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For: Kostrzewski T, Cornforth T, Snow SA, Ouro-Gnao L, Rowe C, Large EM, Hughes DJ. Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease. World J Gastroenterol 2017; 23(2): 204-215 [PMID: 28127194 DOI: 10.3748/wjg.v23.i2.204]
URL: https://www.wjgnet.com/1007-9327/full/v23/i2/204.htm
Number Citing Articles
1
Franck Da-silva, Xavier Boulenc, Hélène Vermet, Pauline Compigne, Sabine Gerbal-Chaloin, Martine Daujat-Chavanieu, Sylvie Klieber, Patrick Poulin. Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin BindingJournal of Pharmaceutical Sciences 2018; 107(7): 1957 doi: 10.1016/j.xphs.2018.03.001
2
Abdul M. Oseini, Banumathi K. Cole, Danny Issa, Ryan E. Feaver, Arun J. Sanyal. Translating scientific discovery: the need for preclinical models of nonalcoholic steatohepatitisHepatology International 2018; 12(1): 6 doi: 10.1007/s12072-017-9838-6
3
Aylin Acun, Letao Fan, Ruben Oganesyan, Korkut M. Uygun, Heidi Yeh, Martin L. Yarmush, Basak E. Uygun. Effect of Donor Age and Liver Steatosis on Potential of Decellularized Liver Matrices to be used as a Platform for iPSC‐Hepatocyte CultureAdvanced Healthcare Materials 2024; 13(13) doi: 10.1002/adhm.202302943
4
Banumathi K. Cole, Ryan E. Feaver, Brian R. Wamhoff, Ajit Dash. Non-alcoholic fatty liver disease (NAFLD) models in drug discoveryExpert Opinion on Drug Discovery 2018; 13(2): 193 doi: 10.1080/17460441.2018.1410135
5
Shi-Xiang Wang, Ji-Song Yan, Yun-Shen Chan. Advancements in MAFLD Modeling with Human Cell and Organoid ModelsInternational Journal of Molecular Sciences 2022; 23(19): 11850 doi: 10.3390/ijms231911850
6
David J Hughes, Tomasz Kostrzewski, Emma L Sceats. Opportunities and challenges in the wider adoption of liver and interconnected microphysiological systemsExperimental Biology and Medicine 2017; 242(16): 1593 doi: 10.1177/1535370217708976
7
Yasamin A. Jodat , Min G. Kang, Kiavash Kiaee, Gyeong J. Kim, Angel F.H. Martinez, Aliza Rosenkranz, Hojae Bae , Su R. Shin. Human-Derived Organ-on-a-Chip for Personalized Drug DevelopmentCurrent Pharmaceutical Design 2019; 24(45): 5471 doi: 10.2174/1381612825666190308150055
8
Francois Taute, Antoni Homs-Corbera, Pierre Gaudriault. The challenges and considerations for emerging or future entrepreneurial researchers in microphysiological systemsOpen Research Europe 2021; 1: 38 doi: 10.12688/openreseurope.13335.1
9
Nathalie K. Zgheib, Juan J.L. Lertora, Robert A. Branch. Atkinson's Principles of Clinical Pharmacology2022; : 91 doi: 10.1016/B978-0-12-819869-8.00005-7
10
Tim Brecklinghaus, Wiebke Albrecht, Julia Duda, Franziska Kappenberg, Lisa Gründler, Karolina Edlund, Rosemarie Marchan, Ahmed Ghallab, Cristina Cadenas, Adrian Rieck, Nachiket Vartak, Laia Tolosa, José V. Castell, Iain Gardner, Emina Halilbasic, Michael Trauner, Anett Ullrich, Anja Zeigerer, Özlem Demirci Turgunbayer, Georg Damm, Daniel Seehofer, Jörg Rahnenführer, Jan G. Hengstler. In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assayToxicology Letters 2022; 368: 33 doi: 10.1016/j.toxlet.2022.08.006
11
Nithin R, Ayushi Aggarwal, Anne Boyina Sravani, Pooja Mallya, Shaila Lewis. Organ-On-A-Chip: An Emerging Research PlatformOrganogenesis 2023; 19(1) doi: 10.1080/15476278.2023.2278236
12
Christoph Grün, Brigitte Altmann, Eric Gottwald. Advanced 3D Cell Culture Techniques in Micro-Bioreactors, Part I: A Systematic Analysis of the Literature Published between 2000 and 2020Processes 2020; 8(12): 1656 doi: 10.3390/pr8121656
13
Sundhar Mohandas, Kriya Kumaran, Kunka Mohanram Ramkumar. Human Organs-on-a-Chip Technology2024; : 261 doi: 10.1016/B978-0-443-13782-2.00001-2
14
Alexandre J. S. Ribeiro, Xinning Yang, Vikram Patel, Rajnikanth Madabushi, David G. Strauss. Liver Microphysiological Systems for Predicting and Evaluating Drug EffectsClinical Pharmacology & Therapeutics 2019; 106(1): 139 doi: 10.1002/cpt.1458
15
