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Jun 15, 2003 (publication date) through Nov 27, 2024
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World Journal of Gastroenterology
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1007-9327
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Yue CM, Deng DJ, Bi MX, Guo LP, Lu SH. Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma. World J Gastroenterol 2003; 9(6): 1174-1178 [PMID: 12800218 DOI: 10.3748/wjg.v9.i6.1174] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v9/i6/1174.htm |
| Number | Citing Articles |
| 1 |
Ashkaun Shaterian, Steven Kao, Lin Chen, Luisa A. DiPietro, Raul Coimbra, Brian P. Eliceiri, Andrew Baird. The candidate tumor suppressor gene Ecrg4 as a wound terminating factor in cutaneous injury. Archives of Dermatological Research 2013; 305(2): 141 doi: 10.1007/s00403-012-1276-7
|
| 2 |
Zhenyu Ye, Yecheng Li, Jiaming Xie, Zhenyu Feng, Xiaodong Yang, Yong Wu, Yuwei Pu, Jiawei Gao, Xiangrong Xu, Zhaobi Zhu, Wei Li, Wei Chen, Chungen Xing. Integrated bioinformatics identifies the dysregulation induced by aberrant gene methylation in colorectal carcinoma. Genes & Diseases 2021; 8(4): 521 doi: 10.1016/j.gendis.2020.04.008
|
| 3 |
Wei Li, Xinrui Liu, Bo Zhang, Dongxue Qi, Lihong Zhang, Yuhong Jin, Hongfa Yang. Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion. Journal of Experimental & Clinical Cancer Research 2010; 29(1) doi: 10.1186/1756-9966-29-89
|
| 4 |
Gao-Yan Tang, Guo-Jun Tang, Lu Yin, Chen Chao, Ren Zhou, Guo-Ping Ren, Jia-Yu Chen, Wei Zhang. ECRG4 acts as a tumor suppressor gene frequently hypermethylated in human breast cancer. Bioscience Reports 2019; 39(5) doi: 10.1042/BSR20190087
|
| 5 |
Daniela Cabuzu, Suresh K. Ramakrishnan, Matthias B. Moor, Dusan Harmacek, Muriel Auberson, Fanny Durussel, Olivier Bonny, Franziska Theilig. Loss of Ecrg4 improves calcium oxalate nephropathy. PLOS ONE 2022; 17(10): e0275972 doi: 10.1371/journal.pone.0275972
|
| 6 |
Tetsuo Moriguchi, Shun Kaneumi, Shuji Takeda, Kei Enomoto, Shyam Kumar Mishra, Tetsuro Miki, Uichi Koshimizu, Hidemitsu Kitamura, Toru Kondo. Ecrg4 contributes to the anti-glioma immunosurveillance through type-I interferon signaling. OncoImmunology 2016; 5(12): e1242547 doi: 10.1080/2162402X.2016.1242547
|
| 7 |
Farhad Kosari, Alexander S. Parker, Dagmar Marie Kube, Christine M. Lohse, Bradley C. Leibovich, Michael L. Blute, John C. Cheville, George Vasmatzis. Clear Cell Renal Cell Carcinoma: Gene Expression Analyses Identify a Potential Signature for Tumor Aggressiveness. Clinical Cancer Research 2005; 11(14): 5128 doi: 10.1158/1078-0432.CCR-05-0073
|
| 8 |
Huang Xiao-Ping, Rong Tie-Hua, Lin Peng, Wu Qiu-Liang, Yao Guang-Yu, Hou Jing-Hui, Su Xiao-Dong, Li Xiao-Dong, Li Bao-Jiang, Zhang Peng-Yuan, Long Kai, Huang Zhi-Fan. Cyclin D1 overexpression in esophageal cancer from southern China and its clinical significance. Cancer Letters 2006; 231(1): 94 doi: 10.1016/j.canlet.2005.01.040
