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For: Van Lam van T, Ivanova T, Hardes K, Heindl MR, Morty RE, Böttcher-Friebertshäuser E, Lindberg I, Than ME, Dahms SO, Steinmetzer T. Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin. ChemMedChem 2019;14:673-85. [PMID: 30680958 DOI: 10.1002/cmdc.201800807] [Cited by in Crossref: 16] [Cited by in F6Publishing: 17] [Article Influence: 5.3] [Reference Citation Analysis]
Number Citing Articles
1 [DOI: 10.1101/2020.04.15.042085] [Cited by in Crossref: 39] [Cited by in F6Publishing: 9] [Reference Citation Analysis]
2 Zhang Y, Tang LV. Overview of Targets and Potential Drugs of SARS-CoV-2 According to the Viral Replication. J Proteome Res 2021;20:49-59. [PMID: 33347311 DOI: 10.1021/acs.jproteome.0c00526] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
3 Izaguirre G. The Proteolytic Regulation of Virus Cell Entry by Furin and Other Proprotein Convertases. Viruses 2019;11:E837. [PMID: 31505793 DOI: 10.3390/v11090837] [Cited by in Crossref: 68] [Cited by in F6Publishing: 64] [Article Influence: 22.7] [Reference Citation Analysis]
4 Abassi ZA, Skorecki K, Heyman SN, Kinaneh S, Armaly Z. Covid-19 infection and mortality: a physiologist's perspective enlightening clinical features and plausible interventional strategies. Am J Physiol Lung Cell Mol Physiol 2020;318:L1020-2. [PMID: 32207983 DOI: 10.1152/ajplung.00097.2020] [Cited by in Crossref: 35] [Cited by in F6Publishing: 37] [Article Influence: 17.5] [Reference Citation Analysis]
5 Das BS, Das NC, Swain SS, Mukherjee S, Bhattacharya D. Andrographolide induces anti-SARS-CoV-2 response through host-directed mechanism: an in silico study. Future Virology. [DOI: 10.2217/fvl-2021-0171] [Reference Citation Analysis]
6 Devi KP, Pourkarim MR, Thijssen M, Sureda A, Khayatkashani M, Cismaru CA, Neagoe IB, Habtemariam S, Razmjouei S, Khayat Kashani HR. A perspective on the applications of furin inhibitors for the treatment of SARS-CoV-2. Pharmacol Rep 2022. [PMID: 35031970 DOI: 10.1007/s43440-021-00344-x] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
7 Osman EEA, Rehemtulla A, Neamati N. Why All the Fury over Furin? J Med Chem 2021. [PMID: 34340303 DOI: 10.1021/acs.jmedchem.1c00518] [Reference Citation Analysis]
8 Löw K, Hardes K, Fedeli C, Seidah NG, Constam DB, Pasquato A, Steinmetzer T, Roulin A, Kunz S. A novel cell-based sensor detecting the activity of individual basic proprotein convertases. FEBS J 2019;286:4597-620. [PMID: 31276291 DOI: 10.1111/febs.14979] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.7] [Reference Citation Analysis]
9 Bestle D, Heindl MR, Limburg H, Van Lam van T, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk HD, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E. TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells. Life Sci Alliance 2020;3:e202000786. [PMID: 32703818 DOI: 10.26508/lsa.202000786] [Cited by in Crossref: 185] [Cited by in F6Publishing: 199] [Article Influence: 92.5] [Reference Citation Analysis]
10 Kocyigit A, Sogut O, Durmus E, Kanimdan E, Guler EM, Kaplan O, Yenigun VB, Eren C, Ozman Z, Yasar O. Circulating furin, IL-6, and presepsin levels and disease severity in SARS-CoV-2-infected patients. Sci Prog 2021;104:368504211026119. [PMID: 34187224 DOI: 10.1177/00368504211026119] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
11 Barile E, Baggio C, Gambini L, Shiryaev SA, Strongin AY, Pellecchia M. Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming. Molecules 2020;25:E2424. [PMID: 32455942 DOI: 10.3390/molecules25102424] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 6.0] [Reference Citation Analysis]