Andreas R. Baudy, Monicah A. Otieno, Philip Hewitt, Jinping Gan, Adrian Roth, Douglas Keller, Radhakrishna Sura, Terry R. Van Vleet, William R. Proctor. Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industryLab on a Chip 2020; 20(2): 215 doi: 10.1039/C9LC00768G
16
Bhumika Singh, Mohamed Essameldin Abdelgawad, Zulfiqur Ali, Jarrod Bailey, Elisa Budyn, Prospero Civita, Martin J.D. Clift, John T. Connelly, Samuel Constant, Marius Hittinger, Helena Kandarova, Victoria Rosalind Kearns, Tony Kiuru, Tomasz Kostrzewski, Sebastian Kress, Victoria Marsh Durban, Claus-Michael Lehr, Hayley McMillan, Julia Katharina Metz, Vivian Monteban, Dania Movia, Catia Neto, Carla Owen, Lauri Paasonen, Kerri Anne Palmer, Geoffrey John Pilkington, Karen Pilkington, Adriele Prina-Mello, Clive Roper, Jonathan Sheard, Sheree Smith, Janette Ellen Turner, Ipsita Roy, Melissa Anne Tutty, Eirini Velliou, John Malcolm Wilkinson. Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference ProceedingsAlternatives to Laboratory Animals 2021; 49(3): 93 doi: 10.1177/02611929211025006
17
Yaqing Wang, Hui Wang, Pengwei Deng, Tingting Tao, Haitao Liu, Shuo Wu, Wenwen Chen, Jianhua Qin. Modeling Human Nonalcoholic Fatty Liver Disease (NAFLD) with an Organoids-on-a-Chip SystemACS Biomaterials Science & Engineering 2020; 6(10): 5734 doi: 10.1021/acsbiomaterials.0c00682
18
Ehsanollah Moradi, Sasan Jalili-Firoozinezhad, Mehran Solati-Hashjin. Microfluidic organ-on-a-chip models of human liver tissueActa Biomaterialia 2020; 116: 67 doi: 10.1016/j.actbio.2020.08.041
19
Albert Gough, Alejandro Soto-Gutierrez, Lawrence Vernetti, Mo R. Ebrahimkhani, Andrew M. Stern, D. Lansing Taylor. Human biomimetic liver microphysiology systems in drug development and precision medicineNature Reviews Gastroenterology & Hepatology 2021; 18(4): 252 doi: 10.1038/s41575-020-00386-1
20
Clare L. Thompson, Su Fu, Hannah K. Heywood, Martin M. Knight, Stephen D. Thorpe. Mechanical Stimulation: A Crucial Element of Organ-on-Chip ModelsFrontiers in Bioengineering and Biotechnology 2020; 8 doi: 10.3389/fbioe.2020.602646
21
Kelsey Retting, Dwayne Carter, Candace Crogan-Grundy, Chirag Khatiwala, Leah Norona, Elizabeth Paffenroth, Umesh Hanumegowda, Alice Chen, Lisa Hazelwood, Lois Lehman-McKeeman, Sharon Presnell. Modeling Liver Biology and the Tissue Response to Injury in Bioprinted Human Liver TissuesApplied In Vitro Toxicology 2018; 4(3): 288 doi: 10.1089/aivt.2018.0015
22
Tomasz Kostrzewski, Paloma Maraver, Larissa Ouro‐Gnao, Ana Levi, Sophie Snow, Alina Miedzik, Krista Rombouts, David Hughes. A Microphysiological System for Studying Nonalcoholic SteatohepatitisHepatology Communications 2020; 4(1): 77 doi: 10.1002/hep4.1450
23
Yimu Zhao, Erika Yan Wang, Fook B.L. Lai, Krisco Cheung, Milica Radisic. Organs-on-a-chip: a union of tissue engineering and microfabricationTrends in Biotechnology 2023; 41(3): 410 doi: 10.1016/j.tibtech.2022.12.018
24
Veronica Zingales, Maria Rosaria Esposito, Noemi Torriero, Mercedes Taroncher, Elisa Cimetta, María-José Ruiz. The Growing Importance of Three-Dimensional Models and Microphysiological Systems in the Assessment of Mycotoxin ToxicityToxins 2023; 15(7): 422 doi: 10.3390/toxins15070422
25
Eric Wang, Melisa J. Andrade, Quinton Smith. Vascularized liver-on-a-chip model to investigate nicotine-induced dysfunctionBiomicrofluidics 2023; 17(6) doi: 10.1063/5.0172677
26
Joost Boeckmans, Alessandra Natale, Karolien Buyl, Vera Rogiers, Joery De Kock, Tamara Vanhaecke, Robim M. Rodrigues. Human-based systems: Mechanistic NASH modelling just around the corner?Pharmacological Research 2018; 134: 257 doi: 10.1016/j.phrs.2018.06.029
27
Seung Yeon Lee, Jong Hwan Sung. Gut–liver on a chip toward an in vitro model of hepatic steatosisBiotechnology and Bioengineering 2018; 115(11): 2817 doi: 10.1002/bit.26793
28
