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For: Tsuneki H, Murata S, Anzawa Y, Soeda Y, Tokai E, Wada T, Kimura I, Yanagisawa M, Sakurai T, Sasaoka T. Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice. Diabetologia 2008;51:657-67. [PMID: 18256806 DOI: 10.1007/s00125-008-0929-8] [Cited by in Crossref: 88] [Cited by in F6Publishing: 74] [Article Influence: 6.3] [Reference Citation Analysis]
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6 Tsuneki H, Wada T, Sasaoka T. Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders. Pharmacology & Therapeutics 2018;186:25-44. [DOI: 10.1016/j.pharmthera.2017.12.010] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 3.0] [Reference Citation Analysis]
7 Liu Y, Zhao Y, Guo L. Effects of orexin A on glucose metabolism in human hepatocellular carcinoma in vitro via PI3K/Akt/mTOR-dependent and -independent mechanism. Molecular and Cellular Endocrinology 2016;420:208-16. [DOI: 10.1016/j.mce.2015.11.002] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 2.5] [Reference Citation Analysis]
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12 Skrzypski M, Kaczmarek P, Le TT, Wojciechowicz T, Pruszyńska-Oszmalek E, Szczepankiewicz D, Sassek M, Arafat A, Wiedenmann B, Nowak KW, Strowski MZ. Effects of orexin A on proliferation, survival, apoptosis and differentiation of 3T3-L1 preadipocytes into mature adipocytes. FEBS Lett 2012;586:4157-64. [PMID: 23123090 DOI: 10.1016/j.febslet.2012.10.013] [Cited by in Crossref: 40] [Cited by in F6Publishing: 34] [Article Influence: 4.0] [Reference Citation Analysis]
13 Park J, Shim H, Na A, Bae J, Im S, Song D. Orexin A regulates plasma insulin and leptin levels in a time-dependent manner following a glucose load in mice. Diabetologia 2015;58:1542-50. [DOI: 10.1007/s00125-015-3573-0] [Cited by in Crossref: 25] [Cited by in F6Publishing: 22] [Article Influence: 3.6] [Reference Citation Analysis]
14 Xiang J, Zhang S, Xu R, Chu H, Biswas S, Yu S, Miao D, Li W, Li S, Brown AJ, Yang H, Xu Y, Li B, Liu H. Elevated HB-EGF expression in neural stem cells causes middle age obesity by suppressing Hypocretin/Orexin expression. FASEB J 2021;35:e21345. [PMID: 33715219 DOI: 10.1096/fj.202001945R] [Reference Citation Analysis]
15 Shen Y, Zhao Y, Zheng D, Chang X, Ju S, Guo L. Effects of orexin A on GLUT4 expression and lipid content via MAPK signaling in 3T3-L1 adipocytes. J Steroid Biochem Mol Biol 2013;138:376-83. [PMID: 23907013 DOI: 10.1016/j.jsbmb.2013.07.005] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 2.3] [Reference Citation Analysis]
16 Gupta A, Miegueu P, Lapointe M, Poirier P, Martin J, Bastien M, Tiwari S, Cianflone K. Acute post-bariatric surgery increase in orexin levels associates with preferential lipid profile improvement. PLoS One 2014;9:e84803. [PMID: 24400115 DOI: 10.1371/journal.pone.0084803] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 1.4] [Reference Citation Analysis]
17 Yu J, Song P, Perry R, Penfold C, Cooper AR. The Effectiveness of Green Tea or Green Tea Extract on Insulin Resistance and Glycemic Control in Type 2 Diabetes Mellitus: A Meta-Analysis. Diabetes Metab J 2017;41:251-62. [PMID: 28868822 DOI: 10.4093/dmj.2017.41.4.251] [Cited by in Crossref: 26] [Cited by in F6Publishing: 20] [Article Influence: 5.2] [Reference Citation Analysis]