12 Lam van TV, Heindl MR, Schlutt C, Böttcher-Friebertshäuser E, Bartenschlager R, Klebe G, Brandstetter H, Dahms SO, Steinmetzer T. The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin. ACS Med Chem Lett 2021;12:426-32. [PMID: 33732412 DOI: 10.1021/acsmedchemlett.0c00651] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 5.0] [Reference Citation Analysis]
13 Vianello A, Del Turco S, Babboni S, Silvestrini B, Ragusa R, Caselli C, Melani L, Fanucci L, Basta G. The Fight against COVID-19 on the Multi-Protease Front and Surroundings: Could an Early Therapeutic Approach with Repositioning Drugs Prevent the Disease Severity? Biomedicines 2021;9:710. [PMID: 34201505 DOI: 10.3390/biomedicines9070710] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
14 Nejat R, Sadr AS. Are losartan and imatinib effective against SARS-CoV2 pathogenesis? A pathophysiologic-based in silico study. In Silico Pharmacol 2021;9:1. [PMID: 33294307 DOI: 10.1007/s40203-020-00058-7] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 3.5] [Reference Citation Analysis]
15 Gioia M, Ciaccio C, Calligari P, De Simone G, Sbardella D, Tundo G, Fasciglione GF, Di Masi A, Di Pierro D, Bocedi A, Ascenzi P, Coletta M. Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches. Biochem Pharmacol 2020;182:114225. [PMID: 32956643 DOI: 10.1016/j.bcp.2020.114225] [Cited by in Crossref: 26] [Cited by in F6Publishing: 25] [Article Influence: 13.0] [Reference Citation Analysis]
16 Khattab ESAEH, Ragab A, Abol-Ftouh MA, Elhenawy AA. Therapeutic strategies for Covid-19 based on molecular docking and dynamic studies to the ACE-2 receptors, Furin, and viral spike proteins. J Biomol Struct Dyn 2021;:1-19. [PMID: 34647855 DOI: 10.1080/07391102.2021.1989036] [Reference Citation Analysis]
17 Vankadari N. Structure of Furin Protease Binding to SARS-CoV-2 Spike Glycoprotein and Implications for Potential Targets and Virulence. J Phys Chem Lett 2020;11:6655-63. [PMID: 32787225 DOI: 10.1021/acs.jpclett.0c01698] [Cited by in Crossref: 19] [Cited by in F6Publishing: 15] [Article Influence: 9.5] [Reference Citation Analysis]
18 Lewandowska-Goch MA, Kwiatkowska A, Łepek T, Ly K, Navals P, Gagnon H, Dory YL, Prahl A, Day R. Design and Structure-Activity Relationship of a Potent Furin Inhibitor Derived from Influenza Hemagglutinin. ACS Med Chem Lett 2021;12:365-72. [PMID: 33738063 DOI: 10.1021/acsmedchemlett.0c00386] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 4.0] [Reference Citation Analysis]
19 Omotuyi IO, Nash O, Ajiboye BO, Olumekun VO, Oyinloye BE, Osuntokun OT, Olonisakin A, Ajayi AO, Olusanya O, Akomolafe FS, Adelakun N. Aframomum melegueta secondary metabolites exhibit polypharmacology against SARS-CoV-2 drug targets: in vitro validation of furin inhibition. Phytother Res 2021;35:908-19. [PMID: 32964551 DOI: 10.1002/ptr.6843] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
20 Naveca FG, Nascimento V, Souza V, Corado AL, Nascimento F, Silva G, Mejía MC, Brandão MJ, Costa Á, Duarte D, Pessoa K, Jesus M, Gonçalves L, Fernandes C, Mattos T, Abdalla L, Santos JH, Martins A, Chui FM, Val FF, de Melo GC, Xavier MS, Sampaio VS, Mourão MP, Lacerda MV, Batista ÉLR, Magalhães ALÁ, Dábilla N, Pereira LCG, Vinhal F, Miyajima F, Dias FBS, Dos Santos ER, Coêlho D, Ferraz M, Lins R, Wallau GL, Delatorre E, Gräf T, Siqueira MM, Resende PC, Bello G; Fiocruz COVID-19 Genomic Surveillance Network. Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil. Microbiol Spectr 2022;10:e0236621. [PMID: 35196783 DOI: 10.1128/spectrum.02366-21] [Cited by in Crossref: 5] [Cited by in F6Publishing: 2] [Article Influence: 5.0] [Reference Citation Analysis]