Helle Sedighi Frandsen, Joel Mario Vej-Nielsen, Lauren Elizabeth Smith, Lang Sun, Karoline Lindgaard Mikkelsen, Annemette Præstegaard Thulesen, Christina Erika Hagensen, Fuquan Yang, Adelina Rogowska-Wrzesinska. Mapping Proteome and Lipidome Changes in Early-Onset Non-Alcoholic Fatty Liver Disease Using Hepatic 3D SpheroidsCells 2022; 11(20): 3216 doi: 10.3390/cells11203216
29
Sophie Bauer, Charlotte Wennberg Huldt, Kajsa P. Kanebratt, Isabell Durieux, Daniela Gunne, Shalini Andersson, Lorna Ewart, William G. Haynes, Ilka Maschmeyer, Annika Winter, Carina Ämmälä, Uwe Marx, Tommy B. Andersson. Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes modelScientific Reports 2017; 7(1) doi: 10.1038/s41598-017-14815-w
30
Tomasz Kostrzewski, Sophie Snow, Anya Lindström Battle, Samantha Peel, Zahida Ahmad, Jayati Basak, Manasa Surakala, Aurelie Bornot, Julia Lindgren, Maria Ryaboshapkina, Maryam Clausen, Daniel Lindén, Christian Maass, Lucy May Young, Adam Corrigan, Lorna Ewart, David Hughes. Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological systemCommunications Biology 2021; 4(1) doi: 10.1038/s42003-021-02616-x
31
Ravi Adinarayan Somabattini, Sahla Sherin, Bhukya Siva, Neelanjan Chowdhury, Satheesh Kumar Nanjappan. Unravelling the complexities of non-alcoholic steatohepatitis: The role of metabolism, transporters, and herb-drug interactionsLife Sciences 2024; 351: 122806 doi: 10.1016/j.lfs.2024.122806
32
Carlemi Calitz, Josias H. Hamman, Stephen J. Fey, Krzysztof Wrzesinski, Chrisna Gouws. Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspectiveToxicology Mechanisms and Methods 2018; 28(5): 369 doi: 10.1080/15376516.2017.1422580
33
Ceri‐Anne E. Suurmond, Soufian Lasli, Floor W. van den Dolder, Aly Ung, Han‐Jun Kim, Praveen Bandaru, KangJu Lee, Hyun‐Jong Cho, Samad Ahadian, Nureddin Ashammakhi, Mehmet R. Dokmeci, Junmin Lee, Ali Khademhosseini. In Vitro Human Liver Model of Nonalcoholic Steatohepatitis by Coculturing Hepatocytes, Endothelial Cells, and Kupffer CellsAdvanced Healthcare Materials 2019; 8(24) doi: 10.1002/adhm.201901379
34
Alex J. Wang, Allysa Allen, Marianna Sofman, Pierre Sphabmixay, Ece Yildiz, Linda G. Griffith. Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic PhenotypesAdvanced NanoBiomed Research 2022; 2(1) doi: 10.1002/anbr.202100049
35
Camilo Rey-Bedon, Peony Banik, Aslihan Gokaltun, O. Hofheinz, Martin.L. Yarmush, M. Korkut Uygun, O. Berk Usta. CYP450 drug inducibility in NAFLD via an in vitro hepatic model: Understanding drug-drug interactions in the fatty liverBiomedicine & Pharmacotherapy 2022; 146: 112377 doi: 10.1016/j.biopha.2021.112377
36
Alexandra Gatzios, Matthias Rombaut, Karolien Buyl, Joery De Kock, Robim M. Rodrigues, Vera Rogiers, Tamara Vanhaecke, Joost Boeckmans. From NAFLD to MAFLD: Aligning Translational In Vitro Research to Clinical InsightsBiomedicines 2022; 10(1): 161 doi: 10.3390/biomedicines10010161
37
Sayaka Deguchi, Kazuo Takayama. State-of-the-art liver disease research using liver-on-a-chipInflammation and Regeneration 2022; 42(1) doi: 10.1186/s41232-022-00248-0
38
Hui Wang, Yue Zhu, Pengcheng Shi, Xiangyang Li, Qingyun Bu, Yachun Li, Xiaoyan You, Guoping Zhao. Ginsenoside Rb1 improves human nonalcoholic fatty liver disease with liver organoids-on-a-chipEngineered Regeneration 2024; 5(3): 283 doi: 10.1016/j.engreg.2024.06.002
39
Collin D. Edington, Wen Li Kelly Chen, Emily Geishecker, Timothy Kassis, Luis R. Soenksen, Brij M. Bhushan, Duncan Freake, Jared Kirschner, Christian Maass, Nikolaos Tsamandouras, Jorge Valdez, Christi D. Cook, Tom Parent, Stephen Snyder, Jiajie Yu, Emily Suter, Michael Shockley, Jason Velazquez, Jeremy J. Velazquez, Linda Stockdale, Julia P. Papps, Iris Lee, Nicholas Vann, Mario Gamboa, Matthew E. LaBarge, Zhe Zhong, Xin Wang, Laurie A. Boyer, Douglas A. Lauffenburger, Rebecca L. Carrier, Catherine Communal, Steven R. Tannenbaum, Cynthia L. Stokes, David J. Hughes, Gaurav Rohatgi, David L. Trumper, Murat Cirit, Linda G. Griffith. Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology StudiesScientific Reports 2018; 8(1) doi: 10.1038/s41598-018-22749-0