|
| 9 |
XUE-LEI WANG, YUE LI, XIAO-YAN CHENG, QING CHI, XIAO-KUN YAO, HUI-JUAN WU, YONG-ZHI LUN. Inhibitory effects of the recombinant human serine protease inhibitor Hespintor on the proliferation, migration and invasion of hepatocellular carcinoma cells. Oncology Reports 2015; 33(2): 729 doi: 10.3892/or.2014.3670
|
| 10 |
Xitong Dang, Raul Coimbra, Liang Mao, Sonia Podvin, Xue Li, Hua Yu, Todd W. Costantini, Xiaorong Zeng, Dana Larocca, Brian P. Eliceiri, Andrew Baird. Open reading frame mining identifies a TLR4 binding domain in the primary sequence of ECRG4. Cellular and Molecular Life Sciences 2019; 76(24): 5027 doi: 10.1007/s00018-019-03159-5
|
| 11 |
Jiayu Chen, Chibo Liu, Lihui Yin, Wei Zhang. The tumor-promoting function of ECRG4 in papillary thyroid carcinoma and its related mechanism. Tumor Biology 2015; 36(2): 1081 doi: 10.1007/s13277-014-2731-1
|
| 12 |
Ana Maria Gonzalez, Sonia Podvin, Shuh-Yow Lin, Miles C Miller, Hannah Botfield, Wendy E Leadbeater, Andrew Roberton, Xitong Dang, Stuart E Knowling, Elena Cardenas-Galindo, John E Donahue, Edward G Stopa, Conrad E Johanson, Raul Coimbra, Brian P Eliceiri, Andrew Baird. Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury. Fluids and Barriers of the CNS 2011; 8(1) doi: 10.1186/2045-8118-8-6
|
| 13 |
Zhengxu Cai, Pin Liang, Jize Xuan, Jiajia Wan, Huishu Guo. ECRG4 as a novel tumor suppressor gene inhibits colorectal cancer cell growth in vitro and in vivo. Tumor Biology 2016; 37(7): 9111 doi: 10.1007/s13277-015-4775-2
|
| 14 |
Junichi Matsuzaki, Toshihiko Torigoe, Yoshihiko Hirohashi, Kenjiro Kamiguchi, Yasuaki Tamura, Tomohide Tsukahara, Terufumi Kubo, Akari Takahashi, Emiri Nakazawa, Eri Saka, Kazuyo Yasuda, Shuji Takahashi, Noriyuki Sato. ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells. Carcinogenesis 2012; 33(5): 996 doi: 10.1093/carcin/bgs118
|
| 15 |
Liang Mao, Xue Li, Shu Gong, Haiyang Yuan, Yu Jiang, Wenjun Huang, Xingwang Sun, Xitong Dang. Serum exosomes contain ECRG4 mRNA that suppresses tumor growth via inhibition of genes involved in inflammation, cell proliferation, and angiogenesis. Cancer Gene Therapy 2018; 25(9-10): 248 doi: 10.1038/s41417-018-0032-3
|
| 16 |
Lin‐Wei Li, Xi‐Ying Yu, Yang Yang, Chun‐Peng Zhang, Li‐Ping Guo, Shih‐Hsin Lu. Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro and in vivo. International Journal of Cancer 2009; 125(7): 1505 doi: 10.1002/ijc.24513
|
| 17 |
Yuka Nakatani, Hiroshi Kiyonari, Toru Kondo. Ecrg4 deficiency extends the replicative capacity of neural stem cells in a Foxg1-dependent manner. Development 2019; 146(4) doi: 10.1242/dev.168120
|
| 18 |
JIANPING JIA, SONG DAI, XINGHE SUN, YUEHONG SANG, ZHENMING XU, JIE ZHANG, XIAOFENG CUI, JINHUI SONG, XING GUO. A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms. Molecular Medicine Reports 2015; 12(4): 5058 doi: 10.3892/mmr.2015.4059
