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For: Matsuki T, Sakurai T. Orexins and Orexin Receptors: From Molecules to Integrative Physiology. In: Civelli O, Zhou Q, editors. Orphan G Protein-Coupled Receptors and Novel Neuropeptides. Berlin: Springer Berlin Heidelberg; 2008. pp. 27-55. [DOI: 10.1007/400_2007_047] [Cited by in Crossref: 51] [Cited by in F6Publishing: 45] [Reference Citation Analysis]
Number Citing Articles
1 Domínguez L, Morona R, Joven A, González A, López JM. Immunohistochemical localization of orexins (hypocretins) in the brain of reptiles and its relation to monoaminergic systems. Journal of Chemical Neuroanatomy 2010;39:20-34. [DOI: 10.1016/j.jchemneu.2009.07.007] [Cited by in Crossref: 27] [Cited by in F6Publishing: 24] [Article Influence: 2.3] [Reference Citation Analysis]
2 Boss C, Roch-brisbare C, Steiner MA, Treiber A, Dietrich H, Jenck F, von Raumer M, Sifferlen T, Brotschi C, Heidmann B, Williams JT, Aissaoui H, Siegrist R, Gatfield J. Structure-Activity Relationship, Biological, and Pharmacological Characterization of the Proline Sulfonamide ACT-462206: a Potent, Brain-Penetrant Dual Orexin 1/Orexin 2 Receptor Antagonist. ChemMedChem 2014;9:2486-96. [DOI: 10.1002/cmdc.201402258] [Cited by in Crossref: 24] [Cited by in F6Publishing: 17] [Article Influence: 3.0] [Reference Citation Analysis]
3 Boss C. Orexin receptor antagonists--a patent review (2010 to August 2014). Expert Opin Ther Pat 2014;24:1367-81. [PMID: 25407283 DOI: 10.1517/13543776.2014.978859] [Cited by in Crossref: 13] [Cited by in F6Publishing: 14] [Article Influence: 1.9] [Reference Citation Analysis]
4 Liguori G, Pavone LM, Assisi L, Langella E, Tafuri S, Mirabella N, Costagliola A, Vittoria A. Expression of orexin B and its receptor 2 in rat testis. General and Comparative Endocrinology 2017;242:66-73. [DOI: 10.1016/j.ygcen.2015.11.015] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 2.8] [Reference Citation Analysis]
5 Li B, Chang L, Peng X. Orexin 2 receptor in the nucleus accumbens is critical for the modulation of acute stress-induced anxiety. Psychoneuroendocrinology 2021;131:105317. [PMID: 34111776 DOI: 10.1016/j.psyneuen.2021.105317] [Reference Citation Analysis]
6 Li GY, Zhuang QX, Zhang XY, Wang JJ, Zhu JN. Ionic Mechanisms Underlying the Excitatory Effect of Orexin on Rat Subthalamic Nucleus Neurons. Front Cell Neurosci 2019;13:153. [PMID: 31105528 DOI: 10.3389/fncel.2019.00153] [Reference Citation Analysis]
7 Kojima K, Kamijo M, Kageyama H, Uchiyama M, Shioda S, Matsuda K. Neuronal relationship between orexin-A- and neuropeptide Y-induced orexigenic actions in goldfish. Neuropeptides 2009;43:63-71. [PMID: 19261328 DOI: 10.1016/j.npep.2009.01.004] [Cited by in Crossref: 42] [Cited by in F6Publishing: 38] [Article Influence: 3.2] [Reference Citation Analysis]
8 Ramser A, Dridi S. Avian Orexin: Feed Intake Regulator or Something Else? Veterinary Sciences 2022;9:112. [DOI: 10.3390/vetsci9030112] [Reference Citation Analysis]
9 Urbańska A, Sokołowska P, Woldan-Tambor A, Biegańska K, Brix B, Jöhren O, Namiecińska M, Zawilska JB. Orexins/hypocretins acting at Gi protein-coupled OX 2 receptors inhibit cyclic AMP synthesis in the primary neuronal cultures. J Mol Neurosci 2012;46:10-7. [PMID: 21547533 DOI: 10.1007/s12031-011-9526-2] [Cited by in Crossref: 21] [Cited by in F6Publishing: 23] [Article Influence: 1.9] [Reference Citation Analysis]