40
Vimal Veeriah, Seung-Hee Lee, Fred Levine. Long-term oral administration of an HNF4α agonist prevents weight gain and hepatic steatosis by promoting increased mitochondrial mass and functionCell Death & Disease 2022; 13(1) doi: 10.1038/s41419-022-04521-5
41
Shuyun Rao, Xiaochun Yang, Kazufumi Ohshiro, Sobia Zaidi, Zhanhuai Wang, Kirti Shetty, Xiyan Xiang, Md. Imtaiyaz Hassan, Taj Mohammad, Patricia S. Latham, Bao-Ngoc Nguyen, Linda Wong, Herbert Yu, Yousef Al-Abed, Bibhuti Mishra, Michele Vacca, Gareth Guenigault, Michael E. D. Allison, Antonio Vidal-Puig, Jihane N. Benhammou, Marcus Alvarez, Päivi Pajukanta, Joseph R. Pisegna, Lopa Mishra. β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer developmentScience Translational Medicine 2021; 13(624) doi: 10.1126/scitranslmed.abk2267
42
Qianqian Xu. Human Three-Dimensional Hepatic Models: Cell Type Variety and Corresponding ApplicationsFrontiers in Bioengineering and Biotechnology 2021; 9 doi: 10.3389/fbioe.2021.730008
43
Shabir Hassan, Shikha Sebastian, Sushila Maharjan, Ami Lesha, Anne‐Marie Carpenter, Xiuli Liu, Xin Xie, Carol Livermore, Yu Shrike Zhang, Ali Zarrinpar. Liver‐on‐a‐Chip Models of Fatty Liver DiseaseHepatology 2020; 71(2): 733 doi: 10.1002/hep.31106
44
Jiu Deng, Wenbo Wei, Zongzheng Chen, Bingcheng Lin, Weijie Zhao, Yong Luo, Xiuli Zhang. Engineered Liver-On-A-Chip Platform to Mimic Liver Functions and Its Biomedical Applications: A ReviewMicromachines 2019; 10(10): 676 doi: 10.3390/mi10100676
45
Shengnan Ya, Weiping Ding, Shibo Li, Kun Du, Yuanyuan Zhang, Chengpan Li, Jing Liu, Fenfen Li, Ping Li, Tianzhi Luo, Liqun He, Ao Xu, Dayong Gao, Bensheng Qiu. On-Chip Construction of Liver Lobules with Self-Assembled Perfusable Hepatic Sinusoid NetworksACS Applied Materials & Interfaces 2021; 13(28): 32640 doi: 10.1021/acsami.1c00794
46
Ajit Dash, William R. Proctor. Microfluidic Cell Culture Systems2019; : 159 doi: 10.1016/B978-0-12-813671-3.00006-2
47
Pierre Sphabmixay, Micha Sam Brickman Raredon, Alex J-S Wang, Howon Lee, Paula T Hammond, Nicholas X Fang, Linda G Griffith. High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modelingBiofabrication 2021; 13(4): 045024 doi: 10.1088/1758-5090/ac23aa
48
Kun Du, Shibo Li, Chengpan Li, Ping Li, Chunguang Miao, Tianzhi Luo, Bensheng Qiu, Weiping Ding. Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supplyActa Biomaterialia 2021; 134: 228 doi: 10.1016/j.actbio.2021.07.013
49
Volker M. Lauschke, Reza Z. Shafagh, Delilah F. G. Hendriks, Magnus Ingelman‐Sundberg. 3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and ApplicationsBiotechnology Journal 2019; 14(7) doi: 10.1002/biot.201800347
50
Seung Yeon Lee, Donghyun Kim, Seung Hwan Lee, Jong Hwan Sung. Microtechnology-based in vitro models: Mimicking liver function and pathophysiologyAPL Bioengineering 2021; 5(4) doi: 10.1063/5.0061896
51
Dennis McDuffie, David Barr, Madeline Helm, Thomas Baumert, Ashutosh Agarwal, Emmanuel Thomas. Physiomimetic In Vitro Human Models for Viral Infection in the LiverSeminars in Liver Disease 2023; 43(01): 031 doi: 10.1055/a-1981-5944
52
Charlotte J. Green, Siôn A. Parry, Pippa J. Gunn, Carlo D.L. Ceresa, Fredrik Rosqvist, Marie-Eve Piché, Leanne Hodson. Studying non-alcoholic fatty liver disease: the ins and outs of in vivo, ex vivo and in vitro human modelsHormone Molecular Biology and Clinical Investigation 2020; 41(1) doi: 10.1515/hmbci-2018-0038
53
Zahra Koohestani Sini, Mohammad Esmaeil Afzalpour, Mohsen Mohammadnia Ahmadi, Mohammad Ali Sardar, Sattar Gorgani Firuzjaee. The Effect of Aerobic Continuous Training on Myonectin, Insulin Resistance and Liver Enzymes in Rats with Nonalcoholic Fatty Liver DiseaseAnnals of Applied Sport Science 2020; 8(4): 0 doi: 10.29252/aassjournal.855