18 Liu L, Wang Q, Liu A, Lan X, Huang Y, Zhao Z, Jie H, Chen J, Zhao Y. Physiological Implications of Orexins/Hypocretins on Energy Metabolism and Adipose Tissue Development. ACS Omega 2020;5:547-55. [PMID: 31956801 DOI: 10.1021/acsomega.9b03106] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 2.3] [Reference Citation Analysis]
19 Rani M, Kumar R, Krishan P. Role of orexins in the central and peripheral regulation of glucose homeostasis: Evidences & mechanisms. Neuropeptides 2018;68:1-6. [DOI: 10.1016/j.npep.2018.02.002] [Cited by in Crossref: 14] [Cited by in F6Publishing: 10] [Article Influence: 3.5] [Reference Citation Analysis]
20 Summers CH, Yaeger JDW, Staton CD, Arendt DH, Summers TR. Orexin/hypocretin receptor modulation of anxiolytic and antidepressive responses during social stress and decision-making: Potential for therapy. Brain Res 2020;1731:146085. [PMID: 30590027 DOI: 10.1016/j.brainres.2018.12.036] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 3.8] [Reference Citation Analysis]
21 Ramser A, Dridi S. Avian Orexin: Feed Intake Regulator or Something Else? Veterinary Sciences 2022;9:112. [DOI: 10.3390/vetsci9030112] [Reference Citation Analysis]
22 Yuan X, He F, Zheng F, Xu Y, Zou J. Interferon-gamma Facilitates Neurogenesis by Activating Wnt/β-catenin Cell Signaling Pathway via Promotion of STAT1 Regulation of the β-Catenin Promoter. Neuroscience 2020;448:219-33. [PMID: 32860934 DOI: 10.1016/j.neuroscience.2020.08.018] [Reference Citation Analysis]
23 Arafat AM, Kaczmarek P, Skrzypski M, Pruszyńska-Oszmałek E, Kołodziejski P, Adamidou A, Ruhla S, Szczepankiewicz D, Sassek M, Billert M, Wiedenmann B, Pfeiffer AF, Nowak KW, Strowski MZ. Glucagon regulates orexin A secretion in humans and rodents. Diabetologia 2014;57:2108-16. [PMID: 25063274 DOI: 10.1007/s00125-014-3335-4] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 1.4] [Reference Citation Analysis]
24 Santiago JCP, Otto M, Kern W, Baier PC, Hallschmid M. Relationship between cerebrospinal fluid concentrations of orexin A/hypocretin-1 and body composition in humans. Peptides 2018;102:26-30. [PMID: 29471000 DOI: 10.1016/j.peptides.2018.02.005] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
25 Chen Y, Feng R, Wang H, Wei R, Yang J, Wang L, Wang H, Zhang L, Hong TP, Wen J. High-fat diet induces early-onset diabetes in heterozygous Pax6 mutant mice. Diabetes Metab Res Rev 2014;30:467-75. [PMID: 24925705 DOI: 10.1002/dmrr.2572] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 0.9] [Reference Citation Analysis]
26 Wu S, Divall S, Wondisford F, Wolfe A. Reproductive tissues maintain insulin sensitivity in diet-induced obesity. Diabetes 2012;61:114-23. [PMID: 22076926 DOI: 10.2337/db11-0956] [Cited by in Crossref: 38] [Cited by in F6Publishing: 39] [Article Influence: 3.5] [Reference Citation Analysis]
27 Ickin Gulen M, Guven Bagla A, Yavuz O, Hismiogullari AA. Orexin and adiponectin in high fat diet–induced insulin resistance. Journal of Histotechnology 2019;42:3-12. [DOI: 10.1080/01478885.2018.1520952] [Reference Citation Analysis]
28 Azzam S, Schlatzer D, Nethery D, Saleh D, Li X, Akladious A, Chance MR, Strohl KP. Proteomic profiling of the hypothalamus in two mouse models of narcolepsy. Proteomics 2017;17. [PMID: 28544614 DOI: 10.1002/pmic.201600478] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.8] [Reference Citation Analysis]
29 Kodadek T, Cai D. Chemistry and biology of orexin signaling. Mol Biosyst 2010;6:1366-75. [PMID: 20532299 DOI: 10.1039/c003468a] [Cited by in Crossref: 31] [Cited by in F6Publishing: 29] [Article Influence: 2.6] [Reference Citation Analysis]