|
| 19 |
Junichi Matsuzaki, Toshihiko Torigoe, Yoshihiko Hirohashi, Yasuaki Tamura, Hiroko Asanuma, Emiri Nakazawa, Eri Saka, Kazuyo Yasuda, Shuji Takahashi, Noriyuki Sato. Expression of ECRG4 is associated with lower proliferative potential of esophageal cancer cells. Pathology International 2013; 63(8): 391 doi: 10.1111/pin.12079
|
| 20 |
Chaoyang Li, Pengju Zhang, Anli Jiang, Jian-Hua Mao, Guangwei Wei. A short synthetic peptide fragment of human C2ORF40 has therapeutic potential in breast cancer. Oncotarget 2017; 8(26): 41963 doi: 10.18632/oncotarget.16713
|
| 21 |
Akihiko Ozawa, Adam N. Lick, Iris Lindberg. Processing of Proaugurin Is Required to Suppress Proliferation of Tumor Cell Lines. Molecular Endocrinology 2011; 25(5): 776 doi: 10.1210/me.2010-0389
|
| 22 |
M.L. McCabe, Z. Dlamini. The molecular mechanisms of oesophageal cancer. International Immunopharmacology 2005; 5(7-8): 1113 doi: 10.1016/j.intimp.2004.11.017
|
| 23 |
Nannan Feng, Yu Wang, Min Zheng, Xiao Yu, Hongyan Lin, Rong-Na Ma, Oumin Shi, Xiangqian Zheng, Ming Gao, Herbert Yu, Lana Garmire, Biyun Qian. Genome-Wide Analysis of Dna Methylation and Their Associations With Long Noncoding Rna/Mrna Expression in Non-Small-Cell Lung Cancer. Epigenomics 2017; 9(2): 137 doi: 10.2217/epi-2016-0120
|
| 24 |
JA Tadross, M Patterson, K Suzuki, KE Beale, CK Boughton, KL Smith, S Moore, MA Ghatei, SR Bloom. Augurin stimulates the hypothalamo‐pituitary‐adrenal axis via the release of corticotrophin‐releasing factor in rats. British Journal of Pharmacology 2010; 159(8): 1663 doi: 10.1111/j.1476-5381.2010.00655.x
|
| 25 |
Xitong Dang, Sonia Podvin, Raul Coimbra, Brian Eliceiri, Andrew Baird. Cell-specific processing and release of the hormone-like precursor and candidate tumor suppressor gene product, Ecrg4. Cell and Tissue Research 2012; 348(3): 505 doi: 10.1007/s00441-012-1396-6
|
| 26 |
Lin-wei Li, Yuan-yuan Li, Xiao-yan Li, Chun-peng Zhang, Yun Zhou, Shih-Hsin Lu. A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma. BMC Cancer 2011; 11(1) doi: 10.1186/1471-2407-11-52
|
| 27 |
Liya Luo, Jianting Wu, Jun Xie, Lingling Xia, Xuemin Qian, Zhiming Cai, Zesong Li. Downregulated ECRG4 is associated with poor prognosis in renal cell cancer and is regulated by promoter DNA methylation. Tumor Biology 2016; 37(1): 1121 doi: 10.1007/s13277-015-3913-1
|
| 28 |
Xitong Dang, Xiaorong Zeng, Raul Coimbra, Brian P. Eliceiri, Andrew Baird. Counter regulation of ECRG4 gene expression by hypermethylation-dependent inhibition and the Sp1 transcription factor-dependent stimulation of the c2orf40 promoter. Gene 2017; 636: 103 doi: 10.1016/j.gene.2017.08.041
|
| 29 |
Margaux Richter, Enzo Lalli, Carmen Ruggiero. Complex and pleiotropic signaling pathways regulated by the secreted protein augurin. Cell Communication and Signaling 2023; 21(1) doi: 10.1186/s12964-023-01090-8