10 Han Y, Yuan K, Zheng Y, Lu L. Orexin Receptor Antagonists as Emerging Treatments for Psychiatric Disorders. Neurosci Bull 2020;36:432-48. [PMID: 31782044 DOI: 10.1007/s12264-019-00447-9] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 4.7] [Reference Citation Analysis]
11 Karasawa H, Yakabi S, Wang L, Taché Y. Orexin-1 receptor mediates the increased food and water intake induced by intracerebroventricular injection of the stable somatostatin pan-agonist, ODT8-SST in rats. Neurosci Lett 2014;576:88-92. [PMID: 24915296 DOI: 10.1016/j.neulet.2014.05.063] [Cited by in Crossref: 13] [Cited by in F6Publishing: 9] [Article Influence: 1.6] [Reference Citation Analysis]
12 Adeghate E, Fernandez-Cabezudo M, Hameed R, El-Hasasna H, El Wasila M, Abbas T, Al-Ramadi B. Orexin-1 receptor co-localizes with pancreatic hormones in islet cells and modulates the outcome of streptozotocin-induced diabetes mellitus. PLoS One 2010;5:e8587. [PMID: 20062799 DOI: 10.1371/journal.pone.0008587] [Cited by in Crossref: 16] [Cited by in F6Publishing: 13] [Article Influence: 1.3] [Reference Citation Analysis]
13 Guo F, Gao S, Xu L, Sun X, Zhang N, Gong Y, Luan X. Arcuate Nucleus Orexin-A Signaling Alleviates Cisplatin-Induced Nausea and Vomiting Through the Paraventricular Nucleus of the Hypothalamus in Rats. Front Physiol 2018;9:1811. [PMID: 30618823 DOI: 10.3389/fphys.2018.01811] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
14 Zhang J, Li B, Yu L, He YC, Li HZ, Zhu JN, Wang JJ. A role for orexin in central vestibular motor control. Neuron 2011;69:793-804. [PMID: 21338887 DOI: 10.1016/j.neuron.2011.01.026] [Cited by in Crossref: 69] [Cited by in F6Publishing: 71] [Article Influence: 6.3] [Reference Citation Analysis]
15 Chang X, Suo L, Xu N, Zhao Y. Orexin-A Stimulates Insulin Secretion Through the Activation of the OX1 Receptor and Mammalian Target of Rapamycin in Rat Insulinoma Cells. Pancreas 2019;48:568-73. [PMID: 30946236 DOI: 10.1097/MPA.0000000000001280] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.7] [Reference Citation Analysis]
16 Yu L, Zhang XY, Chen ZP, Zhuang QX, Zhu JN, Wang JJ. Orexin excites rat inferior vestibular nuclear neurons via co-activation of OX1 and OX 2 receptors. J Neural Transm (Vienna) 2015;122:747-55. [PMID: 25371350 DOI: 10.1007/s00702-014-1330-z] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
17 Xiao X, Yeghiazaryan G, Hess S, Klemm P, Sieben A, Kleinridders A, Morgan DA, Wunderlich FT, Rahmouni K, Kong D, Scammell TE, Lowell BB, Kloppenburg P, Brüning JC, Hausen AC. Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nat Commun 2021;12:5249. [PMID: 34475397 DOI: 10.1038/s41467-021-25380-2] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
18 Boss C, Roch C. Recent trends in orexin research—2010 to 2015. Bioorganic & Medicinal Chemistry Letters 2015;25:2875-87. [DOI: 10.1016/j.bmcl.2015.05.012] [Cited by in Crossref: 47] [Cited by in F6Publishing: 39] [Article Influence: 6.7] [Reference Citation Analysis]
19 Heese K. G proteins, p60TRP, and neurodegenerative diseases. Mol Neurobiol 2013;47:1103-11. [PMID: 23345134 DOI: 10.1007/s12035-013-8410-1] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.0] [Reference Citation Analysis]