30 Donjacour CE, Aziz NA, Overeem S, Kalsbeek A, Pijl H, Lammers GJ. Glucose and fat metabolism in narcolepsy and the effect of sodium oxybate: a hyperinsulinemic-euglycemic clamp study. Sleep 2014;37:795-801. [PMID: 24899766 DOI: 10.5665/sleep.3592] [Cited by in Crossref: 24] [Cited by in F6Publishing: 21] [Article Influence: 3.0] [Reference Citation Analysis]
31 Kim SW, Cho KJ, Lee BI. Compensatory actions of orexinergic neurons in the lateral hypothalamus during metabolic or cortical challenges may enable the coupling of metabolic dysfunction and cortical dysfunction. Medical Hypotheses 2013;80:520-6. [DOI: 10.1016/j.mehy.2013.02.009] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
32 Razavinia F, Tehranian N, Sadatmahalleh SJ, Kazemnejad A, Khajetash S, Daryasari SRF, Pahlavan F, Jahanfar S. The influence of mode of delivery, anthropometric indices, and infant's sex on the maternal and cord blood orexin-A levels: A cohort study. J Obstet Gynaecol Res 2021;47:2363-70. [PMID: 33870593 DOI: 10.1111/jog.14758] [Reference Citation Analysis]
33 Fadel JR, Jolivalt CG, Reagan LP. Food for thought: the role of appetitive peptides in age-related cognitive decline. Ageing Res Rev 2013;12:764-76. [PMID: 23416469 DOI: 10.1016/j.arr.2013.01.009] [Cited by in Crossref: 45] [Cited by in F6Publishing: 44] [Article Influence: 5.0] [Reference Citation Analysis]
34 Sellayah D, Bharaj P, Sikder D. Orexin Is Required for Brown Adipose Tissue Development, Differentiation, and Function. Cell Metabolism 2011;14:478-90. [DOI: 10.1016/j.cmet.2011.08.010] [Cited by in Crossref: 174] [Cited by in F6Publishing: 158] [Article Influence: 15.8] [Reference Citation Analysis]
35 Tsuneki H, Kon K, Ito H, Yamazaki M, Takahara S, Toyooka N, Ishii Y, Sasahara M, Wada T, Yanagisawa M, Sakurai T, Sasaoka T. Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice. Endocrinology 2016;157:4146-57. [PMID: 27631554 DOI: 10.1210/en.2016-1404] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 2.3] [Reference Citation Analysis]
36 Jha PK, Foppen E, Kalsbeek A, Challet E. Sleep restriction acutely impairs glucose tolerance in rats. Physiol Rep 2016;4:e12839. [PMID: 27354542 DOI: 10.14814/phy2.12839] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 2.3] [Reference Citation Analysis]
37 Girault EM, Yi CX, Fliers E, Kalsbeek A. Orexins, feeding, and energy balance. Prog Brain Res 2012;198:47-64. [PMID: 22813969 DOI: 10.1016/B978-0-444-59489-1.00005-7] [Cited by in Crossref: 51] [Cited by in F6Publishing: 25] [Article Influence: 5.1] [Reference Citation Analysis]
38 Yilmaz E, Celik O, Celik N, Simsek Y, Celik E, Yildirim E. Serum orexin-A (OXA) level decreases in polycystic ovarian syndrome. Gynecological Endocrinology 2013;29:388-90. [DOI: 10.3109/09513590.2012.754874] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
39 Brownell SE, Conti B. Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice. Neurosci Lett 2010;472:29-32. [PMID: 20117171 DOI: 10.1016/j.neulet.2010.01.048] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
40 Mochizuki A, Nakayama K, Nakamura S, Dantsuji M, Kamijo R, Shioda S, Sakurai T, Ozeki M, Inoue T. Involvement of orexin in lipid accumulation in the liver. Journal of Oral Biosciences 2018;60:76-82. [DOI: 10.1016/j.job.2018.07.001] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