54
Kelly Tan, Philip Keegan, Miles Rogers, Mingjian Lu, James R. Gosset, Joe Charest, Shyam Sundhar Bale. A high-throughput microfluidic microphysiological system (PREDICT-96) to recapitulate hepatocyte function in dynamic, re-circulating flow conditionsLab on a Chip 2019; 19(9): 1556 doi: 10.1039/C8LC01262H
55
Yao Teng, Zixuan Zhao, Farah Tasnim, Xiaozhong Huang, Hanry Yu. A scalable and sensitive steatosis chip with long-term perfusion of in situ differentiated HepaRG organoidsBiomaterials 2021; 275: 120904 doi: 10.1016/j.biomaterials.2021.120904
56
Jiu Deng, Xiuli Zhang, Zongzheng Chen, Yong Luo, Yao Lu, Tingjiao Liu, Zhengzhi Wu, Yu Jin, Weijie Zhao, Bingcheng Lin. A cell lines derived microfluidic liver model for investigation of hepatotoxicity induced by drug-drug interactionBiomicrofluidics 2019; 13(2) doi: 10.1063/1.5070088
57
Rajagopal N. Aravalli, Clifford J. Steer. Utility of Common Marmoset (Callithrix jacchus) Embryonic Stem Cells in Liver Disease Modeling, Tissue Engineering and Drug MetabolismGenes 2020; 11(7): 729 doi: 10.3390/genes11070729
58
Mikael Kozyra, Inger Johansson, Åsa Nordling, Shahid Ullah, Volker M. Lauschke, Magnus Ingelman-Sundberg. Human hepatic 3D spheroids as a model for steatosis and insulin resistanceScientific Reports 2018; 8(1) doi: 10.1038/s41598-018-32722-6
59
Kirk P. Van Ness, Francine Cesar, Catherine K. Yeung, Jonathan Himmelfarb, Edward J. Kelly. Microphysiological systems in absorption, distribution, metabolism, and elimination sciencesClinical and Translational Science 2022; 15(1): 9 doi: 10.1111/cts.13132
60
Simon Ströbel, Radina Kostadinova, Katia Fiaschetti-Egli, Jana Rupp, Manuela Bieri, Agnieszka Pawlowska, Donna Busler, Thomas Hofstetter, Katarzyna Sanchez, Sue Grepper, Eva Thoma. A 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidatesScientific Reports 2021; 11(1) doi: 10.1038/s41598-021-01951-7
61
Charlotte J. Green, Thomas Marjot, Jeremy W. Tomlinson, Leanne Hodson. Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis?Diabetes, Obesity and Metabolism 2019; 21(4): 749 doi: 10.1111/dom.13592
62
Simran Kaur Rainu, Neetu Singh. 3D microscaffolds with triple-marker sensitive nanoprobes for studying fatty liver disease in vitroNanoscale 2024; 16(20): 10048 doi: 10.1039/D4NR00434E
63
Chase P. Monckton, Salman R. Khetani. Drug-Induced Liver ToxicityMethods in Pharmacology and Toxicology 2018; : 213 doi: 10.1007/978-1-4939-7677-5_11
64
Joong‐won Jeon, Seung Hwan Lee, Donghyun Kim, Jong Hwan Sung. In vitro hepatic steatosis model based on gut–liver‐on‐a‐chipBiotechnology Progress 2021; 37(3) doi: 10.1002/btpr.3121
65
Chase P. Monckton, Grace E. Brown, Salman R. Khetani. Latest impact of engineered human liver platforms on drug developmentAPL Bioengineering 2021; 5(3) doi: 10.1063/5.0051765
66
Michael J. Rupar, Hannah Hanson, Stephanie Rogers, Brianna Botlick, Steven Trimmer, James J. Hickman. Modelling the innate immune system in microphysiological systemsLab on a Chip 2024; 24(15): 3604 doi: 10.1039/D3LC00812F
67
Sonia Youhanna, Aurino M. Kemas, Lena Preiss, Yitian Zhou, Joanne X. Shen, Selgin D. Cakal, Francesco S. Paqualini, Sravan K. Goparaju, Reza Zandi Shafagh, Johan Ulrik Lind, Carl M. Sellgren, Volker M. Lauschke, Gunnar Schulte. Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development—Current State-of-the-Art and Future PerspectivesPharmacological Reviews 2022; 74(1): 141 doi: 10.1124/pharmrev.120.000238
68
Katharina S. Nitsche, Iris Müller, Sophie Malcomber, Paul L. Carmichael, Hans Bouwmeester. Implementing organ-on-chip in a next-generation risk assessment of chemicals: a reviewArchives of Toxicology 2022; 96(3): 711 doi: 10.1007/s00204-022-03234-0
69
Yasunori Tokuoka, Tadashi Ishida. Local Microbubble Removal in Polydimethylsiloxane Microchannel by Balancing Negative and Atmospheric PressuresMicromachines 2023; 15(1): 37 doi: 10.3390/mi15010037
70