20 Matsuda K, Matsumura K, Shimizu SS, Nakamachi T, Konno N. Neuropeptide Y-Induced Orexigenic Action Is Attenuated by the Orexin Receptor Antagonist in Bullfrog Larvae. Front Neurosci 2017;11:176. [PMID: 28420957 DOI: 10.3389/fnins.2017.00176] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
21 Zhang G, Wu XH, Xu GZ, Weng SJ, Yang XL, Zhong YM. Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina. Neuropharmacology 2018;133:38-50. [PMID: 29325900 DOI: 10.1016/j.neuropharm.2018.01.007] [Cited by in Crossref: 6] [Cited by in F6Publishing: 8] [Article Influence: 1.5] [Reference Citation Analysis]
22 Bond DS, Roth J, Nash JM, Wing RR. Migraine and obesity: epidemiology, possible mechanisms and the potential role of weight loss treatment. Obes Rev 2011;12:e362-71. [PMID: 20673279 DOI: 10.1111/j.1467-789X.2010.00791.x] [Cited by in Crossref: 71] [Cited by in F6Publishing: 37] [Article Influence: 6.5] [Reference Citation Analysis]
23 Wang C, Han X, Sun X, Guo F, Luan X, Xu L. Orexin-A signaling in the paraventricular nucleus promote gastric acid secretion and gastric motility through the activation neuropeptide Y Y1 receptors and modulated by the hypothalamic lateral area. Neuropeptides 2019;74:24-33. [PMID: 30700376 DOI: 10.1016/j.npep.2019.01.005] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.7] [Reference Citation Analysis]
24 Zhou W, Wang LQ, Shao YQ, Han X, Yu CX, Yuan F, Wang X, Weng SJ, Zhong YM, Yang XL. Orexin-A Intensifies Mouse Pupillary Light Response by Modulating Intrinsically Photosensitive Retinal Ganglion Cells. J Neurosci 2021;41:2566-80. [PMID: 33536197 DOI: 10.1523/JNEUROSCI.0217-20.2021] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
25 Yuan W, Wang H, Gong Y. Prevention of cisplatin-induced nausea and vomiting by seabuckthorn (Hippophae rhamnoides L.) seed oil: Insights at the level of orexin-A in rats. Iran J Basic Med Sci 2021;24:248-55. [PMID: 33953865 DOI: 10.22038/ijbms.2020.47599.10973] [Reference Citation Analysis]
26 Vaughn LK, Denning G, Stuhr KL, de Wit H, Hill MN, Hillard CJ. Endocannabinoid signalling: has it got rhythm? Br J Pharmacol 2010;160:530-43. [PMID: 20590563 DOI: 10.1111/j.1476-5381.2010.00790.x] [Cited by in Crossref: 88] [Cited by in F6Publishing: 82] [Article Influence: 7.3] [Reference Citation Analysis]
27 Ruan HZ, Wang LQ, Yuan F, Weng SJ, Zhong YM. Orexin-A differentially modulates inhibitory and excitatory synaptic transmission in rat inner retina. Neuropharmacology 2021;187:108492. [PMID: 33582153 DOI: 10.1016/j.neuropharm.2021.108492] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
28 Boss C, Gatfield J, Brotschi C, Heidmann B, Sifferlen T, von Raumer M, Schmidt G, Williams JT, Treiber A, Roch C. The Quest for the Best Dual Orexin Receptor Antagonist (Daridorexant) for the Treatment of Insomnia Disorders. ChemMedChem 2020;15:2286-305. [PMID: 32937014 DOI: 10.1002/cmdc.202000453] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
29 Koval’zon VM. Central mechanisms of the sleep-wakefulness cycle control. Hum Physiol 2011;37:500-8. [DOI: 10.1134/s0362119711040116] [Cited by in Crossref: 10] [Article Influence: 0.9] [Reference Citation Analysis]