|
| 30 |
Linwei Li, Chunpeng Zhang, Xiaoyan Li, ShihHsin Lu, Yun Zhou. The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma. Journal of Experimental & Clinical Cancer Research 2010; 29(1) doi: 10.1186/1756-9966-29-133
|
| 31 |
Chaoying Wang, Jianghui He, Chunyue Chen, Wenjun Luo, Xitong Dang, Liang Mao. A potential role of human esophageal cancer-related gene-4 in cardiovascular homeostasis. Gene 2024; 894: 147977 doi: 10.1016/j.gene.2023.147977
|
| 32 |
Hirozumi Mizuiri, Kazuhiro Yoshida, Tetsuya Toge, Naohide Oue, Phyu Phyu Aung, Tsuyoshi Noguchi, Wataru Yasui. DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1 is associated with tumor stage. Cancer Science 2005; 96(9): 571 doi: 10.1111/j.1349-7006.2005.00082.x
|
| 33 |
Steven Kao, Ashkaun Shaterian, David M. Cauvi, Xitong Dang, Hyun Bae Chun, Antonio De Maio, Todd W. Costantini, Raul Coimbra, Brian P. Eliceiri, Andrew Baird. Pulmonary preconditioning, injury, and inflammation modulate expression of the candidate tumor suppressor geneECRG4in lung. Experimental Lung Research 2015; 41(3): 162 doi: 10.3109/01902148.2014.983282
|
| 34 |
Zuozhong Xie, Wei Li, Jingang Ai, Jun Xie, Xiaowei Zhang. C2orf40 inhibits metastasis and regulates chemo-resistance and radio-resistance of nasopharyngeal carcinoma cells by influencing cell cycle and activating the PI3K/AKT/mTOR signaling pathway. Journal of Translational Medicine 2022; 20(1) doi: 10.1186/s12967-022-03446-z
|
| 35 |
TING XU, DAJIANG XIAO, XIN ZHANG. ECRG4 inhibits growth and invasiveness of squamous cell carcinoma of the head and neck in vitro and in vivo. Oncology Letters 2013; 5(6): 1921 doi: 10.3892/ol.2013.1298
|
| 36 |
Haoran Huo, Song Yang, Haotian Wu, Yuchen Sun, Ranran Zhao, Ruihao Ye, Dongdong Yan, Xuefang Shi, Jiankai Yang. Brain endothelial cells‐derived extracellular vesicles overexpressing ECRG4 inhibit glioma proliferation through suppressing inflammation and angiogenesis. Journal of Tissue Engineering and Regenerative Medicine 2021; 15(12): 1162 doi: 10.1002/term.3244
|
| 37 |
Xiao-Ping Huang, Tie-Hua Rong, Qiu-Liang Wu, Jian-Hua Fu, Hong Yang, Jin-Ming Zhao, Yan Fang. MCM4 expression in esophageal cancer from southern China and its clinical significance. Journal of Cancer Research and Clinical Oncology 2005; 131(10): 677 doi: 10.1007/s00432-005-0011-6
|
| 38 |
J.-Y. Chen, X. Wu, C.-Q. Hong, J. Chen, X.-L. Wei, L. Zhou, H.-X. Zhang, Y.-T. Huang, L. Peng. Downregulated ECRG4 is correlated with lymph node metastasis and predicts poor outcome for nasopharyngeal carcinoma patients. Clinical and Translational Oncology 2017; 19(1): 84 doi: 10.1007/s12094-016-1507-z
|
| 39 |
Akihiko Ozawa, Iris Lindberg, Bryan Roth, Wesley K. Kroeze. Deorphanization of Novel Peptides and Their Receptors. The AAPS Journal 2010; 12(3): 378 doi: 10.1208/s12248-010-9198-9
|
| 40 |