Milad Rezvani, Ludovic Vallier, Adrien Guillot. Modeling Nonalcoholic Fatty Liver Disease in the Dish Using Human-Specific Platforms: Strategies and LimitationsCellular and Molecular Gastroenterology and Hepatology 2023; 15(5): 1135 doi: 10.1016/j.jcmgh.2023.01.014
71
Mohamed Albadry, Sebastian Höpfl, Nadia Ehteshamzad, Matthias König, Michael Böttcher, Jasna Neumann, Amelie Lupp, Olaf Dirsch, Nicole Radde, Bruno Christ, Madlen Christ, Lars Ole Schwen, Hendrik Laue, Robert Klopfleisch, Uta Dahmen. Periportal steatosis in mice affects distinct parameters of pericentral drug metabolismScientific Reports 2022; 12(1) doi: 10.1038/s41598-022-26483-6
72
M. Yu. Shkurnikov, E. N. Knyazev, K. A. Fomicheva, M. S. Kasatkin, V. V. Arkov, Yu. A. Makarova. Detection of Low-Abundant MicroRNAs with Hybridization MicrochipsBulletin of Experimental Biology and Medicine 2019; 166(6): 788 doi: 10.1007/s10517-019-04441-z
73
Norman C. Peterson, Prathap Kumar Mahalingaiah, Aaron Fullerton, Matteo Di Piazza. Application of microphysiological systems in biopharmaceutical research and developmentLab on a Chip 2020; 20(4): 697 doi: 10.1039/C9LC00962K
74
Jana Hundertmark, Frank Tacke. How effective are nonalcoholic fatty liver disease models for drug discovery?Expert Opinion on Drug Discovery 2020; 15(11): 1237 doi: 10.1080/17460441.2020.1776258
75
Tarun Agarwal, Aruja Rustagi, Joyjyoti Das, Tapas Kumar Maiti. PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applicationsColloids and Surfaces B: Biointerfaces 2018; 172: 346 doi: 10.1016/j.colsurfb.2018.08.062
76
Victoria L. Slaughter, John W. Rumsey, Rachel Boone, Duaa Malik, Yunqing Cai, Narasimhan Narasimhan Sriram, Christopher J. Long, Christopher W. McAleer, Stephen Lambert, Michael L. Shuler, J. J. Hickman. Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluationScientific Reports 2021; 11(1) doi: 10.1038/s41598-021-92264-2
77
Gregory H. Underhill, Salman R. Khetani. Advances in Engineered Human Liver Platforms for Drug Metabolism StudiesDrug Metabolism and Disposition 2018; 46(11): 1626 doi: 10.1124/dmd.118.083295
78
Francesco De Chiara, Juan M. Fernández-Costa, Javier Ramón-Azcón, Justyna Grochala, Anna Paleczek, Dominik Grochala, Artur Rydosz. Human Organs-On-a-chip2024; : 187 doi: 10.1016/B978-0-443-15384-6.00007-0
79
Elisa Cauli, Michela Anna Polidoro, Simona Marzorati, Claudio Bernardi, Marco Rasponi, Ana Lleo. Cancer-on-chip: a 3D model for the study of the tumor microenvironmentJournal of Biological Engineering 2023; 17(1) doi: 10.1186/s13036-023-00372-6
80
Mengying Xia, Mahboubeh Varmazyad, Iris Pla-Palacín, Dillon C. Gavlock, Richard DeBiasio, Gregory LaRocca, Celeste Reese, Rodrigo M. Florentino, Lanuza A. P. Faccioli, Jacquelyn A. Brown, Lawrence A. Vernetti, Mark Schurdak, Andrew M. Stern, Albert Gough, Jaideep Behari, Alejandro Soto-Gutierrez, D. Lansing Taylor, Mark T. Miedel. Comparison of wild-type and high-risk PNPLA3 variants in a human biomimetic liver microphysiology system for metabolic dysfunction-associated steatotic liver disease precision therapyFrontiers in Cell and Developmental Biology 2024; 12 doi: 10.3389/fcell.2024.1423936
81
Min Liu, Yuting Xiang, Yuqi Yang, Xingyu Long, Zuoxiu Xiao, Yayun Nan, Yitian Jiang, Yige Qiu, Qiong Huang, Kelong Ai. State-of-the-art advancements in Liver-on-a-chip (LOC): Integrated biosensors for LOCBiosensors and Bioelectronics 2022; 218: 114758 doi: 10.1016/j.bios.2022.114758
82
A. M. Ortega-Prieto, J. K. Skelton, S. N. Wai, E. Large, M. Lussignol, G. Vizcay-Barrena, D. Hughes, R. A. Fleck, M. Thursz, M. T. Catanese, M. Dorner. 3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infectionNature Communications 2018; 9(1) doi: 10.1038/s41467-018-02969-8
83
Somnath Maji, Minkyoung Lee, Jooyoung Lee, Jaehee Lee, Hyungseok Lee. Development of lumen-based perfusable 3D liver in vitro model using single-step bioprinting with composite bioinksMaterials Today Bio 2023; 21: 100723 doi: 10.1016/j.mtbio.2023.100723