30 Guillaumin MCC, Burdakov D. Neuropeptides as Primary Mediators of Brain Circuit Connectivity. Front Neurosci 2021;15:644313. [PMID: 33776641 DOI: 10.3389/fnins.2021.644313] [Reference Citation Analysis]
31 Civelli O, Reinscheid RK, Zhang Y, Wang Z, Fredriksson R, Schiöth HB. G protein-coupled receptor deorphanizations. Annu Rev Pharmacol Toxicol 2013;53:127-46. [PMID: 23020293 DOI: 10.1146/annurev-pharmtox-010611-134548] [Cited by in Crossref: 111] [Cited by in F6Publishing: 113] [Article Influence: 11.1] [Reference Citation Analysis]
32 Walker LC, Ch’ng SS, Lawrence AJ. Role of Lateral Hypothalamic Orexin (Hypocretin) Neurons in Alcohol Use and Abuse: Recent Advances. Curr Pharmacol Rep 2016;2:241-52. [DOI: 10.1007/s40495-016-0069-7] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
33 Uslaner JM, Herring WJ, Coleman PJ. The Discovery of Suvorexant: Lessons Learned That Can Be Applied to Other CNS Drug Development Efforts. ACS Pharmacol Transl Sci 2020;3:161-8. [PMID: 32259095 DOI: 10.1021/acsptsci.9b00110] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
34 Sánchez-García A, Cabral-Pacheco GA, Zomosa-Signoret VC, Ortiz-López R, Camacho A, Tabera-Tarello PM, Garnica-López JA, Vidaltamayo R. Modular organization of a hypocretin gene minimal promoter. Mol Med Rep 2018;17:2263-70. [PMID: 29207107 DOI: 10.3892/mmr.2017.8142] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
35 Zheng C, Deng QQ, Liu LL, Wang MY, Zhang G, Sheng WL, Weng SJ, Yang XL, Zhong YM. Orexin-A differentially modulates AMPA-preferring responses of ganglion cells and amacrine cells in rat retina. Neuropharmacology 2015;93:80-93. [PMID: 25656479 DOI: 10.1016/j.neuropharm.2015.01.016] [Cited by in Crossref: 10] [Cited by in F6Publishing: 13] [Article Influence: 1.4] [Reference Citation Analysis]
36 Biegańska K, Sokołowska P, Jöhren O, Zawilska JB. Orexin A suppresses the growth of rat C6 glioma cells via a caspase-dependent mechanism. J Mol Neurosci 2012;48:706-12. [PMID: 22588980 DOI: 10.1007/s12031-012-9799-0] [Cited by in Crossref: 21] [Cited by in F6Publishing: 18] [Article Influence: 2.1] [Reference Citation Analysis]
37 Zarrabian S, Riahi E, Karimi S, Razavi Y, Haghparast A. The potential role of the orexin reward system in future treatments for opioid drug abuse. Brain Research 2020;1731:146028. [DOI: 10.1016/j.brainres.2018.11.023] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 5.5] [Reference Citation Analysis]
38 Viskaitis P, Arnold M, Garau C, Jensen LT, Fugger L, Peleg-Raibstein D, Burdakov D. Ingested non-essential amino acids recruit brain orexin cells to suppress eating in mice. Curr Biol 2022:S0960-9822(22)00337-2. [PMID: 35316652 DOI: 10.1016/j.cub.2022.02.067] [Cited by in Crossref: 2] [Article Influence: 2.0] [Reference Citation Analysis]
39 Williams JT, Gatfield J, Roch C, Treiber A, Jenck F, Bolli MH, Brotschi C, Sifferlen T, Heidmann B, Boss C. Discovery and optimisation of 1-acyl-2-benzylpyrrolidines as potent dual orexin receptor antagonists. Med Chem Commun 2015;6:1054-64. [DOI: 10.1039/c5md00074b] [Cited by in Crossref: 5] [Article Influence: 0.7] [Reference Citation Analysis]