41 Erichsen JM, Calva CB, Reagan LP, Fadel JR. Intranasal insulin and orexins to treat age-related cognitive decline. Physiol Behav 2021;234:113370. [PMID: 33621561 DOI: 10.1016/j.physbeh.2021.113370] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
42 Mohammadi S, Moosaie F, Saghazadeh A, Mahmoudi M, Rezaei N. Metabolic profile in patients with narcolepsy: a systematic review and meta-analysis. Sleep Med 2021;81:268-84. [PMID: 33740593 DOI: 10.1016/j.sleep.2021.02.040] [Reference Citation Analysis]
43 Kalsbeek A, Yi CX, La Fleur SE, Fliers E. The hypothalamic clock and its control of glucose homeostasis. Trends Endocrinol Metab 2010;21:402-10. [PMID: 20303779 DOI: 10.1016/j.tem.2010.02.005] [Cited by in Crossref: 68] [Cited by in F6Publishing: 55] [Article Influence: 5.7] [Reference Citation Analysis]
44 Mohammadi S, Dolatshahi M, Zare-shahabadi A, Rahmani F. Untangling narcolepsy and diabetes: Pathomechanisms with eyes on therapeutic options. Brain Research 2019;1718:212-22. [DOI: 10.1016/j.brainres.2019.04.013] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
45 Milbank E, López M. Orexins/Hypocretins: Key Regulators of Energy Homeostasis. Front Endocrinol (Lausanne) 2019;10:830. [PMID: 31920958 DOI: 10.3389/fendo.2019.00830] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 4.7] [Reference Citation Analysis]
46 Adeghate E. Orexins: tissue localization, functions, and its relation to insulin secretion and diabetes mellitus. Vitam Horm. 2012;89:111-133. [PMID: 22640611 DOI: 10.1016/b978-0-12-394623-2.00007-x] [Cited by in Crossref: 12] [Cited by in F6Publishing: 4] [Article Influence: 1.2] [Reference Citation Analysis]
47 Skrzypski M, T. Le T, Kaczmarek P, Pruszynska-oszmalek E, Pietrzak P, Szczepankiewicz D, Kolodziejski PA, Sassek M, Arafat A, Wiedenmann B, Nowak KW, Strowski MZ. Orexin A stimulates glucose uptake, lipid accumulation and adiponectin secretion from 3T3-L1 adipocytes and isolated primary rat adipocytes. Diabetologia 2011;54:1841-52. [DOI: 10.1007/s00125-011-2152-2] [Cited by in Crossref: 61] [Cited by in F6Publishing: 53] [Article Influence: 5.5] [Reference Citation Analysis]
48 Deuschle M, Schilling C, Leweke FM, Enning F, Pollmächer T, Esselmann H, Wiltfang J, Frölich L, Heuser I. Hypocretin in cerebrospinal fluid is positively correlated with Tau and pTau. Neurosci Lett. 2014;561:41-45. [PMID: 24373987 DOI: 10.1016/j.neulet.2013.12.036] [Cited by in Crossref: 21] [Cited by in F6Publishing: 23] [Article Influence: 2.3] [Reference Citation Analysis]
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50 Brownell SE, Conti B. Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice. Neurosci Lett 2010;472:29-32. [PMID: 20117171 DOI: 10.1016/j.neulet.2010.01.048] [Cited by in Crossref: 41] [Cited by in F6Publishing: 37] [Article Influence: 3.4] [Reference Citation Analysis]
51 Yonezawa R, Wada T, Matsumoto N, Morita M, Sawakawa K, Ishii Y, Sasahara M, Tsuneki H, Saito S, Sasaoka T. Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet. American Journal of Physiology-Endocrinology and Metabolism 2012;303:E445-56. [DOI: 10.1152/ajpendo.00638.2011] [Cited by in Crossref: 65] [Cited by in F6Publishing: 62] [Article Influence: 6.5] [Reference Citation Analysis]
52 Zhang C, Sun C, Wang B, Yan P, Wu A, Yang G, Li W. Orexin-A stimulates the expression of GLUT4 in a glucose dependent manner in the liver of orange-spotted grouper (Epinephelus coioides). Comp Biochem Physiol A Mol Integr Physiol 2016;199:95-104. [PMID: 27264958 DOI: 10.1016/j.cbpa.2016.05.027] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