84
Peerut Chienwichai, Onrapak Reamtong, Usa Boonyuen, Trairak Pisitkun, Poorichaya Somparn, Prapin Tharnpoophasiam, Suwalee Worakhunpiset, Supachai Topanurak. Hepatic protein Carbonylation profiles induced by lipid accumulation and oxidative stress for investigating cellular response to non-alcoholic fatty liver disease in vitroProteome Science 2019; 17(1) doi: 10.1186/s12953-019-0149-9
85
Linjie Qiu, Bin Kong, Tiantian Kong, Huan Wang. Recent advances in liver‐on‐chips: Design, fabrication, and applicationsSmart Medicine 2023; 2(1) doi: 10.1002/SMMD.20220010
86
Madeline Cooper, Joseph L. Charest, Jonathan Coppeta. Microfluidic Cell Culture Systems2019; : 1 doi: 10.1016/B978-0-12-813671-3.00001-3
87
Sen Liu, Chuanliang Cheng, Liuyang Zhu, Tianyu Zhao, Ze Wang, Xiulin Yi, Fengying Yan, Xiaoliang Wang, Chunli Li, Tao Cui, Baofeng Yang. Liver organoids: updates on generation strategies and biomedical applicationsStem Cell Research & Therapy 2024; 15(1) doi: 10.1186/s13287-024-03865-3
88
Alexander Marker, Jens Riedel, Angela Dudda, Gert Ulrich Kuerzel. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays2024; : 1 doi: 10.1007/978-3-030-73317-9_109-1
89
Elise A. Aeby, Patrick M. Misun, Andreas Hierlemann, Olivier Frey. Microfluidic Hydrogel Hanging‐Drop Network for Long‐Term Culturing of 3D Microtissues and Simultaneous High‐Resolution ImagingAdvanced Biosystems 2018; 2(7) doi: 10.1002/adbi.201800054
90
María Virumbrales-Muñoz, José M. Ayuso, Max M. Gong, Mouhita Humayun, Megan K. Livingston, Karina M. Lugo-Cintrón, Patrick McMinn, Yasmín R. Álvarez-García, David J. Beebe. Microfluidic lumen-based systems for advancing tubular organ modelingChemical Society Reviews 2020; 49(17): 6402 doi: 10.1039/D0CS00705F
91
Murat Cirit, Cynthia L. Stokes. Maximizing the impact of microphysiological systems with in vitro–in vivo translationLab on a Chip 2018; 18(13): 1831 doi: 10.1039/C8LC00039E
92
Impreet Kaur, Ashwini Vasudevan, Preety Rawal, Dinesh M. Tripathi, Seeram Ramakrishna, Savneet Kaur, Shiv K. Sarin. Primary Hepatocyte Isolation and Cultures: Technical Aspects, Challenges and AdvancementsBioengineering 2023; 10(2): 131 doi: 10.3390/bioengineering10020131
93
David A. Kukla, Salman R. Khetani. Bioengineered Liver Models for Investigating Disease Pathogenesis and Regenerative MedicineSeminars in Liver Disease 2021; 41(03): 368 doi: 10.1055/s-0041-1731016
94
Hanyuan Wang, Mathieu Danoy, Ya Gong, Tia Utami, Hiroshi Arakawa, Yukio Kato, Masaki Nishikawa, Yasuyuki Sakai, Eric Leclerc. Palmitic Acid Induced a Dedifferentiation Profile at the Transcriptome Level: A Collagen Synthesis but no Triglyceride Accumulation in Hepatocyte‐Like Cells Derived From Human‐Induced Pluripotent Stem Cells Cultivated Inside Organ on a ChipJournal of Applied Toxicology 2024;  doi: 10.1002/jat.4714
95
Ozlem Yesil‐Celiktas, Shabir Hassan, Amir K. Miri, Sushila Maharjan, Rawan Al‐kharboosh, Alfredo Quiñones‐Hinojosa, Yu Shrike Zhang. Mimicking Human Pathophysiology in Organ‐on‐Chip DevicesAdvanced Biosystems 2018; 2(10) doi: 10.1002/adbi.201800109
96
Jan Majer, Aneesh Alex, Jindou Shi, Eric J. Chaney, Prabuddha Mukherjee, Darold R. Spillman, Marina Marjanovic, Carla F. Newman, Reid M. Groseclose, Peter D. Watson, Stephen A. Boppart, Steve R. Hood. Multimodal imaging of a liver-on-a-chip model using labelled and label-free optical microscopy techniquesLab on a Chip 2024; 24(19): 4594 doi: 10.1039/D4LC00504J
97
Michela Anna Polidoro, Erika Ferrari, Simona Marzorati, Ana Lleo, Marco Rasponi. Experimental liver models: From cell culture techniques to microfluidic organs‐on‐chipLiver International 2021; 41(8): 1744 doi: 10.1111/liv.14942
98
Pierre-Antoine Soret, Julie Magusto, Chantal Housset, Jérémie Gautheron. In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical AppraisalJournal of Clinical Medicine 2020; 10(1): 36 doi: 10.3390/jcm10010036