40 Kagerer SM, Eichholz C, Jöhren O. Orexins/hypocretins increase the promoter activity of selective steroidogenic enzymes. Peptides 2011;32:839-43. [PMID: 21256172 DOI: 10.1016/j.peptides.2011.01.004] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 0.6] [Reference Citation Analysis]
41 Liu C, Xue Y, Liu M, Wang Y, Liu Z, Diao H, Chen L. Orexins increase the firing activity of nigral dopaminergic neurons and participate in motor control in rats. J Neurochem 2018;147:380-94. [DOI: 10.1111/jnc.14568] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 2.3] [Reference Citation Analysis]
42 Nguyen PH, Greene E, Kong BW, Bottje W, Anthony N, Dridi S. Acute Heat Stress Alters the Expression of Orexin System in Quail Muscle. Front Physiol 2017;8:1079. [PMID: 29311994 DOI: 10.3389/fphys.2017.01079] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 2.0] [Reference Citation Analysis]
43 Hu B, Yang N, Qiao QC, Hu ZA, Zhang J. Roles of the orexin system in central motor control. Neurosci Biobehav Rev 2015;49:43-54. [PMID: 25511388 DOI: 10.1016/j.neubiorev.2014.12.005] [Cited by in Crossref: 38] [Cited by in F6Publishing: 30] [Article Influence: 4.8] [Reference Citation Analysis]
44 Guo F, Xu L, Gao S, Sun X, Zhang N, Gong Y. Effect of orexin-A in the arcuate nucleus on cisplatin-induced gastric side effects in rats. Neuroscience Research 2019;143:53-60. [DOI: 10.1016/j.neures.2018.06.001] [Cited by in Crossref: 5] [Cited by in F6Publishing: 7] [Article Influence: 1.7] [Reference Citation Analysis]
45 Gatfield J, Brisbare-Roch C, Jenck F, Boss C. Orexin receptor antagonists: a new concept in CNS disorders? ChemMedChem 2010;5:1197-214. [PMID: 20544785 DOI: 10.1002/cmdc.201000132] [Cited by in Crossref: 60] [Cited by in F6Publishing: 56] [Article Influence: 5.0] [Reference Citation Analysis]
46 Kagerer SM, Jöhren O. Interactions of orexins/hypocretins with adrenocortical functions. Acta Physiol (Oxf) 2010;198:361-71. [PMID: 19719797 DOI: 10.1111/j.1748-1716.2009.02034.x] [Cited by in Crossref: 26] [Cited by in F6Publishing: 22] [Article Influence: 2.0] [Reference Citation Analysis]
47 Woldan-Tambor A, Biegańska K, Wiktorowska-Owczarek A, Zawilska JB. Activation of orexin/hypocretin type 1 receptors stimulates cAMP synthesis in primary cultures of rat astrocytes. Pharmacol Rep 2011;63:717-23. [PMID: 21857082 DOI: 10.1016/s1734-1140(11)70583-7] [Cited by in Crossref: 18] [Cited by in F6Publishing: 10] [Article Influence: 1.6] [Reference Citation Analysis]
48 Adeghate E, Lotfy M, D'Souza C, Alseiari SM, Alsaadi AA, Qahtan SA. Hypocretin/orexin modulates body weight and the metabolism of glucose and insulin. Diabetes Metab Res Rev 2020;36:e3229. [PMID: 31655012 DOI: 10.1002/dmrr.3229] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
49 Liu F, Weng SJ, Yang XL, Zhong YM. Orexin-A potentiates L-type calcium/barium currents in rat retinal ganglion cells. Neuroscience 2015;305:225-37. [PMID: 26259903 DOI: 10.1016/j.neuroscience.2015.08.008] [Cited by in Crossref: 11] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
50 Torterolo P, Ramos OV, Sampogna S, Chase MH. Hypocretinergic neurons are activated in conjunction with goal-oriented survival-related motor behaviors. Physiol Behav 2011;104:823-30. [PMID: 21839102 DOI: 10.1016/j.physbeh.2011.07.032] [Cited by in Crossref: 18] [Cited by in F6Publishing: 16] [Article Influence: 1.6] [Reference Citation Analysis]