Andrew Baird, Raul Coimbra, Xitong Dang, Nicole Lopez, Jisook Lee, Michael Krzyzaniak, Robert Winfield, Bruce Potenza, Brian P Eliceiri. Cell surface localization and release of the candidate tumor suppressor Ecrg4 from polymorphonuclear cells and monocytes activate macrophages. Journal of Leukocyte Biology 2012; 91(5): 773 doi: 10.1189/jlb.1011503
|
| 41 |
Arwa Kurabi, Kwang Pak, Xitong Dang, Raul Coimbra, Brian P. Eliceiri, Allen F. Ryan, Andrew Baird, Johanna M. Brandner. Ecrg4 Attenuates the Inflammatory Proliferative Response of Mucosal Epithelial Cells to Infection. PLoS ONE 2013; 8(4): e61394 doi: 10.1371/journal.pone.0061394
|
| 42 |
Michael Rose, Sarah Bringezu, Laura Godfrey, David Fiedler, Nadine T. Gaisa, Maximilian Koch, Christian Bach, Susanne Füssel, Alexander Herr, Doreen Hübner, Jörg Ellinger, David Pfister, Ruth Knüchel, Manfred P. Wirth, Manja Böhme, Edgar Dahl. ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer. International Journal of Molecular Sciences 2020; 21(3): 1117 doi: 10.3390/ijms21031117
|
| 43 |
Sonia Podvin, Ana-Maria Gonzalez, Miles C. Miller, Xitong Dang, Hannah Botfield, John E. Donahue, Arwa Kurabi, Matthew Boissaud-Cooke, Ryan Rossi, Wendy E. Leadbeater, Conrad E. Johanson, Raul Coimbra, Edward G. Stopa, Brian P. Eliceiri, Andrew Baird, Colin Combs. Esophageal Cancer Related Gene-4 Is a Choroid Plexus-Derived Injury Response Gene: Evidence for a Biphasic Response in Early and Late Brain Injury. PLoS ONE 2011; 6(9): e24609 doi: 10.1371/journal.pone.0024609
|
| 44 |
Xufeng Li, Fuyou Zhou, Chunyu Jiang, Yinuo Wang, Yanqiang Lu, Fei Yang, Nengchao Wang, Haijun Yang, Yanfang Zheng, Jiren Zhang, Robert Dante. Identification of a DNA Methylome Profile of Esophageal Squamous Cell Carcinoma and Potential Plasma Epigenetic Biomarkers for Early Diagnosis. PLoS ONE 2014; 9(7): e103162 doi: 10.1371/journal.pone.0103162
|
| 45 |
Lingmi Hou, Maoshan Chen, Minghao Wang, Xiang Cui, Yanchun Gao, Tianyong Xing, Jingdong Li, Shishan Deng, Jiani Hu, Hongwei Yang, Jun Jiang. Systematic analyses of key genes and pathways in the development of invasive breast cancer. Gene 2016; 593(1): 1 doi: 10.1016/j.gene.2016.08.007
|
| 46 |
Andrew M. Kaz, William M. Grady. Epigenetic biomarkers in esophageal cancer. Cancer Letters 2014; 342(2): 193 doi: 10.1016/j.canlet.2012.02.036
|
| 47 |
Cheng-Ping Jiang, Bi-Hua Wu, Bai-Qiang Wang, Mao-Yong Fu, Ming Yang, Yue Zhou, Fu Liu. Overexpression of ECRG4 enhances chemosensitivity to 5-fluorouracil in the human gastric cancer SGC-7901 cell line. Tumor Biology 2013; 34(4): 2269 doi: 10.1007/s13277-013-0768-1
|
| 48 |
Donkena Krishna Vanaja, Mathias Ehrich, Dirk Van den Boom, John C. Cheville, R. Jeffrey Karnes, Donald J. Tindall, Charles R. Cantor, Charles Y.F. Young. Hypermethylation of Genes for Diagnosis and Risk Stratification of Prostate Cancer. Cancer Investigation 2009; 27(5): 549 doi: 10.1080/07357900802620794
|
| 49 |
Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang. Potential functions of esophageal cancer-related gene-4 in the cardiovascular system. Frontiers of Medicine 2019; 13(6): 639 doi: 10.1007/s11684-019-0701-0
|
| 50 |
Toru Kondo. Glioblastoma-initiating cell heterogeneity generated by the cell-of-origin, genetic/epigenetic mutation and microenvironment. Seminars in Cancer Biology 2022; 82: 176 doi: 10.1016/j.semcancer.2020.12.003
|
| 51 |
Arwa Kurabi, Dong Gu Hur, Kwang Pak, Madeline Gibson, Nicholas J. G. Webster, Andrew Baird, Brian P. Eliceiri, Allen F. Ryan. The ECRG4 cleavage product augurin binds the endotoxin receptor and influences the innate immune response during otitis media. Frontiers in Genetics 2022; 13 doi: 10.3389/fgene.2022.932555
|
| 52 |
Silke Götze, Valeska Feldhaus, Thilo Traska, Marietta Wolter, Guido Reifenberger, Andrea Tannapfel, Cornelius Kuhnen, Dirk Martin, Oliver Müller, Sonja Sievers.
ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma. BMC Cancer 2009; 9(1) doi: 10.1186/1471-2407-9-447
|
| 53 |
Jing Lu, Mingxin Wen, Yurong Huang, Xiuquan He, Yunshan Wang, Qi Wu, Zengchun Li, Andres Castellanos-Martin, Mar Abad, Juan J. Cruz-Hernandez, Cesar A. Rodriguez, Jesus Perez-Losada, Jian-Hua Mao, Guangwei Wei. C2ORF40suppresses breast cancer cell proliferation and invasion through modulating expression of M phase cell cycle genes. Epigenetics 2013; 8(6): 571 doi: 10.4161/epi.24626
|
| 54 |
Da-Long Wu, Feng-Ying Sui, Xiao-Ming Jiang, Xiao-Hong Jiang. Methylation in esophageal carcinogenesis. World Journal of Gastroenterology 2006; 12(43): 6933-6940 doi: 10.3748/wjg.v12.i43.6933
|
| 55 |
Katie D. Pool, Gracie J. Hemmat, Robert A. Dorschner, Jordan Robin Yaron. ECRG4 mediates host response to cutaneous infection by regulating neutrophil recruitment and adhesion receptor expression. PLOS ONE 2024; 19(11): e0310810 doi: 10.1371/journal.pone.0310810
|
| 56 |
Sonia Podvin, Xitong Dang, Morgan Meads, Arwa Kurabi, Todd Costantini, Brian P. Eliceiri, Andrew Baird, Raul Coimbra. Esophageal cancer-related gene-4 (ECRG4) interactions with the innate immunity receptor complex. Inflammation Research 2015; 64(2): 107 doi: 10.1007/s00011-014-0789-2
|
| 57 |
Remco van Doorn, Roderick C. Slieker, Stéphanie E. Boonk, Willem H. Zoutman, Jelle J. Goeman, Martine Bagot, Laurence Michel, Cornelis P. Tensen, Rein Willemze, Bas T. Heijmans, Maarten H. Vermeer. Epigenomic Analysis of Sézary Syndrome Defines Patterns of Aberrant DNA Methylation and Identifies Diagnostic Markers. Journal of Investigative Dermatology 2016; 136(9): 1876 doi: 10.1016/j.jid.2016.03.042
|
| 58 |
Linwei Li, Xiaoyan Li, Wenyu Wang, Tianhui Gao, Yun Zhou, Shixin Lu. Soluble purified recombinant C2ORF40 protein inhibits tumor cell growth in vivo by decreasing telomerase activity in esophageal squamous cell carcinoma. Oncology Letters 2016; 12(4): 2820 doi: 10.3892/ol.2016.4935
|