53 Cronin S, Lin A, Thompson K, Hoenerhoff M, Duncan RK. Hearing Loss and Otopathology Following Systemic and Intracerebroventricular Delivery of 2-Hydroxypropyl-Beta-Cyclodextrin. J Assoc Res Otolaryngol 2015;16:599-611. [PMID: 26055150 DOI: 10.1007/s10162-015-0528-6] [Cited by in Crossref: 23] [Cited by in F6Publishing: 17] [Article Influence: 3.3] [Reference Citation Analysis]
54 Sharma S, Kavuru M. Sleep and metabolism: an overview. Int J Endocrinol 2010;2010:270832. [PMID: 20811596 DOI: 10.1155/2010/270832] [Cited by in Crossref: 66] [Cited by in F6Publishing: 41] [Article Influence: 5.5] [Reference Citation Analysis]
55 Tsuneki H, Tokai E, Sugawara C, Wada T, Sakurai T, Sasaoka T. Hypothalamic orexin prevents hepatic insulin resistance induced by social defeat stress in mice. Neuropeptides 2013;47:213-9. [DOI: 10.1016/j.npep.2013.02.002] [Cited by in Crossref: 25] [Cited by in F6Publishing: 19] [Article Influence: 2.8] [Reference Citation Analysis]
56 Ichihara Y, Wada T, Soeda Y, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T. SH2-containing inositol 5'-phosphatase 2 selectively impairs hypothalamic insulin signalling and regulation of food intake in mice. J Neuroendocrinol 2013;25:372-82. [PMID: 23286299 DOI: 10.1111/jne.12014] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.6] [Reference Citation Analysis]
57 Zink AN, Perez-Leighton CE, Kotz CM. The orexin neuropeptide system: physical activity and hypothalamic function throughout the aging process. Front Syst Neurosci 2014;8:211. [PMID: 25408639 DOI: 10.3389/fnsys.2014.00211] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 2.3] [Reference Citation Analysis]
58 Nixon JP, Mavanji V, Butterick TA, Billington CJ, Kotz CM, Teske JA. Sleep disorders, obesity, and aging: the role of orexin. Ageing Res Rev 2015;20:63-73. [PMID: 25462194 DOI: 10.1016/j.arr.2014.11.001] [Cited by in Crossref: 61] [Cited by in F6Publishing: 51] [Article Influence: 7.6] [Reference Citation Analysis]
59 Moslehi E, Minasian V, Sadeghi H. Subcutaneous Adipose Tissue Browning, Serum Orexin-A, and Insulin Resistance Following Aerobic Exercise in High-Fat Diet Obesity Male Wistar Rats. Int J Prev Med 2021;12:132. [PMID: 34912508 DOI: 10.4103/ijpvm.IJPVM_110_19] [Reference Citation Analysis]
60 Beitinger PA, Fulda S, Dalal MA, Wehrle R, Keckeis M, Wetter TC, Han F, Pollmächer T, Schuld A. Glucose tolerance in patients with narcolepsy. Sleep 2012;35:231-6. [PMID: 22294813 DOI: 10.5665/sleep.1628] [Cited by in Crossref: 27] [Cited by in F6Publishing: 20] [Article Influence: 2.7] [Reference Citation Analysis]
61 Wan X, Liu Y, Zhao Y, Sun X, Fan D, Guo L. Orexin A affects HepG2 human hepatocellular carcinoma cells glucose metabolism via HIF-1α-dependent and -independent mechanism. PLoS One 2017;12:e0184213. [PMID: 28886081 DOI: 10.1371/journal.pone.0184213] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 1.8] [Reference Citation Analysis]
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63 Xu T, Yang Y, Ward R, Gao L, Liu Y. Orexin receptors: Multi-functional therapeutic targets for sleeping disorders, eating disorders, drug addiction, cancers and other physiological disorders. Cellular Signalling 2013;25:2413-23. [DOI: 10.1016/j.cellsig.2013.07.025] [Cited by in Crossref: 68] [Cited by in F6Publishing: 65] [Article Influence: 7.6] [Reference Citation Analysis]
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