979 DOI: 10.1038/nn.3810] [Cited by in Crossref: 223] [Cited by in F6Publishing: 207] [Article Influence: 27.9] [Reference Citation Analysis]
46 Blume SR, Nam H, Luz S, Bangasser DA, Bhatnagar S. Sex- and Age-dependent Effects of Orexin 1 Receptor Blockade on Open-Field Behavior and Neuronal Activity. Neuroscience 2018;381:11-21. [PMID: 29678754 DOI: 10.1016/j.neuroscience.2018.04.005] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 2.8] [Reference Citation Analysis]
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48 González JA, Jensen LT, Iordanidou P, Strom M, Fugger L, Burdakov D. Inhibitory Interplay between Orexin Neurons and Eating. Curr Biol 2016;26:2486-91. [PMID: 27546579 DOI: 10.1016/j.cub.2016.07.013] [Cited by in Crossref: 63] [Cited by in F6Publishing: 50] [Article Influence: 10.5] [Reference Citation Analysis]
49 Iio K, Saitoh T, Ohshita R, Hino T, Amezawa M, Takayama Y, Nagumo Y, Yamamoto N, Kutsumura N, Irukayama-tomobe Y, Ishikawa Y, Tanimura R, Yanagisawa M, Nagase H. Discovery of Orexin 2 Receptor Selective and Dual Orexin Receptor Agonists based on the Tetralin Structure: Switching of Receptor Selectivity by Chirality on the Tetralin Ring. Bioorganic & Medicinal Chemistry Letters 2022. [DOI: 10.1016/j.bmcl.2022.128555] [Reference Citation Analysis]
50 Gottschalk MG, Richter J, Ziegler C, Schiele MA, Mann J, Geiger MJ, Schartner C, Homola GA, Alpers GW, Büchel C, Fehm L, Fydrich T, Gerlach AL, Gloster AT, Helbig-Lang S, Kalisch R, Kircher T, Lang T, Lonsdorf TB, Pané-Farré CA, Ströhle A, Weber H, Zwanzger P, Arolt V, Romanos M, Wittchen HU, Hamm A, Pauli P, Reif A, Deckert J, Neufang S, Höfler M, Domschke K. Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes. Transl Psychiatry 2019;9:75. [PMID: 30718541 DOI: 10.1038/s41398-019-0415-8] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 4.0] [Reference Citation Analysis]
51 Stanojlovic M, Pallais JP, Kotz CM. Chemogenetic Modulation of Orexin Neurons Reverses Changes in Anxiety and Locomotor Activity in the A53T Mouse Model of Parkinson's Disease. Front Neurosci 2019;13:702. [PMID: 31417337 DOI: 10.3389/fnins.2019.00702] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
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53 Bonnavion P, Jackson AC, Carter ME, de Lecea L. Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses. Nat Commun 2015;6:6266. [PMID: 25695914 DOI: 10.1038/ncomms7266] [Cited by in Crossref: 91] [Cited by in F6Publishing: 86] [Article Influence: 13.0] [Reference Citation Analysis]
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55 Zhou W, Wang LQ, Shao YQ, Han X, Yu CX, Yuan F, Wang X, Weng SJ, Zhong YM, Yang XL. Orexin-A Intensifies Mouse Pupillary Light Response by Modulating Intrinsically Photosensitive Retinal Ganglion Cells. J Neurosci 2021;41:2566-80. [PMID: 33536197 DOI: 10.1523/JNEUROSCI.0217-20.2021] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
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57 Federici LM, Caliman IF, Molosh AI, Fitz SD, Truitt WA, Bonaventure P, Carpenter JS, Shekhar A, Johnson PL. Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model. Psychoneuroendocrinology 2016;65:127-37. [PMID: 26765933 DOI: 10.1016/j.psyneuen.2015.12.011] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.9] [Reference Citation Analysis]
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59 Cohen S, Ifergane G, Vainer E, Matar MA, Kaplan Z, Zohar J, Mathé AA, Cohen H. The wake-promoting drug modafinil stimulates specific hypothalamic circuits to promote adaptive stress responses in an animal model of PTSD. Transl Psychiatry 2016;6:e917. [PMID: 27727245 DOI: 10.1038/tp.2016.172] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 1.5] [Reference Citation Analysis]
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