99
Gregory H. Underhill, Salman R. Khetani. Emerging trends in modeling human liver disease in vitro APL Bioengineering 2019; 3(4) doi: 10.1063/1.5119090
100
Fabrice A. Müller, Shana J. Sturla. Human in vitro models of nonalcoholic fatty liver diseaseCurrent Opinion in Toxicology 2019; 16: 9 doi: 10.1016/j.cotox.2019.03.001
101
Pippa J. Gunn, Camilla Pramfalk, Val Millar, Thomas Cornfield, Matthew Hutchinson, Elspeth M. Johnson, Shilpa R. Nagarajan, Perla Troncoso‐Rey, Richard F. Mithen, Katherine E. Pinnick, Maria H. Traka, Charlotte J. Green, Leanne Hodson. Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosisPhysiological Reports 2020; 8(13) doi: 10.14814/phy2.14482
102
Alfredo Smiriglia, Nicla Lorito, Marina Serra, Andrea Perra, Andrea Morandi, Marta Anna Kowalik. Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinomaiScience 2023; 26(12): 108363 doi: 10.1016/j.isci.2023.108363
103
Alexander Marker, Jens Riedel, Angela Dudda, Gert Ulrich Kuerzel. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays2024; : 1623 doi: 10.1007/978-3-031-35529-5_109
104
Soufian Lasli, Han‐Jun Kim, KangJu Lee, Ceri‐Anne E. Suurmond, Marcus Goudie, Praveen Bandaru, Wujin Sun, Shiming Zhang, Niyuan Zhang, Samad Ahadian, Mehmet R. Dokmeci, Junmin Lee, Ali Khademhosseini. A Human Liver‐on‐a‐Chip Platform for Modeling Nonalcoholic Fatty Liver DiseaseAdvanced Biosystems 2019; 3(8) doi: 10.1002/adbi.201900104
105
Aarif Ali, Ishteyaq Majeed Shah, Mohammad Saleem Bhat, Zainab Manzoor, Aadil Ayaz, Muneeb U. Rehman, Sheikh Bilal Ahmad. Biological Insights of Multi-Omics Technologies in Human Diseases2024; : 339 doi: 10.1016/B978-0-443-23971-7.00014-6
106
Xinmei Xu, Suet Cheung, Xiaomeng Jia, Gang Fan, Yongjian Ai, Yi Zhang, Qionglin Liang. Trends in organ-on-a-chip for pharmacological analysisTrAC Trends in Analytical Chemistry 2024; 180: 117905 doi: 10.1016/j.trac.2024.117905
107
Ujjal Sarkar, Kodihalli C. Ravindra, Emma Large, Carissa L. Young, Dinelia Rivera-Burgos, Jiajie Yu, Murat Cirit, David J. Hughes, John S. Wishnok, Douglas A. Lauffenburger, Linda G. Griffith, Steven R. Tannenbaum. Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture SystemDrug Metabolism and Disposition 2017; 45(7): 855 doi: 10.1124/dmd.116.074005
108
Michele Vacca, Jack Leslie, Samuel Virtue, Brian Y. H. Lam, Olivier Govaere, Dina Tiniakos, Sophie Snow, Susan Davies, Kasparas Petkevicius, Zhen Tong, Vivian Peirce, Mette Juul Nielsen, Zsuzsanna Ament, Wei Li, Tomasz Kostrzewski, Diana Julie Leeming, Vlad Ratziu, Michael E. D. Allison, Quentin M. Anstee, Julian L. Griffin, Fiona Oakley, Antonio Vidal-Puig. Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitisNature Metabolism 2020; 2(6): 514 doi: 10.1038/s42255-020-0214-9
109
Rallia-Iliana Velliou, Eirini Giannousi, Christiana Ralliou, Eva Kassi, Antonios Chatzigeorgiou. Ex Vivo Tools and Models in MASLD ResearchCells 2024; 13(22): 1827 doi: 10.3390/cells13221827
110
Jiu Deng, Zongzheng Chen, Xiuli Zhang, Yong Luo, Zhengzhi Wu, Yao Lu, Tingjiao Liu, Weijie Zhao, Bingcheng Lin. A liver-chip-based alcoholic liver disease model featuring multi-non-parenchymal cellsBiomedical Microdevices 2019; 21(3) doi: 10.1007/s10544-019-0414-9
111
Khushi Karnawat, Rithika Parthasarathy, Mesevilhou Sakhrie, Harikeshav Karthik, Konatala Vibhuvan Krishna, Gowri Manohari Balachander. Building in vitro models for mechanistic understanding of liver regeneration in chronic liver diseasesJournal of Materials Chemistry B 2024; 12(32): 7669 doi: 10.1039/D4TB00738G
112
Cliff Rowe, Mohsen Shaeri, Emma Large, Terri Cornforth, Angela Robinson, Tomasz Kostrzewski, Rowena Sison-Young, Christopher Goldring, Kevin Park, David Hughes. Perfused human hepatocyte microtissues identify reactive metabolite-forming and mitochondria-perturbing hepatotoxinsToxicology in Vitro 2018; 46: 29 doi: 10.1016/j.tiv.2017.09.012